Blood test can guide treatment for most aggressive prostate cancer - Peter MacCallum Cancer Center, Victoria, AU

[cujoe]

An RNA-based liquid biopsy was able to detect abnormalities in the androgen receptor gene among men with metastatic castration-resistant prostate cancer, which could help guide treatment decisions. (Peter MacCallum Cancer Centre, European Urology)

From the press release:

From as little as 10ml of blood, the test can simultaneously profile the circulating DNA and RNA which is shed by cancer cells, offering important insights into the make-up of the cancer and treatments most likely (to) work.

. . .

They used this to test the blood of Australian men with mCRPC prior to treatment, accurately detecting some form of AR alteration in over half of patients.

. . .

The new liquid biopsy test from Predicine is also more informative than previous tests as it analyses two types of genetic material – DNA and RNA – to give a more in-depth and accurate insight into AR abnormalities within the cancer.?

Peter Mac Press Release:

Blood test can guide treatment for most aggressive prostate cancer

petermac.org/news/blood-tes...

European Urology Article (open access via sci-hub):

Combined Cell-free DNA and RNA Profiling of the Androgen Receptor: Clinical Utility of a Novel Multianalyte Liquid Biopsy Assay for Metastatic Prostate Cancer

sci-hub.tw/10.1016/j.eururo...

Predicine website link:

predicine.com/

More knowledge = more effective treatments. Be Well - K9

[marnieg46]

Thank you for posting cujoe. Work done at Peter MacCallum is amazing. Along with St Vincent's in Sydney, they are the leaders in PC trials and treatment in Australia.

[cujoe in reply to marnieg46]

Yes, they have a lot of fine research published in European Urology. Feel proud that your local MD researchers are on top of their PCa game.