Need info on protocols: Hi ladies, I... - Fertility Network UK

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Need info on protocols

Lilly12255
Lilly12255

Hi ladies,

I am on my second cycle after a failed one and it’s again only one follicles that is growing. I am wondering whether my doctor is using the right protocol. He did not tell me anything about options of protocols but after googling, I realised that I am on a mini IVF also called mild IVF. I take Clomid for 3 days starting on day 3 of my cycle and a meriofert injection of 150-450mg every other day until egg collection. Could you please tell me about other protocols? What meds are used? From when and what dosages? I read in other posts some ladies had very different results with different protocols, like the short protocol. I am wondering what it is? Thanks a lot

11 Replies
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Short protocol is usually used (or better said in my case) to have less follicles but a better quality eggs.

Lilly12255
Lilly12255 in reply to Ranchu90

Thanks Ranchu. Could you please give me more details on what medication on which dates of the cycle you take for the short protocol?

Ranchu90
Ranchu90 in reply to Lilly12255

Short was something like this: on day 2 started with Menopur 150, on day 4 Cetrotide and I had stimulation just for 8 days, trigger shot Ovitrelle 250, they collected 7 eggs - 5 mature.

I cannot say that the quality of eggs was better than on long protocol.

Lilly12255
Lilly12255 in reply to Ranchu90

Thank you Ranchu. Does it mean that you had menopur injections every other day or just 8 days in a row and then no further injection until day 14?

Ranchu90
Ranchu90 in reply to Lilly12255

I had every day Menopur for 8 days, on 9th day a triggered and 36 hours later I had my egg retrieval.

Hidden
Hidden

I've had two different protocols. Short was: norethisterone to time period and then start menopur on first day of period followed by cetrotide a few days later and buserelin as the trigger before EG. Long was: buserelin from day 21 to down regulate and then start menopur and gonal f on day 7 of subsequent period with ovitrelle as trigger injection.

Lilly12255
Lilly12255 in reply to Hidden

Thank you very much for sharing the details runuphill. Regarding the short cycle: was it daily menopur injections until trigger? How much was the menopur dose? Regarding the long cycle: you started the menopur only on day 7, so you had less injections than in the short cycle as in the short cycle the injections started on the first day?

Hidden
Hidden in reply to Lilly12255

My dose has changed after scans in both protocols. I started on 225 of Menopur in short protocol. Menopur was taken daily until trigger. The long protocol is more injections. At least 50 in my case. It takes up to 6 weeks whereas the short protocol (not counting norethisterone tablets) took less than 2 weeks.

Lilly12255
Lilly12255 in reply to Hidden

Thank you Runuphill. So a long protocol covers 2 cycles instead of 1 as I understand? Was the number of egg/quality better in the long cycle?

Hidden
Hidden in reply to Lilly12255

They put your cycle to sleep so I'm not really sure. No idea what long protocol results will be as I'm still taking the drugs now.

Hi Lilly - just seen your reply to my post. I am short protocol and am on 450 Menopur usually from day three / this is max dose available and due to my age. I did one round of long but it didn’t work whereas short had a much better result and I even made it to blasto round 2 but round 3 some of the follicles responded really quickly so we had less so did a day 3 transfer.

With my long protocol I down regulated with buserelin from day 21 for nearly 2 weeks before I started on the Menopur.

Hope this helps xx

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