Zoladex, add back HRT and CHRONIC PAIN! - Endometriosis UK

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Zoladex, add back HRT and CHRONIC PAIN!

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4 Replies

Hi all, first time here so thank you for any help!

I had my first Zoladex injection a week ago and was also given Evorel 50 patches and Utrogestan to take to assist with the side affects.

I am in agony! The joint/bone pain is getting worse each day and I’m totally shattered.

Is the pain from the zoladex or is it from the Add back?

Anyone else has this issue or know on what I can do to improve/stop the pain?

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4 Replies
SoJo_EndoUK profile image
SoJo_EndoUKModeratorEndometriosis UK

Good morning, ouch I’m sorry you’re in so much pain. I’ve not had Zoladex but I have had decapeptyl which works on a similar principle. After my first injection I was in a lot of pain for a few weeks whilst everything was adjusting, after that the pain subsided and I felt the benefit of not having Endo pain every single day, but if you are at all concerned please call your GP for advice. I also use Evorel patches and they are the best HRT I’ve had prescribed to date. Often without add back HRT you can get very unpleasant side effects. I have attached the information Endo UK have produced on treatments, such as the hormone treatments GnRH analogues you are currently receiving. For the pain in the meantime be kind to yourself, hot water bottles, baths, rest, and pain relief (if you can take it).

endometriosis-uk.org/hormon...

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seedhousel in reply toSoJo_EndoUK

Thanks for the reply.

The pain I’m getting is not endo pain, it’s neck, spine, shoulder pain - basically any joint/bone in my body aches!

Maybe I need a higher dose of Evorel?

SoJo_EndoUK profile image
SoJo_EndoUKModeratorEndometriosis UK in reply toseedhousel

Hi Seedhouse,

I experienced the same pains but if you are at all concerned then definitely speak to your GP. I’m sorry you’re going through this I know how rough it can make you feel. 🥲

635703 profile image
635703

I am so sorry you’re experiencing this…..it seems so unfair. It does settle but it’s really scary 😭 I have zolodex and tibilone and had something similar to you but much much milder.

The GP is the best thing! Ask for something to help it settle. Once again so sorry you’re experiencing this 😭 I hope it stops quickly and it’s so infuriating the Endo pain goes but something else comes - 😤😤😤😤😤😤🤬🤬🤬🤬🤬

So much love for this awful time 💕💕💕💕💕💕💕💕💕💕💕💕

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