Embryo containing a vacuole

[Sunshine1312]

We had 2 embryos with potential from our first round of IVF. One was graded 4AB and the other 4BB. They chose to transfer the 4BB embryo as the 4AB contained a vacuole. Unfortunately this transfer resulted in a negative test. We are hoping to go ahead with a FET in March, but I already have in my head that it isn’t going to work due to the embryo containing a vacuole and not being good enough the first time round despite being of a higher grade. I was wondering if anybody has experienced anything similar? Has anybody had a transfer with an embryo containing a vacuole and was it successful? Thanks for your help, I’m loving reading everyone else’s questions and thought I’d ask what’s been playing on my mind too.

[DianeArnold Partner Nurse Fertility Network UK]

Hi Sunshine. A vacuole is as the embryo moves on to blastocyst stage some fluid gets trapped. Once transferred it can sometimes continue normally. I have heard of that happening, so speak to your embryologist for guidance. Good luck. Diane

[Sunshine1312 in reply to DianeArnold]

Thank you DianeArnold . I’m trying to think positively but can’t help feel like we’re set up to fail with this one. On the other hand, why would they have chosen to store it if it was no good at all. Thanks again for your response ☺️