AI's answer: Yes, certain compounds found in Ceylon Cinnamon, particularly cinnamaldehyde, have been shown to inhibit amino acid decarboxylase activity. 1 This enzyme is involved in the breakdown of amino acids, including those that can interfere with neurotransmitter function.
1) journals.asm.org/doi/full/1...
I know AI is not to be relied on as Fact, but I am not sure of the meaning in the linked article.
I will say Ceylon Cinnamon has kept me from having to increase my C/L.
AI making stuff up. What the reference says:
"the possibility that the mechanism of cinnamaldehyde activity involves inhibition ... of biosynthetic enzymes (>7.5 mM, histidine decarboxylase) (29) is unlikely" [emphasis added]
The AI did not understand that the "is unlikely" ending negates what preceded it. The reason for this is that AI is not actually intelligent and does not understand anything. It merely regurgitates likely combinations of words. An up to date example of why AI is not to be trusted.
this study suggested by parkibot.com says yes
sciencedirect.com/science/a...
That says: Of the spices used, cloves, cinnamon, sage, nutmeg, and allspice were very effective in inhibiting the decarboxylases. Among the components of those spices, cinnamaldehyde and eugenol were found to be effective inhibitors.
But this is a March 1995 paper.
No updates or revision of that position since then?
Ai could help if you interrogate it on the latest thinking and experimental work done since 1995.
Nothing stands still. You still have to keep your wits about you when doing research. Don’t allow the ‘Ai’ to put you to sleep 🌹
Edit - Paper Referenced:
To say that AI is unintelligent and just regurgitates words is a common misconception. Yes, it can hallucinate and have bias but it actually does much less so then humans. Prof Geoff Hinton who won the nobel prize for his work in AI explains it very well at his talk here AI is possibly not yet self aware but it is capable of subjective thought!
youtu.be/Es6yuMlyfPw?si=4_q...
It is no misconception that AI regurgitates words.It is a tool that predicts the next word in a sequence based on everything it's read. It usually gets it correct based on probability but It has no conceptual understanding or questioning ability and that is a why as an intelligent human you must question what it gives you.
That’s not how it works - or you could say that is how the human brain also works. As above see the video from Hinton. He won the nobel prize on this so he knows what he is talking about!
That's how AI works. It regurgitates based on what it's been fed. It's good at it as its capable of consuming hundreds of thousands of documents. Some humans are the same and blindly follow what theyre fed, but most humans modify that input with their own questioning thoughts and evaluations.
it’s not that simple. Far more sophisticated! Digital AI is a neural network with balances and weights, and it makes decisions and provides output based on that rather than just regurgitate the next word based on probability. All humans have biases and weights too and we tend to suffer from hallucinations even more than machines as our memory is less permanent. Furthermore it has been shown that machines capable of subjective thought.
It isn't simple and agreed there will be weighting sapplied but the core method is probability based on its feed.
just as a follow up. I’ve also found the latest versions of AI to be capable of original thought. I’ve posed complex problems to It and it has astonished me by coming back with creative and correct solutions, not discoverable on the web. Of course, to get these sort of insights one has to prompt the system with knowledge of the problem that is to be solved in the first place. If you ask a general question expect a general response - but a detailed prompt with clear context can generate an answer that is truly insightful.
Yet in the actual example given it came up with exactly the wrong answer. All of your arguing fails in the face of that simple fact.
“but a detailed prompt with clear context can generate an answer that is truly insightful.“.
Well! I'm puzzled. Here we have an AI that seems to work backwards, the more the contribution of a human intelligence is broad and informed in the prompt the better is the answer of AI. Well thanks! But the answer is not even that good, I read the references and in my opinion these AIs tend to support the interlocutor's point of view. That is, the answer changes depending on who writes and how, as you can also see here,( yes, No,yes, maybe, LOL ). Maybe they understood that this way they sell more.
It would have been better to go out for a walk today too, but it's raining.
Yes, I agree - but because the answer is not always the same one might argue that it is acting more like a human then a computer! Human’s can be highly subjective in providing an answer depending on what is expected of them, context, how the question is framed or simply mood. Maybe AI is similar….if it was all about simple probability one would expect their answers to be very consistent! 😀
Ai search is to be relied on as fact, once a reliable source is linked. All Ai does is automate your search.
What still remains is an evaluation/assessment of what it has turned up.
So you still have to contend with the article contents. And this I will leave to the more knowledgeable members 🌹
What you are saying is you can use AI as a search engine and then only rely on reliable sources (Meaning, Not AI). Otherwise, Bad things like this happen - How to Use ChatGPT to Ruin Your Legal Career:
youtu.be/oqSYljRYDEM?si=1sp...
Personally, I prefer to use actual search engines like Google Scholar, but that's just me.
Nobody uses AI like this way anymore park_bear . Old stuff. Today it's used for studying.
The search engines are already inside Ai. Or is it, Ai in the search engines. Anyway you will not soon be able to delink search and Ai.
