What trigger did you use?: Hi ladies... - Fertility Network UK

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What trigger did you use?

Millbanks profile image
51 Replies

Hi ladies, just wondering what triggers you’ve used and if you’ve had any issues ? I’ve been prescribed Gonasi 5000 and am worried it won’t be strong enough. I’m quite petite so not sure if that makes a difference... xx

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Millbanks profile image
Millbanks
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51 Replies
hifer profile image
hifer

Hey lovely. Always used Ovitrelle (also used this for my trigger for transfer). Couldn’t tell you how much I had to take for EC. I don’t know how you’d tell if you had had problems with it or if it wasn’t strong enough...What are your concerns hun? Xx

Millbanks profile image
Millbanks in reply to hifer

Thanks lovely. So I’ve had a Gonasi 10000 trigger before at another clinic and we only got half the eggs out, the rest didn’t release. But I don’t know if that was just a fluke.... I’m now paranoid that 5000 isn’t enough. Although I was on different stims so maybe that has an effect? Xx

hifer profile image
hifer in reply to Millbanks

Oh right. I’ve not heard of this before. I understand why you have concerns now. Oh my god there are just a zillion things to worry about! Have you discussed with your clinic/ consultant? Perhaps they can reassure you? Xx

Millbanks profile image
Millbanks in reply to hifer

Honestly!! Isn’t there always something! I did explain my concerns and they said there is no reason for it not to work. It’s standard amount.... so I have to just trust them but feeling anxious! Xx

hifer profile image
hifer in reply to Millbanks

Ok good. At least you have discussed with them. I know it doesn’t always alleviate the anxiety though 🤦‍♀️. I’m sure the combo of the trigger with different stims will do the trick 🤞. Hopefully you can get reassurance from others on this thread too . Sending hugs 🤗 xx

Millbanks profile image
Millbanks in reply to hifer

Thanks lovely. Always good to hear your voice of reason! Hope you’re doing ok and all progressing nicely xx

hifer profile image
hifer in reply to Millbanks

I know it’s just so hard when there are so many things to worry about. Everything crossed for you hun. All fine here thanks 😘xx

Maui2020 profile image
Maui2020

Hey lovely, as far as I know the trigger amount can depend on the number of follicles. So larger number of follicles require a higher trigger.I’ve only ever had buserelin 0.3 (disaster-only a fraction of eggs mature), buserelin 0.5 (worked wonders) and double dose ovitrelle (gave me OHSS but worked).

Could you ask your Dr their opinion on why the 10000 trigger could not have worked previously ? Could your follicles are more mature before trigger this time? I understand the worry as the trigger is the last step in success. I also know there comes a point we have to relax and trust the process. It’s so hard though ❤️❤️

Millbanks profile image
Millbanks in reply to Maui2020

Thank you - that's good to know. I had a low number of follicles this time so maybe that's why they went low. Although the first time I had 20 and they used Buserelin 1ml and that worked fine - apparently there's no difference except if you're planning to do fresh vs FET...I'm afraid I've left it way too late as triggering tonight - I've dithered like an idiot and now panicking!! I think I just have to trust them 😫

How are you getting on? xx

Maui2020 profile image
Maui2020 in reply to Millbanks

The whole thing is just a horrible anxiety filled process as it means so much to us. But remember something gave you comfort with what the Dr said at the time.. anything after is just our heads thinking the worst. So absolutely just trust their process now. I always find trigger evening a relief as its such an achievement to get to the stage.. so well done for that!

I’m ok, thank you for asking xx But honestly, I’m not feeling the most positive. Absolutely no symptoms whatsoever 3dp, planning on keeping myself busy until OTD and hope for a miracle xx

Millbanks profile image
Millbanks in reply to Maui2020

Ugh isn’t it just. Thank you. It does make me feel better. If I hadn’t had a bad experience I wouldn’t even think about it. Yes I just want to take the shot and not think about it anymore!!

Aww I know what you mean. There is no reason to think it won’t work (ha, never take my own advice).... and no symptoms are fine. I honestly think that we are so in tune with it we notice the tiniest of things when if it was just a week or 2 after having sex you wouldn’t notice a thing... I have everything crossed for you lovely xxx

Maui2020 profile image
Maui2020 in reply to Millbanks

So true that we feel like we need to experience something to know it worked. Even when I know that doesn’t make sense!

