Memory loss and zoladex: Hi everyone, Has... - Endometriosis UK

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Memory loss and zoladex

Holly12345 profile image
9 Replies

Hi everyone,

Has anyone felt like their brains are not how they used to be before starting zoladex or is it only me? I feel so detatched from myself, I can never remember anything and its effecting my life and job :( I have stopped the zoladex now due to it causing ostepoporosis but I just wondered if your brain recovers or is it fried for life! It’s the most fustraiting thing, I sometimes even forget what I’m saying mid sentence... i’d love to hear your stories

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Holly12345
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9 Replies
Yalda profile image
Yalda

Hi Holly12345, yes had exactly the same problem. I had to stop after 3rd injuction. At that time I was stadying and on my exam I couldn't remember anything I revised the night before. Also I found that the Zoledax injuctions made me to react slower forexample if I wanted to break on the red light, it would take a few seconds longer to react. I couldn't carry on with the injuctions and sttopped them halfway through the treatment. Feeling better but the pain has returned. 😥

Holly12345 profile image
Holly12345 in reply toYalda

Yes 100% feel the same as you! Hopefully it improves now ive stopped taking it! I’m so sorry your pain has returned, wish you all the best ❤️

Joanne-L profile image
Joanne-L

Hi Holly!

I was on Zoladex in 2016... I stopped after the third one! I did not get on with it at all! Felt like my brain wash a mush! Couldn't concentrate! Mood swings galore and just hated everything!

I definitely felt much better once it come out ny system!! X

Holly12345 profile image
Holly12345 in reply toJoanne-L

My brain is so foggy to! Feel nothing like i used to :( x

NoEndoInSight profile image
NoEndoInSight

Hello again Holly12345,

I suffered pretty bad memory problems on Prostap (another GnRH analogue). There is a UK doctor called Dr Michael Craig who has carried out research on the issue. If you google you can access summaries of his research articles like this one:

researchgate.net/publicatio...

His research only covers 6-month licensed treatment protocols or shorter, but the hope is that memory function recovers over time once GnRH treatments like Zoladex or Prostap end. It can take a while for things to improve after you stop the injections, but fingers crossed you’ll be feeling a bit more like your old self before too long, x X x

Holly12345 profile image
Holly12345 in reply toNoEndoInSight

Thank you for the information and your reply! Interesting that this is never mentioned in the side effects! Xxx

NoEndoInSight profile image
NoEndoInSight in reply toHolly12345

Some of the manufacturer leaflets have a warning about “cognitive impairment”, but that’s a pretty vague term and not particularly helpful. Glad the info helped & all the best, x X x

Egec87 profile image
Egec87

Holly12345 how long were you on it for? I'm due to get on Zoladex this month for up to 3 months but I'm really worried about all the side effects I'm reading about.

Holly12345 profile image
Holly12345 in reply toEgec87

Hey was on it for 3 years, everyones different but i haven’t had the best luck, my memory is getting better now but ive been left with osteoporosis, if they keep you on it long term, PUSH for a yearly bone scan, i was told i was meant to have one every year ( after 3 years of not having one) X

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