Disappointing News : We've just had out... - Fertility Network UK

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Disappointing News

Montgomery2 profile image
11 Replies

We've just had out G4M2 Careunity test results back and it's came back negative for the gene mutation that has been found to cause implantation failure and miscarriages.

We have had 4 FET transfers and they've all been negative. We have 2 embryos left to try before contemplating PGS embryo testing on a new batch of embryos.

Can anyone give advice/share experiences of PGS testing?

Thanks

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Montgomery2 profile image
Montgomery2
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11 Replies

I did PGS - I got pregnant, but I miscarried at 8 weeks so it is not a silver-bullet. I am still going PGS though xx

Montgomery2 profile image
Montgomery2 in reply to

Sorry to hear that, How many embryos did you have PGS tested? How many were disgarded?

in reply to Montgomery2

5 embryos tested, 2 discarded - I transferred a PGS normal embryo and still had a miscarriage.....so whilst I would say PGS is worth it, there is no guarantee xx

Lilly12255 profile image
Lilly12255

Hi, could you please tell me more in this test?

Montgomery2 profile image
Montgomery2 in reply to Lilly12255

Hiya its a test my clinic offer. If you Google care fertility unity test it comes up. It's a genetic test to see if you have a gene abnormality that's linked to implantation failure x

Ranchu90 profile image
Ranchu90 in reply to Montgomery2

Did you check if you have blood clotting disorder as well like Factor 5, thrombophilia screening etc., just out of curiousity?I had PGS test done on 5 of our blastocysts and I do not regret for choosing to do that, even the outcome was the same just another biochemical pregnancy. 3 came back normal, 1 mosaic transferrable and 1 abnormal that was discarded. My advice to you is to do another fresh cycle and test all of them in one go, it will save time, money and unnecessary worries. I was also worried that we are not producing chromosome normal embryos after having 2 chemicals but we were wrong. All the best 💓🤗

Montgomery2 profile image
Montgomery2 in reply to Ranchu90

The care unity test is basically testing for sticky blood. We have decided to see how our last 2 embryos go and potentially test the next batch. Our only problem is I had 6 viable embryos on the first round all top grade. The total cost could be £3-4k if we get the same amount of embryos again, which is a big gamble if they all come back normal like every other test we've spent money on so far.

Ranchu90 profile image
Ranchu90 in reply to Montgomery2

Top graded embryos doesn't mean euploid embryos. My 5AA is a mosaic and my 5BC is normal. I prefer to spend my money to have all the tests and after that to try again instead of transfering without having any succes. Testing not guessing 😁 We also did so many tests in the past 5 years and all came back normal. I am planning to have 5 more genetic tests in next coming weeks 🤞🍀I wish you good luck with whatever you decide 🤗♥️

Lisichka profile image
Lisichka

We did PGS testing after 4 failed FETs. Out of 15 embryos 10 were normal and one was a usable mosaic. I am happy we did it because like yourself, we were at a loss as to what else could be wrong. Transfer #5 worked so far with the PGS tested embryo (plus we changed protocol a lot and did ERA, which I see you’ve already done). I think it’s worth doing for sure

Florencehill profile image
Florencehill

Hi Montgomery2, I had 9 good embryos PGS tested and 3 came back with no abnormalities. Im 42. I don't regret spending the money as its another thing to rule out. I dread another misscarriage with an untested embryo so this makes me feel more optimistic but I kbow its not fool proof. X

Montgomery2 profile image
Montgomery2 in reply to Florencehill

Thanks. Our doctor has advised us it will just shorten the time it takes to potentially get pregnant. I'm yet to have a positive pregnancy test at all despite being off birth control for 5 years and 4 embryo transfers. He has left the choice to us but advised to cross the bridge when we get to it. X

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