I think all of our bad experiences add that layer of stress but think of it as if you’ve already done the trigger so it’s all out of your hands anyway. Fingers crossed you’ll get a fantastic result. Will you opt for a fresh transfer aside from the PGS etc? X

Millbanks profile image
Millbanks in reply to Maui2020

Yes exactly!! Argh!!

They really do add layer upon layer of stress. Gosh it’s just not easy 😔

No we didn’t want to do any more transfers until we’ve done the testing and my immunology is back... so we’ll freeze all xx

Maui2020 profile image
Maui2020 in reply to Millbanks

Good plan. Wishing you all the luck for EC! And celebrating the last of the meds for awhile yay! X

Millbanks profile image
Millbanks in reply to Maui2020

Thank you lovely one. I cannot wait for a glass of wine 🍷.

Will keep my fingers crossed for you this week. When is OTD? Xx

Maui2020 profile image
Maui2020 in reply to Millbanks

Oh the between cycle perks.. I love every one of them. Enjoy it! My OTD is next Friday 16th.. I toyed with early testing but I find POAS so distressing now that I don’t think I want to do it multiple times. Distraction is my tactic this time! X

Millbanks profile image
Millbanks in reply to Maui2020

Ha I know! The bar for enjoyment is pretty low at the moment so we have to enjoy what we can!

I hear you. It’s so traumatic. Last time I just wanted to wait until my bloods because I just couldn’t cope with the shaking hands, the sweating and the heart rate at 100mph... I found last time what helped me was not thinking ahead at all. Literally just one hour at a time. Xx

Maui2020 profile image
Maui2020 in reply to Millbanks

I’ll take that on board, anything that helps.

For me it’s also the pressure of FMU, I haven’t had time to psyche myself up or calm myself into a serene “what will be..” mood. It’s always following a sleepless night with a now or never moment. Can completely relate to the heart rate and shaky hands.

Hoping the next time will be better for us both xxx

Millbanks profile image
Millbanks in reply to Maui2020

I totally understand. I’m also the same - sleep gets gradually worse the closer I get to test day..

so usually as soon as I have a transfer I’m dreaming about how I’m going to emotionally tell people that I’m pregnant but last time I stopped myself doing anything like that and it really did help.

Yes everything crossed xxx

Millbanks profile image
Millbanks in reply to Maui2020

Thinking of you today. Xxx

Maui2020 profile image
Maui2020 in reply to Millbanks

Oh thank you xx. Stark white again. Was very detached about it this time and expecting the worst. Made it easier than the times I’ve got my hopes up but it chips away each time. I feel so hopeless and fed up 😔

Millbanks profile image
Millbanks in reply to Maui2020

It’s so unfair. I feel for you. It’s an absolutely hideous feeling. No one deserves this 😔 But we know it passes and you will gather strength again, I just know it. Sending lots of love for now xx

Maui2020 profile image
Maui2020 in reply to Millbanks

I appreciate it xx I’ve also learnt this cycle that thinking the worst is not a nice head space to be in. So I will try and be more positive. Have one more embryo to try. How are you getting on? Xx

Millbanks profile image
Millbanks in reply to Maui2020

It’s an almost impossible balance to strike between hope and self preservation.... that’s great that you have one more. This could be the one!!

I’m just waiting for our embryo update tomorrow. Hoping for a couple so we can crack on with PGS.. xx

Maui2020 profile image
Maui2020 in reply to Millbanks

The stories where people have said their lowest grade was their normal PGS is what I’m repeating in my head. This is why this forum is so amazing. And thank you for letting me share my live update of feelings with you as I know you understand.

Really hoping you get some great news and it all lines up perfectly for your next attempt xxx

Millbanks profile image
Millbanks in reply to Maui2020

I am also holding on to that! Most of the frosties we have are low grade so we'll be testing all those - fingers crossed hey! I love those stories too - they give me hope. I just know it will happen for us both :)And you are so welcome - please message me anytime!

