Is it normal for ceoliacs to have raised MCV and Alkaline Phosphatase in blood test results?

[Abbie_94]

[Lynxcat]

Hi Abbie, I'm not sure if anyone else may know the answer to this. So far the only thing I can offer are the following two links related to blood tests:

Interpreting Blood Tests and Investigations:

rcn.org.uk/__data/assets/pd...

Lab Testing Online

Lab Test Results Review Guide:

privatemdlabs.com/test_inte...

[Abbie_94]

Thanks I have looked them up and I already knew I had a folate dificancy but the doctors didnt seem to be fussed and that was back in january I think and its only been my psychaitrist who was concerned about my latest blood results I am due now to see my doctor next week but was only just wondering if this result is commonly seen in coeliacs

[jackieO]

Alk Phos is a marker of bone turnover. It is usually higher during periods of growth so normal values are higher in childhood than adulthood. However if you have had a low bone density from malabsorption reducing calcium and Vit D levels and these are now more normal you may well just be making new bone.

[Abbie_94]

Thanks well I do have perthes disease of my hip which ive had since i was 8 and that has made my hip joint deforemed and all that do you think that could be the cause?

[terri]

Did you also have your b12 levels checked - raised MCV can also be related to low b12 and I also think thyroid.

[Abbie_94]

Yeah a recent test showed my folate levels were low but my b12 were apparently fine

[NorthernSoul]

Folate or B12 deficiency can cause a raised MCV and ALP can be raised for a number of reasons (including bile duct disease and certain bone diseases including vitamin D deficiency- osteoporosis does not cause elevated ALP and I shouldn't have thought Perthes would either, unless you've had a recent operation on the bone or fracture). This all depends on how elevated your tests are, of course. A minor change may not be significant at all.

In all, I wouldn't worry. Your GP should be able to explain it all to you and order any further tests if necessary.