Hello...just trying to find some answers to the many questions involving my late husbands passing almost 3 years ago. He had asthma most of his life. I believe it got worse over the years till he ended up in the hospital. He also had low iron to the extent of iron infusions. The first hospital stay they did xrays, ct scan, and lung function test. They said he had copd sent him home with oxygen. The next 3 months his condition got worse...breathing, cough, etc. Went back to hospital and they immediately vented him and said he had severe respiratory distress and then got pneumonia, DVT, & a large dose of blood thinner. After several days(9) and he didn't improve they finally tested him for aspergullis. It came back as Aspergillus fumigatus...I'm guessing it was ABPA? He finally passed away after 21 days he was only 49 years old. My questions are:
Could he have had this Aspergullis for many years undetected?
Could it had been the infection causing all the symptoms of copd?
Is there early signs and symptoms of ABPA that I could have seen?
All the tests they did while in the hospital both times..why didn't this show earlier?
Is there something on an xray or ct scan that stands out?
Is it possible he could have asthma, COPD, and ABPA all at the same time?
Please forgive me if these questions have been answered before, I have tried to search for these answers but it seems so complicated. Thanks for any help!
Hello - sorry for the delay in my reply
COPD is fairly commonly associated with Aspergillus infections of the airways as it can infect the scarring and areas that have poorer immune protection. It is most likely that COPD came first as it is that damage that encourages the fungal growth.
ABPA would probably have closely resembled COPD & asthma in terms of symptoms and may well be undetectable with so much other damage in the lungs - there was nothing you could have done about this as currently the diagnostic tests we have are not sufficient to reliably detect aspergillus infection.
ABPA may complicate asthma and there may be a type of asthma that is worsened by fungal infection - so all three could probably exist at the same time.
Thank you so much for your reply! Since I've written this I have come to find out that he didn't have COPD at all, that is was his long term Asthma and I guess the aspergillus that was causing his illness.
I have read that there are tests.....such as skin tests or a scope that can detect the infection is this correct? Assuming that aspergillus is suspected?