Yes I'm hoping so - but we'll keep on trucking regardless because that's what we do - we are amazing and strong xx

Maui2020 profile image
Maui2020 in reply to Millbanks

Yes we are absolute warriors! X

KiboXX profile image
KiboXX

I’ve always found a double trigger works better for me with giving eggs a final boost in terms of quality. Could you ask for a double dose? I had one dose of gonassi on my last round and one dose of buserlin instead of a double of gonassi xx

Millbanks profile image
Millbanks in reply to KiboXX

Thanks lovely - I've never used a double before - gosh it's a minefield!! It's too late now unfortunately as I trigger tonight but I was looking for some reassurance that 5000 Gonsai has worked for someone!!Hope you and the little one are doing well xx

KiboXX profile image
KiboXX in reply to Millbanks

It is!! I definitely had a 5000 gonasi on my successful round. Got everything crossed for you for your collection ♥️🤞🏻 xx

Millbanks profile image
Millbanks in reply to KiboXX

Amazing - you've made my day!! Fingers crossed :)Lots of love to you xx

yellow987 profile image
yellow987 in reply to Millbanks

Hey! I had a 5000 gonasi trigger too. I was supposed to have 10,000 but it was reduced it at the last minute to 5,000. Had a textbook EC with it... transfer didn’t go quite so well 😬😆 but the EC with the 5000 gonasi trigger did. You have got this, good luck!x

Millbanks profile image
Millbanks in reply to yellow987

Oh brilliant. Thank you! Can I ask why they reduced it? Sorry to hear the transfer wasn’t good 😔 xx

yellow987 profile image
yellow987 in reply to Millbanks

Thank you! There is always some unexpected surprise for us isn’t there?! Sure, during the latter part of stimming, I started to show some early signs of OHSS so they reduced my menopur dose gradually in the last couple of days to prevent it from kicking in. The reduction of trigger was for that reason too, I think?? I see you said you are petite, not sure if / how it makes a difference but for information I am 5”9, normal BMI for my height - so not petite and that trigger still worked well x

Millbanks profile image
Millbanks in reply to yellow987

Always!!

Ah I see, so that makes sense. And that does help! I’m a wee 5”1 so I hope it’ll be enough xx

Hopeful80 profile image
Hopeful80

Hello I only saw your post now I'm on 10000 gonasi as I have low AMH

I think 5000 is given more frequently though as I remember asking at my Clinic on my first round.

I know it is hard but we have to trust the clinic too they have loads of experience.

Best of luck with egg collection xx

Millbanks profile image
Millbanks in reply to Hopeful80

Thank you! I know, it’s so hard to relinquish all control but I’m sure it’ll be fine.

Good luck to you too!! Xx

Hopeful80 profile image
Hopeful80 in reply to Millbanks

Just wanted to wish you all the best with egg collection tomorrow.They scanned me this morning and the follicles were still there so I went for egg collection.

They got 4 eggs so now hopefully they fertilised.

Xx

Millbanks profile image
Millbanks in reply to Hopeful80

Oh that’s great! Well done ☺️ fingers crossed for your fertilisation!

And thank you! Xxx

BBHH1 profile image
BBHH1

10000 of HCG and Lupron. Double trigger to try to increase number of eggs for dimished ovarian reserve

Millbanks profile image
Millbanks in reply to BBHH1

Thanks for your reply. That’s good to know x

Rain415 profile image
Rain415

I was prescribed 10000 gonsai and I'm like you a mere 5ft (they said 4ft11 but I'm choosing to not beilive them and think that I have reached 5ft haha) but after my final scan rang me to say 5000 because they worried 10000 would have been too much. It was fine for me, hoping it all goes smoothly for you! X

Millbanks profile image
Millbanks in reply to Rain415

Haha I always cling on to my extra cm too 😘

That’s really good to know - thank you! I feel a lot better about it now xx

Liv91 profile image
Liv91

Hi I had 5000 gonasi, they retrieved 14 eggs and 4 made it to blastocyst, I’m currently In 2ww. Try not to worry, I hope everything goes well for you 🤞🤞🤞 xxxx

Millbanks profile image
Millbanks in reply to Liv91

Thank you! Good to hear it was successful! Best of luck for your 2WW xx

I was always Gonasi but 10,000 xx

hoping2021 profile image
hoping2021

Just wanted to wish you all the best and lots of luck Millbanks 😊 xx

Millbanks profile image
Millbanks in reply to hoping2021

Thank you lovely xxx

Nuszkahope profile image
Nuszkahope

I have used Decapeptyl as my triggers to minimise the risk of OHSS as I always had plenty of eggs. I seriously would not worry though, I am sure your doctor prescribed the medication that will work for you x they know what they are doing x try not to worry. Good luck x

Millbanks profile image
Millbanks in reply to Nuszkahope

Thanks! I split some of the trigger so only got 70% and it still worked ok! Got 14 eggs - phew x

Nuszkahope profile image
Nuszkahope in reply to Millbanks

Great! Good luck 🤞

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