High level of Antibodies in sperm 96%

[Blueberryshrub]

Hi All, please does anybody have any recommendation on what to do about the high level of antibodies in sperm - 96% of sperms have antibodies attached to them. The other parameters are all ok and there is no issue with dna fragmentation (we have done all sorts of expensive tests). It is a recurring issue, all four tests done over the last 2 years are showing the same results. I understand ICSI can handle antibodies but with such a huge percentage, I am worried it is impacting the overall quality. We had one unsuccessful ICSI cycle where embryos started to deteriorate after day 4. Any advice is appreciated. Thank you!

[JA-fnuk Partner Nurse Fertility Network UK]

Have you discussed your concerns with your clinic ? Might help put your mind at ease The antibodies cause the sperm to stick together[clump] and so in high concentration ICSI is the treatment of choice The antibodies are " washed away " during preparation and then they select a sperm and inject it into the egg

Take care

Janet-Partner

[Blueberryshrub in reply to JA-fnuk]

Thank you, Janet. Yes, I am waiting for the clinic to call me but it is taking them weeks. So I thought I would check in here in case someone else had similar problems. One of the independent fertility specialists suggested for my partner to take Corticosteroids for a short time before my next IVF ICSI cycle but this doctor wasnt very convinced, it would make any difference.