metformin has any side efect

[dixit]

[gangadharan_nair]

Metformin is the only antidiabetic drug that has been conclusively shown to prevent the cardiovascular complications of diabetes. It helps reduce LDL cholesterol and triglyceride levels, and is not associated with weight gain. As of 2010, metformin is one of only two oral antidiabetics in the World Health Organization Model List of Essential Medicines (the other being glibenclamide).

The most common side effects with metformin are nausea, vomiting, gas, bloating, diarrhea and loss of appetite. These symptoms occur in one out of every three patients. These side effects may be severe enough to cause therapy to be discontinued in one out of every 20 patients. These side effects are related to the dose of the medication and may decrease if the dose is reduced.

A serious but rare side effect of metformin is lactic acidosis. Lactic acidosis occurs in one out of every 30,000 patients and is fatal in 50% of cases. The symptoms of lactic acidosis are weakness, trouble breathing, abnormal heartbeats, unusual muscle pain, stomach discomfort, light-headedness and feeling cold. Patients at risk for lactic acidosis include those with reduced function of the kidneys or liver, congestive heart failure, severe acute illnesses, and dehydration.

Sources:--

en.wikipedia.org/wiki/Metfo...

nlm.nih.gov/medlineplus/dru...

medicinenet.com/metformin/a...

[RPTP]

Very informative. i take glyciphage GR-1 in the morning but what i have observed that i do have a problem of gas and bloating thought not to the extreme but it is there more than the normal . I always thought that it is due to quiet gall stones i carry. Is there any way out of this gas and bloating problem. Bloating if it occurs is always in the night.Forgot to mention i take Volix M 0.3 in the night before dinner.

[Caveman1951]

Metformin interfers with B12 metaabolism in the body. Better to take B12 supplement after consulting your medics