I'm not sure whether I have been a member of this forum before, but think I haven't so will say hello as I have just joined now.
I wonder whether any of you have been on Duloxetine for some time and if so do the effects wear off? I was on it but mistakenly took 20mg once a day when it should have been twice, so when my GP told me about that I began twice a day but had night terrors (paralysis) so decided to come off altogether. It's now nearly 4 weeks and not only am I much lower in mood and weepy at times - though I know what those feelings are about and they relate mostly to my current life circumstances, the meds just dampened the emotions - but also my fibro pain is really bad at times, sometimes quite constantly in pain though other times it does ease.
I was just wondering about other people's experience of the med, also whether anyone takes anything for the muscle cramps - myofascial pain - as that's the worst thing I find.
Going on it was horrid with stomach cramps and sick feeling so I imagine coming off would not be pleasant. I have been on it for two years so it is difficult to gauge how much effect it is having. I don't fancy stopping and starting again to find out!
I guess I put my trust in the hands of the health professionals that it relieves fibro muscle pain and the mood stabiliser for someone with a chronic illness is a bonus.
I don't feel any side effects but guess this is one for you and your GP to discuss, perhaps start on a really low dose? I am on one 60mg gastro resistant capsule in the morning but gradually upped it. I guess because I didn't even think about going back for more it must be of some benefit.
Best of luck and hope your situation improves soon.