Unresponsive endometrium: Anyone been... - Fertility Network UK

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Unresponsive endometrium

Prayingforafamily profile image

Anyone been told they have unresponsive endometrium? I have 4 frozen top grade embryos but my cycle cancelled due to thin lining, after a hysterscopy that ruled out Ashermans I’ve been told my uterus just doesn’t respond to Estrogen. I’m petrified that this is the end of the road.

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Prayingforafamily profile image
Prayingforafamily
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10 Replies
Sayusayme profile image
Sayusayme

Hey how much was your lining

Same as my lining being thin 7.9 mm trilaminal got cancelled so twice

Prayingforafamily profile image
Prayingforafamily in reply to Sayusayme

I could only wish for 7.9. I’m surprised they cancelled if the structure was good. I am a merely 5.5 😔

Sayusayme profile image
Sayusayme in reply to Prayingforafamily

So sorry about your lining...I wish u all the happiness dear.

But I guess this is my last try ....am gonna give up ttc...remain childlesss or surrogacy 😭😭😭

Prayingforafamily profile image
Prayingforafamily in reply to Sayusayme

Don’t lose hope, I have spoke to lots of women who got pregnant on 7mm do yours sounds pretty good. X

Missl73 profile image
Missl73

Switching to a “natural” FET can help. Have you had lining issues in a fresh cycle or only FET? My body doesn’t respond well to synthetic estrogen so my most recent FET we didn’t use it, I had very low dose stims just enough to grow 1-2 follicles and a trigger shot to ovulate before transfer. My lining thickened up just fine on this protocol xx

Prayingforafamily profile image
Prayingforafamily in reply to Missl73

I only got to 6mm on fresh cycle so had to freeze embryos. I will ask this to my consultant though as it may be an option, thanks for your advice x

Orlattc profile image
Orlattc in reply to Prayingforafamily

I’ve just found your post as I find myself in the same situation a year later. How did you get on?

Prayingforafamily profile image
Prayingforafamily in reply to Orlattc

Hi. Unfortunately after trying numerous different approaches including GCSF injections and natural cycles my lining still didn’t get above 6.2, we transferred on this as it was a good structure but unfortunately our last 2 embryos didn’t stick. We are waiting to consider our next options. There are lots of positive stories on here about success with thin linings though so please don’t feel disheartened x

Orlattc profile image
Orlattc in reply to Prayingforafamily

Oh I’m sorry to hear that. Wishing you lots of luck x

BBHH1 profile image
BBHH1

What did your provider propose?

I think some woman have success with PRP injection in the endometrium. You might want to look it up. Best of luck

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