Has anyone had successful implantation from a fresh transfer with stage 4 endo?

[Roobs33]

Hey,

I’m gearing up for my second round starting in June and feel like I need to make a few big decisions very soon about what will happen.

My first cycle I got 2 out of 6 eggs to blastocyst stage. One fresh transfer (failed) and second frozen transfer (missed miscarriage at 6.5 weeks).

My Dr. has suggested to keep the next round almost the same but to add in something to help me hopefully get a few more eggs than last time. She has suggested that I could have the EMMA test but was not sure if I actually needed it. She’s put me on canesflor pessaries anyway to help. Has anyone had this test and was it helpful? I wish they would say you need this rather than getting me to make the decision.

And then as the post title says.. has anyone had success with a fresh transfer with stage 4 Endo. My body was extremely inflamed and I had quite a lot of pain during the stimulation process - and so I wasn’t surprised that it failed as my body was in such a state. The dr has said it’s up to me if I freeze all instead. They have said it could be the endo that perhaps produced something in my body that the egg didn’t like but there’s no way of knowing of course. I just wondered if it had worked for anyone? As obviously everything will be prolonged if I decide to freeze all.

Im just really feeling like I can’t make decisions at the moment. I’ve been trying to find advice online but keep getting mixed outcomes and changing my mind a lot. The test is about £900 so if I really don’t need it then I’d rather not have to get into more debt.

Sorry for such a long post! Also just to add, I’ve had all endo removed apart from on the uterus tethered to bowel - but they said this shouldn’t affect anything. I also have a 4 year old that I conceived before I knew I had awful Endo. I also only have one working tube left.

Sending everyone support on their journeys. Xx

[JA-fnuk Partner Nurse Fertility Network UK]

Maybe you should have a look at HFEA website ''Treatment Add Ons '' and see what they recommend hfea.gov.uk Thinking of you

Janet

[Roobs33 in reply to JA-fnuk]

Thank you, will take a look. Have a lovely bank holiday x

[Sunflower35]

No experience with the EMMA test… My bigger concern was egg quality/sperm quality. I have endo stage IV and I have only had 2 transfers, 1 fresh (chemical pregnancy) and 1 medicated frozen (currently 14 weeks). I did the medicated frozen to better control my fertility window.With regards to pain, I have been feeling all kind of random pains though the treatment and in the early weeks of pregnancy (now much better!) but I felt I couldn’t control the pain situation in that early stage as it’s not like endo would go away without surgery… Having said that, perhaps a frozen transfer would give your body a bit of time to recover if you feel extra unwell during egg collection and better control your fertility window? Can you perhaps make a decision after egg collection? Knowing how I felt after egg collection, I’d find it hard perhaps to pass on the chance of a fresh transfer, but you cannot tell how you’ll feel until you are in the moment. Sorry if it is not helpful…

[Roobs33]

Heya, yes it’s definitely helpful- thank you 😊 so pleased for you and I hope that everything goes smoothly for you ❤️ Yes you are right, I guess I will just need to see how I feel after egg collection and should just stop worrying about it until the time comes. I think I’m just so desperate for it to work next time (as everyone is) that I don’t want to put a foot wrong. I hate that everything is so beyond our control. I’m on a load of supplements recommended by a fertility and Endo specialist so I guess there’s not much else I can do at this point. Thanks so much for replying and have a lovely weekend xxx

[WeeJacs]

Also no experience with EMMA but I have endometriosis also. Have you read is my body baby friendly? Dr Beer’s it’s excellent after reading this we decided to go for immune testing plus nk uterine biopsy as endometriosis is linked to inflammation as you know. We’ve had several miscarriages so thinking it’s either my egg quality or an immune issue. Getting the results next week x

[Roobs33 in reply to WeeJacs]

Thank you so much for your response and for the book recommendation. I will definitely take a look at it. I’ve been wondering about NK cell testing and did mention it to the nurse. She said I could bring it up in my nurse consultation but that the Dr hadn’t suggested it. When I brought up about the extent of my inflammation during the fresh cycle and how I thought that it definitely had a negative impact on the implantation she said it could have been. She said that they aren’t sure if endometriosis releases any sort of toxins but it’s likely that it could. I just hate the not knowing what is causing it. I really hope you get some answers when you get your results through and I’m sorry that you have gone through several miscarriages. It’s so so difficult and I hope that you have lots of support. I really wish you the best of luck going forward. X

[WeeJacs in reply to Roobs33]

Definitely get the book if you can, it really is an eye opener. Thank you, you too such a hard journey. Nearly 10 years now for us but not ready to give up yet xx

[Doglover5]

I had success with a fresh transfer with severe endometriosis. It had been excised 6 months before though. From my research, active endometriosis can affect egg quality in a fresh cycle but should not impact a FET so once the embryos are created you should have the same chance as a non endo person in a FET. Hope that helps. Good luck xx