New Medical Discovery
A team of scientists at the Boston Children's Hospital have invented what is being considered one the greatest medical breakthroughs in recent years. They have designed a microparticle that can be injected into a person's bloodstream that can quickly oxygenate their blood. This will even work if the ability to breathe has been restricted, or even cut off entirely.
This finding has the potential to save millions of lives every year. The microparticles can keep an object alive for up to 30 min after respiratory failure. This is accomplished through an injection into the patients' veins. Once injected, the microparticles can oxygenate the blood to near normal levels. This has countless potential uses as it allows life to continue when oxygen is needed but unavailable. For medical personnel, this is just enough time to avoid risking a heart attack or permanent brain injury when oxygen is restricted or cut off to patients.
Dr. John Kheir, who first began the study, works in the Boston Children's Hospital Department of Cardiology. He found inspiration for the drug in 2006, when he was treating a girl in the ICU who had a severe case of pneumonia. At the time, the girl didn't have a breathing tube, when at the time she suffered from a pulmonary hemorrhage. This means her lungs had begin to fill up with blood, and she finally went into cardiac arrest. It took doctors about 25 minutes to remove enough blood from her lungs to allow her to breath. Though, the girl's brain was severely injured due to being deprived of oxygen for that long and she eventually died.
Microparticle Composition
The microparticles used are composed of oxygen gas pocketed in a layer of lipids. A Lipid is a natural molecule that can store energy and act as a part of a cell membrane, they can be made of many things such as wax, vitamins, phospholipids, and in this case fat is the lipid that stores the oxygen.
These microparticles are around two to four micrometers in length and carry about three to four times the oxygen content of our own red blood cells. In the past, researchers had a difficult time succeeding as prior tests caused gas embolism. This meant that the gas molecules would become stuck trying to squeeze through the capillaries. They corrected this issue by packaging them into small deformable particles rather ones where the structure was rigid.
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