Hi everyone I am wanting to try prednisolone if the clinic's let me (due to covid) for my next IVF round and I was just wondering what doses of prednisolone you were put on?
The reason I ask is because I am between two different clinic's (don't ask lol) and one has advised putting me on 10 milligrams and the other one 20 milligrams so I just wondered what other people have been put on??
I have had 4 previous failures hence wanting to try this and I've had a blood test saying I've got slightly high killer cells.
Thanks
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Flora14
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Hey, I’m on 10 mg. First time I’m taking this, no blood tests to confirm anything, just another thing to try (7th FET, don’t ask! But have a girl from second fresh cycle). Good luck with your cycle!
It was their suggestion. I’m in Denmark. Covid is less severe here and I didn’t know it was an immunosuppressant when I said yes or else I might’ve challenged them 😂 It was purely on the basis that sometimes it helps for people with recurrent implantation failure...
Hi, I am currently 19 weeks pregnant through my 6th FET/2nd egg retrieval with a new clinic. I also wanted and directed my RE to put me on prednisone (and intralipids). I was not tested for NK cells (not offered by any lab/clinic in my country) but I have Hashimotos and had 5 failed previous FETs (not sure if they were all euploid but they were all high quality embroyos so there is a chance that some were normal) My new RE is amazing and listened to my concerns and agreed. I was put on 20 mg and will be tapering off this week so that I stop at 20 weeks. Since you have confirmed NK cells I would personally advocate to be put on 20 mg. I do think my clinic has gone a little overboard with keeping me on prednisone for 20 weeks as I noticed that most clinics only keep patients on til the end of first trimester if that. Good luck with everything!
Thank you this is good to know. I can tell the consultants are getting annoyed with me questioning them all the time lol so I just wanted to see the dosage other people that been put on it seems that it's a mixed between 10 and 20
Cinderella or me? Lol I think you mean cinderella. Mine are slightly high apparently but be good to know cinderellas .its seems its a mix between 10 and 20 just not sure which is more appropriate for me and I can tell my consultants are getting pissed off with me questioning them all the time lol
Good to know both!! I'm starting to suspect that mine might be a little raised - my mum has psoriasis and apparently if there is autoimmune issues in your family then it can be an indicator that you could have some higher levels of NK - BUT I didn't have them tested when I had my ERA because my consultant doesn't believe in them as an issue. Now I'm wondering if I should have. Dammit! xx
My clinic weren't convinced by the prednisolone but I pushed and they let me take them. They were more for intralipids but I had more faith in medication than intralipids. I had a load left over from being abroad as you can buy them over the counter so just went ahead and took them this cycle without asking really....bit naughty but hey ho.xxx
No, it wasnt with the ERA. I had a shed loads of biopsies taken when I had my hysteraocopy in Athens ages ago along with a huge loads of bloods which are like the Chicago bloods and it was discovered then, not high only slight raised. I was also queried for an allery to the sun which maybe similar to lupus so thought there may be some autoimmune stuff going on too. I know clinics arent keen to give these out due to covid, it was hard enough to get them precovid. Keep pushing and begging them.xxx
Interesting! My clinic are really resistant to them at the best of times, and at the moment pretty opposed! I will see though, I could at least have a blood test I guess. x
Cinderella so you are only slightly raised and recommended 10mg? Your comment about an allergy to the sun is mega interesting to me a few years ago and now in the summer my feet go really red and swell in the sun and I get a rash if they are in the Sun for too long it first happened when I was on holiday. I wonder if this is an autoimmune thing? Don't really understand what the autoimmune conditions are lol. What's classed as an autoimmune condition? I have to take antihistamines to control the rash. This is maybe even more reason for me to be on the steroids as maybe there is a link! I also have a skin condition called dermographism which is an over-the-top immune response if I scratch myself I come up really badly and look like I've been attacked lol.
Lol I am considering getting someone from abroad to get me them if they don't let me which I know it's bad. I am considering taking intralipids as well but like you I have more faith in the steroid medication and obviously it's much cheaper why wouldn't you try something so cheap first and easy to do. It does really wind me up that some clinics will let patiets have them regardless of having any test done "just in case " yet other clinics won't even let you have it when you have had tests done. X
My mum has suspected lupus (SLE) and I am the same. I didn't get it until I was in my 30s. If you can get someone to buy you a heap abroad then it's worth a shot I reckon. I know it's a bit naughty to self medicate but when clinics dont support it, then it's down to us I feel. The only thing is to not come off them quickly so if you do start, you take them in the morning as they cause insomnia and when you stop you have to wean off them, dont just stop.xx
I had one previous failure, but mostly I noticed that I was having other kinds of inflammation and thought it might help. I have thyroid problems and even though I tested negative for hashimoto's disease, I had Covid last year and worry about autoimmune and inflammatory problems in general. So I just asked and my doctor put me on it. It made the eczema on my hand go away, so it did do something at least.
I was with Doctor shehata, miscarriage specialist. I had two ivf failures, 2 miscarriages, 3 chemical pregnancies. My dose seems higher than lots of others, but it worked for me x
Hello ladies, i know this is an old post. But can you all kindly share what level your nk cell was at? I did the chicago test and my nk cells was 27 vs normal of 10. When i did the test, I had just miscarried for the third time so just wanted them checked. I am now pregnant again (naturally for the 4th time), but afraid i could miscarry again. My clinic put me on clexane but told me to wait until they give me the go ahead on prednisone (they already prescribed it and i have them at home). I dont know why they said to wait. Im hoping not to do the nk cells test again as its just way too expensive. I am now 4 wks and 2 days and i usually dont get past wk 5 without starting spotting and eventually miscarrying. Please share your no cells level with me and any advice you may have. Shall i just take the prednisone?
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