Progesterone Therapy May Improve COVID-19 Outcomes for Men - Cedars Sinai Study, Los Angeles, Mar18, 2021

[cujoe]

As a follow-up to my last post on the different COVID responses between the sexes, here is a new study from Cedar-Sinai about the effects of progesterone. Those damn sex hormones are at work again. Maybe this time in a good way. From the study:

COVID-19 disproportionately affects men compared with women, raising the possibility that a hormone like progesterone may improve clinical outcomes for certain hospitalized men with the disease. New research from Cedars-Sinai published online in the journal Chest supports this hypothesis.

. . .

Ghandehari hypothesized that the gender differences in disease outcomes might be due, in part, to a protective effect from female hormones. In particular, preclinical studies elsewhere had pointed to progesterone as having certain anti-inflammatory properties. This finding suggested progesterone might be useful in dampening a sometimes-fatal immune response, known as a "cytokine storm," that can worsen lung damage and attack other organs in COVID-19 patients.

Cedar Sinai Press Release is here:

cedars-sinai.org/newsroom/s...

And Journal Pre-Proof full report is here:

journal.chestnet.org/articl...

PCa patients do a real hormone dance once we start treatment. Others might be able to chime in as to the implications of this for those on ADT.

Peace - K9

[NPfisherman]

The problem with PCa and Progesterone is that Progesterone is a mixed bag of tricks when it comes to PCa. While progesterone may act as a 5 ARI, it may also cause progression of disease... info below:

ncbi.nlm.nih.gov/pmc/articl...

Balance those hormones, ye swabbies !!!

Fish