7th DE transfer BFN again - devastated 😥

[Staceywacey]

7th DE transfer BFN again - devastated 😢

I really don’t know what’s wrong with me,why are they not implanting.

I’ve had the ERA,intrapilids…. Linings always perfect,progesterone always good….

I’m numb.

[Skittles11]

Hi

I'm so sorry to learn this, it must be very upsetting for you

If I were in this position I think I'd want to be PGT-A testing any future embryos prior to transfer. A very personal choice and not for everyone but based on what you've said and the tests you've had this would be my next step.

Hugs xx

[Hoping20]

I’m so sorry you are going through this. This journey is so hard and painful. Try to be extra kind to yourself...you have been though so much. Take gentle steps to move forward but in the meantime just give yourself time. I hope you have some support around you. Please take care. Thinking of you x

[Hidden]

I am so sorry, I have no wise words of advice just want to send you a huge hug xx

[JA-fnuk Partner Nurse Fertility Network UK]

Sending you a big hug and good wishes for the future . Take care of yourself

Janet

[Marisa32]

So sorry 😞 not much advice appart from PGA testing embryos. Seems like you used different donors but not sure if you are using the same sperm. Maybe something wrong with the sperm?

[MyLittlePinkness]

Have you had your nk cells tested? I had 4 transfers of (donor) pgd tested embryos,7 embryos transferred, all early chemicals , like you lining, progesterone was always great. On each transfer I had Intralipids, steroids , Clexane, aspirin. I had ERA/EMMA/ALICE, all clear, hysteroscopy to check for anything in the womb, polyps etc, all clear. I tested my natural killer cells and they were high, not very high I might add. For my last transfer I took hydroxichloroquine for aprox 8 weeks before transfer to reduce my nk cells, also taking steroids, Clexane and aspirin. This time little baby girl stuck and I‘m 34 weeks. I feel so sorry for you and am so sorry you’re going through this, there are barely any words that will comfort enough. It’s a hideous journey. 💕💕 I would say that because they are donor eggs (and yes it’s not the miracle we‘re led to believe) I would really think that some of the 7 were probably normal and should have stuck so I would think maybe it is your nk cells rejecting them. It’s just my experience though. I wish you all the luck in the world on your journey 😘😘

[Kimbob82 in reply to MyLittlePinkness]

Hi there, congrats on your successful pregnancy! Can I ask what your dosage of hydroxichloriquine was/is? My reproductive immunologist has just put me up to 2 x 200mg per day… I’ve been on 200mg per day for about 6 months now. I’m hesitant about doubling my dosage but I’ll do it obviously if it is what gets me over the line…

[MyLittlePinkness in reply to Kimbob82]

Hi, yes i was on 2x 200mg. Gosh 6 months is a long time. Have you had any transfers during that time? I was hesitant too about dampening down my immune system at the time (and Covid was still rife) but yeah I would have taken anything! Good luck whatever you decide💕

[Kimbob82 in reply to MyLittlePinkness]

Hi there, I’m not worried about covid. My concern is that I’ve read that it can cause damage to the retina if taken in high doses for too long. Can I ask at what stage of pregnancy you came off it? Sorry for all the questions…

[MyLittlePinkness in reply to Kimbob82]

Hi,feel free to ask all the questions you want! I came off at approx 8 weeks pregnant so 6 weeks after transfer. I also stopped Prednisone at that time too. I didn’t know it could cause damage to the eyes…but honestly I would have taken it anyway.

[Boo718]

Hiya I’m so sorry to read this. This journey is so hard. We had a round with donor embryos we got 3 top quality and when we had them pg tested they were all abnormal 🤦‍♀️ Xxx if you haven’t had them tested I honestly would those three would have just lead to 3 transfers and 3 heartaches xxx I really hope your ok we are all with you. 😘😘😘 xxx

[Hidden]

Sorry 😞. I can feel your pain 😢

[Staceywacey]

Thanks guys for all the lovely comments 🥰I’m going to take some time off I’m so mentally drained from all of this I need a break.

Sending you all lots of love & luck 🍀

[Rowan80]

Taking time out sounds like the perfect thing to do. I know exactly how you feel . Sending love xx

[Shirazlover2013]

Hi Stacey, I’m so so sorry to hear you’re going through this again. It’s so unfair the repeated failures 😭. Your exasperation literally jumps off the page, you are trying so bloody hard. I empathise with trying to solve the mystery of why embryos are not implanting and the impact of BFN after BFN, it’s slowly soul destroying. Yet remarkably we pull ourselves up again and put one foot in front of the other. You know how best to soothe your aching heart, take care of yourself. Sending lots of love xx

[Cinderella5]

Im so sorry Stacey, massive hugs.xxx

[jengi]

Devastating. I’m so sorry, life is so cruel. Sending big hugs Xx