trypsin & Parkinson

[Edge999]

I have been diagnosed with Parkinson 2 years now. In 2019 i did a food intolerance test and it was low in trypsin.

Trypsin is a protease enzyme that’s produced in the pancreas. It helps to break down proteins into amino acids, which issues an important part of the digestion process. Could this be related to Parkinsons where amino acids are not broken down properly causing alpha synucleon problems? Couldn’t find much on the internet about it…

Raw and fermented foods are naturally richer in enzymes like trypsin. Some of the best high-enzyme foods include pineapple, papaya, kiwi, ginger, sauerkraut, kimchi, yogurt, kefir, apple cider vinegar, avocado and miso soup….

[Boscoejean]

Dysfunction of Cellular Proteostasis in Parkinson’s Disease

Šárka Lehtonen,1,2 Tuuli-Maria Sonninen,1 Sara Wojciechowski,1 Gundars Goldsteins,1 and Jari Koistinaho1,

ncbi.nlm.nih.gov/pmc/articl...

[Boscoejean]

"Trypsin is an enzyme that can be found in the small intestine, or made from plants, bacteria, or fungus. However, most commercial trypsin is made from the pancreas of livestock. Some vegetarian options for digestive enzymes include:

Fermented foods: Raw and fermented foods are naturally higher in enzymes. Some examples include kimchi, sauerkraut, yogurt, kefir, and apple cider vinegar.

Fruits and vegetables: Some fruits and vegetables contain digestive enzymes, including pineapple, papaya, and kiwi.

Proteolytic enzyme supplements: Some vegetarian proteolytic enzyme supplements are available.

Trypsin inhibitors are substances found in many plants that prevent the digestion of proteins in the gut. Some plants that contain trypsin inhibitors include:

Legumes like mung bean and field bean leaves

Tuberous plants like potatoes and sweet potatoes

Squash like Cucurbita maxima (winter squash) "

[Kscott8]

have you tried taking digestive enzymes before meals? Or proteolytic enzymes on an empty stomach?

[Edge999 in reply to Kscott8]

I have not. Will look into it. Was wondering if it was a red herring or something more to it

[Edge999 in reply to Edge999]

Thanks, thinking it’s worth a shot

[Edge999 in reply to Kscott8]

No

[AGH_1966 in reply to Kscott8]

Have they helped you?

[LAJ12345]

try this

nz.iherb.com/pr/now-foods-s...

[Edge999 in reply to LAJ12345]

Thanks, thinking it’s worth a shot

[Salted]

Have you found that supplementing with enzymes or eating a high enzyme diet helps with symptoms at all?

[Edge999]

not been focused on it. Eating more whole foods and cutting processed foods/carbs/sugars seems to help though

[kruidjenat]

Many polyphenols inhibit pancreatic enzymes. Also mould/mold and pesticides could be hugh factor to disturb liver/pancreatic/intestine function. Maybe you can look further into those issues. I have problems with mold that give a burden on my liver/pancreatic/intestine function. I cannot use fermented foods as they worsen histamine. So I have to avoid polyphenols to help digestion. I also have sulfurintolerance so most digestive enzymes are a problem for me. I slowely switchted to whole foods meatbased as plants has to much polyphenols and moldspores and pesticides and herbicides.

[mk2002wi in reply to kruidjenat]

Can you detail what your sulfur intolerance is about?I have allergic reaction to sulfur dioxide, sulfa antibiotics and even sulfur content in the carribbean ocean.

I am trying to piece together how my PD may be caused by nutritional deficiency or sensitivity to sulfur, etc.

Thanks.

[Edge999 in reply to kruidjenat]

I’ve started to go more ketovore

[Kruidje in reply to Edge999]

If you cannot convert sulfur, you could also have a problem with b1. B1 is needed for parkinson.

[Kruidje]

Hi, when I eat sulfite (on dried fruit or pickled things) or I eat garlic, onion, leek, or other sulfurrich plants, or I use sulfur containing supplements then I have problems. Like more gasproducing (that realy hurts my intestine) and problems with shortening of the muscles. Then I have less supples and the tendons are inflammed because the muscles are shorten. Also it gives brain inflammation. So I avoid the plantfoods high in sulfur. And for the sulfur in meat and supps I help my body with additional supps to support the enzymes who convert sulfur. Also I avoid plants who provide bacterie growth who support hydrosulfide production.