glimepiride (amaryl) or / and vildagliptin(galvus) instead of metformin

[controlcause]

Did anybody experience iron and Vit D depletion with metformin and used amaryl and galvus(vildagliptin) successfully

[edison]

Yes

I have been a victim and no doctor was able to find out. After 3 years of suffering I am now on to lantus injection.

[controlcause in reply to edison]

yes i was about to start lantus but gp said some side effects so continued meformin .now trying amaryl

[nyonyo in reply to controlcause]

what are the side effects that s/he mentioned? is this about lantus or insulin injection in general?

[controlcause in reply to nyonyo]

i think it was kidney or liver related complications i do not recollect exactly as it was almost 2 years

[nyonyo in reply to controlcause]

Ehm...insulin is injected subcutaneously, how could it possibly affecting kidney and liver? Unlike pills, insulin doesn't go through GI tract and get absorbed by kidney or liver

[controlcause in reply to nyonyo]

Not sure if it was for Lintus or insulin or victosa or another option (i forgot the name) diabetologist suggested but GP turned down . GP knows my body for years so went with her decision

[gangadharan_nair]

In people with Type 2 diabetes who take metformin therapy, serum folic acid levels decrease 7 percent and vitamin B12 levels decrease by 14 percent. B12 and folic acid depletion also increases homocysteine levels. In addition, metformin may deplete CoQ10, thereby increasing heart disease risk.

[controlcause in reply to gangadharan_nair]

Great information..do you have the study ? My gp is looking for it as well.

[santoshi22]

I developed vitamin b12 sufficiency. VERY traumatic. Now I'm taking metformin+cobalamin

[controlcause]

after stopping metformin my haemoglobin jumped from 10 to 14.2 without any effort . hba1c is 5.2 with 50mg x 2 vildagliptin and 1mg x glimeperide

[manixrosh]

Can anyone say, Is it any complication or side effect for lantus insulin? I m using it for the past 3 years.

[gangadharan_nair in reply to manixrosh]

Common side effects insulin glargine (generic name) lantus insulin (brand name) include low blood sugar, problems at the site of injection, itchiness, and weight gain. Serious side effects include low blood potassium.

Links:-

en.wikipedia.org/wiki/Insul...

medlineplus.gov/druginfo/me...