Check Perplexity, ChatGPT4.0, Gemini 2.0 in search mode.
The future is already here my friend.
And of course it is going to confuse and befuddle many🌺
Do you take Cinnamon alone, or mixed with something? Do you take Cinnamon alongwith C/L or separately?
hi Gcf51 ,
maybe you had some bacteria eating your C/L that Ceylon Cinnamon killed, IMHO
First time I am using Gemini. Here I use the 2.0 experimental.
The question: Does Ceylon cinnamon inhibit decarboxylation?
Response: There's no scientific evidence to suggest that Ceylon cinnamon inhibits decarboxylation. In fact, the available research points in the opposite direction.
Subheads follow -
Decarboxylation and its Importance
Why Ceylon Cinnamon is Unlikely to Inhibit Decarboxylation
In summary
Important Note
Further Research
Finally Gemini 2.0 Experimental suggest (throwing a little shade on your query)
“It's important to rely on scientific evidence when seeking information about these processes. Avoid relying on anecdotal claims or unsubstantiated online information.”
Not too sure what model you used. But this technology is moving fast. Do use the latest models.
Incidentally the response from ChatGPT 4o matches the response of Gemini 2.0 Experimental.
So who is making stuff up ‘you’ or the ‘Ai’ 🧐
My reply from Gemini 2.00 using a slightly more detailed prompt.
Question: Does Ceylon cinnamon inhibit decarboxylation? Think through this carefully referencing scientific papers from respected authors. If the answer is nuanced let me know but come up with your own opinion based on your findings
Response:
Yes, Ceylon cinnamon can inhibit decarboxylation, but the answer is nuanced. Here's a breakdown based on current research:
What is Decarboxylation?
Decarboxylation is a chemical reaction that removes a carboxyl group (-COOH) from a molecule, often releasing carbon dioxide (CO2). This process is crucial in many biological systems, including the synthesis of neurotransmitters and the breakdown of amino acids.
Cinnamaldehyde: The Key Player
Ceylon cinnamon (Cinnamomum verum) contains a compound called cinnamaldehyde, which gives it its flavor and aroma. Several studies suggest that cinnamaldehyde can inhibit decarboxylase enzymes.
Antibacterial effects: Research by Zainal-Abidin et al. (2013) showed that cinnamaldehyde in cinnamon bark oil inhibits amino acid decarboxylase activity in oral bacteria, contributing to its antimicrobial properties. This is because decarboxylases are involved in bacterial amino acid metabolism and survival.
Neuroprotective potential: A study by Lee et al. (2016) explored cinnamaldehyde's potential in Parkinson's disease. While the exact mechanisms are complex, inhibiting decarboxylase activity is believed to play a role in its neuroprotective effects. This is because the enzyme aromatic L-amino acid decarboxylase (AADC) is involved in dopamine production, which is deficient in Parkinson's disease.
Important Considerations:
Specificity: Cinnamaldehyde may not inhibit all types of decarboxylases equally. More research is needed to determine its specific effects on different enzymes in various pathways.
Dosage: The concentration of cinnamaldehyde needed to achieve significant decarboxylase inhibition likely varies depending on the specific enzyme and context.
Other compounds: While cinnamaldehyde is a primary component, Ceylon cinnamon contains other bioactive compounds that could also contribute to or modify its effects on decarboxylation.
My Opinion:
Based on the available evidence, I believe Ceylon cinnamon, specifically its cinnamaldehyde content, shows promise as a natural decarboxylase inhibitor. However, it's crucial to remember that research is ongoing. More studies are needed to fully understand its mechanisms, efficacy, and potential therapeutic applications.
It's important to consult with a healthcare professional before using cinnamon or any other natural remedies for specific health conditions.
References:
Zainal-Abidin Z, Mohd-Said S, Abdul Majid FA, et al. Anti-bacterial activity of cinnamon oil on oral pathogens. Open Confer Proceed J. 2013;4(2):12–16. doi: 10.2174/2210289201304020012. 1
1.
pmc.ncbi.nlm.nih.gov
pmc.ncbi.nlm.nih.gov
Lee SH, Kim YH, Park JD. Cinnamaldehyde Induces Neuroprotective Effects Against Parkinson’s Disease in In Vitro and In Vivo Models. J Food Sci. 2016;81(8):H1997-2
Beautiful prompt!
You illustrate here that the quality of the prompting - your input - is crucial to the response given by the Ai.
So it is not like MarionP sarcastically suggest that having found AI ‘you can relax’.
We need to treat Ai as a research assistant: cross check what it has produced and asking it to justify its assertions.
Welcome to the brave new world 🌺
Absolutely! It's about the quality of the prompt/questioning generating ideas, and then cross checking/evaluating those responses by using further prompts/questions....
So glad now that you have finally found somebody you can trust...AI. Now you can relax.
Ceylon Cinnamon
Need info 
Cinnamon May Be Used to Halt the Progression of Parkinson’s disease
