Historic results

[Whatnow1973]

I was diagnosed with Hashimotos in 2014 and because of having one auto immune condition I was consequently tested for others- including Coeliac. I tested negative but as you can see only just & due to a lifetime of IBS caused by wheat I was a low consumer of wheat based foods anyway. I gave up gluten in 2015 for good because it’s better for managing hashi’s & I’ve never looked back- no more IBS!

Now my Daughter has just been told she has Coeliac and I’m wondering if in fact I do too? So I dug out my old results and I’d be interested to hear you thoughts? I suppose nothing changes because I’m GF anyway?

Many thanks

Z

[angelias]

Hi,

I would say that it’s possible that you have Coeliac, considering that your daughter has been diagnosed and you have previously shown an “intolerance “ to wheat. However, like you said, blood test results cannot be reliable in this regard unless you eat gluten on a daily basis for at least a couple of weeks (or probably more?) before being tested again. I remember that even after going gluten free following my diagnosis about 8 years ago, my blood results still showed a very high level of antigliadin, and that was after being on a strict GF diet for several months.

[Whatnow1973 in reply to angelias]

Hi

Thanks for your reply.

Is antigliadin the same as IgA?

[angelias]

I think antigliadin would be “labelled” as

(AGA-)IgG

[Researchfan]

Hi. Interesting to look at historical results. As you say nothing changes though as gluten free.

There doesn’t seem to be a specific Coeliac Disease screen test on the panel you share? Example, ttg IgA, or ttg igG.

The endomysial is specific but tends to relate to severity of disease course and can be neg in early stages unlike the ttg test. But if pos almost definitely coeliac disease. The ANA is non specific but neg, if it had been pos that would also suggest possible Coeliac, or need for screening.

The serum immunoglobulins show not igA deficient etc.

The Crp and esr show inflammation. The hashis?

Have you had the genetic test as that can all but rule out coeliac disease (without eating wheat).

[Whatnow1973]

Thank you for your reply. I thought the IgA was the test for coeliac?

I haven’t had a genetic test, is this something I would do privately?

Thanks 😊

[Researchfan in reply to Whatnow1973]

Hi,

Yes, The igA anti-ttg antibody test is the specific Coeliac Screen test (according to present guidelines). It’s normal to also test total igA to make sure not deficient. The lab test results above read serum immunoglobulins and show totals?? You would need the ttg test (igA ttg or igG) but that requires eating gluten for at least six weeks normally.

Your labs may have been a more general autoimmune panel?

You can do the genetic test privately. Are you in the UK? It’s not the norm or NICE guidelines but quite possible under the care of an NHS gastroenterologist to get the genetic test to rule out Coeliac Disease. I was lucky enough to get the genetic test recommended, under the care of gastro. The gluten challenge made me ill, ttg IgA normal but high total. Genetic test doesn’t dx Coeliac Disease but can rule it out.

Hope that’s helpful info.

Just to add, if your daughter’s Coeliac. Odds are you are. Especially because you have hashi’s. Coeliac and Hashi’s tend to go together.

[Whatnow1973]

ps yes inflammation due to untreated hashi’s- it’s actually fairly normal levels these days.

[penelope2]

Well I am not familiar with your blood test results but I can tell you that general hospital labs do not do the tests TG6 which is the marker for gluten sensitivity. I think the CD test is not always picked up and Hospital labs are not always thorough or sensitive enough, they can vary.I have had blood tests done at one hospital that are negative and at another hospital that are positive! How do you explain that!

A hospital lab didn't pick up 2 intestinal microbes that a private lab did. These were making my daughter severely ill.

What I would say to you is if you are feeling better gluten free then go with what your body is telling you.

I was asked to eat gluten for 6 weeks to see if I tested positive for gluten antibodies, I refused and the doctor understood my reasons.

It can take a long time for gluten or giliandin antibodies to disappear from the body completely, 1 even 2 years.even if 100% gf.

Have faith in what you feel.

Take care.