C-Peptide - Normal value

[rvsiv]

Dear all,

C-peptide test shows nomarl value 3.91 ng/ml . normal range 1.1 -4.4 (fasting)

but still BS level is high . Is it means that insulin is not working in body even afte producing enough by pancreas.??

thanking you in advance for your thoughts..

take care.

[namaha Administrator]

If you could tell us some more back ground, it would be helpful to give our thoughts:

Your age, weight & BMI ?

Since when you are diagnosed as T2 ?

Are you on any medication ?

How much is your fasting , PP & HBA1C?

What diet you are taking ?

[rvsiv in reply to namaha]

Dear Sir,

it was a general question.. if c-peptide shows normal value and the person is diabetic, what exactly it means?? Insulin production is fine.. but why blood sugar not in control?? my doubt is that whether produced insulin in not having its quality>> or body cell is not using this insulin available??

just a thought process to see ..

thanking you.

[namaha Administrator in reply to rvsiv]

In that case, the possibilities are :

(1) the affected person is likely to have strong Insulin Resistance !

(2) He is also likely to be an obese

Perhaps , a lot of physical exercise, weight reduction and proper dietary modification could be of help to ensure that the cells take up the blood glucose

He should also consult a doctor to test all other parameters !

[rvsiv in reply to namaha]

Thank you sir.. a good thought..

[sandybrown]

You need to put this question to a medically qualified person!!

[Ralh]

Yes, it seems your Pancreas is OK, but consult medical expert.

[sandybrown in reply to Ralh]

Hello,

How did you get to this consultation? Full method will be helpful not just the answer!

[barani19 Administrator]

rvsiv ,

In normal individuals, the molar ratio of C-peptide to insulin in the fasting state is usually 5:1.

[sandybrown in reply to barani19]

Hi,

I always read your response to get information and understanding.

When I Goggled for ratio,, I got the following information.

"Definition. Insulin and C-peptide are secreted into portal vein in equimolar amounts, but serum ratio = 1:5 to 1:15 due to removal of approximately 50% of insulin from blood during initial passage through the liver. ... Normal range: fasting molar ratio insulin to C-peptide = 1.0."

A bit confused!

[barani19 Administrator in reply to sandybrown]

sandybrown ,

Sorry for not clearly explaining the same.

Since the half-life of C-peptide is longer than insulin, its levels in the blood are always higher than insulin, making it a more reliable measure of insulin production.

Let me take an example of my blood test readings taken in last November.

1) C-peptide (CLIA)[fasting] - 1.93 ng/ml (bio ref level: 0.81- 3.85 ng/mL) or 229.7472 microunits/ml

2) Fasting serum insulin (CLIA) - 19.50 microunits/ml (bio ref level: 2.00 - 25.00 microunits/ml)

So, C-Peptide to Insulin ratio is 11.78. I'm unsure of molar ratio still. If some one could enlighten me that would be helpful.

Conversion used: 1 ng is equal to 0,1190 IU or 119.04 mIU.

Let me know if you need any further information.

Thanks

[rvsiv]

Dear Team,

Thanks for your responses.. be with u always..

Take care.

regards

rvs

[ThreeSmiles]

Please don’t be sarcastic fatbuddy. It doesn’t fit well with this forum which is surely meant to be a friendly place to come to.

And please don’t try and tell me you weren’t being sarcastic.