Endometriosis UK
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Side effects of the Progesterone Only Pill : Cerelle

Hi There, I was recently given Cerelle to take to help with heavy periods, combat oestrogen level and thus reduce pain and discomfort caused by Endometriosis. I read the info sheet that came with it. However I have experienced weight loss and joint pain. I am losing about 1lb a day. Cerelle if anything is meant to cause weight gain not loss. Has anyone else experienced this?

3 Replies

1lb a day is a lot. I'd definitely talk to your doctor about that.

My own experience with progesterone pills wasn't great - lots of headaches, and some weight gain and fatigue. However, they were effective in dealing with the heavy periods and out-of-whack oestrogen. But that level of weight loss sounds unhealthy, so I'd speak to the doctor.

Good luck.


Thank you.x


I've only just joined this 11 months after your posting so I hope you found your answer. For the record here, I have been on Cerelle for 3 months and am suffering from acne, period pains but no bleeding, heightened appetite so weight gain (weight loss would be fab! But not at the rate you are experiencing, on a more serious note). I also have mood swings but I had those with my periods before Cerelle and external forces (e.g. roller-coaster love life affects that greatly anyway!). I'm 53 years old and have no signs of peri-menapause . . .


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