Vitamin C + Omega 3 Fish Oil Combo

[JayPwP]

Though not directly associated with PD, PWPs take a lot of drugs and supplements, which may affect the Liver.

From that perspective, posting a rat study:

ncbi.nlm.nih.gov/pmc/articl...

Combination Treatment of Omega-3 Fatty Acids and Vitamin C Exhibited Promising Therapeutic Effect against Oxidative Impairment of the Liver in Methotrexate-Intoxicated Mice

Conclusions

The findings of this study demonstrated that the use of pretreatment with omega-3 and vitamin C provides significant hepatoprotective capacity against methotrexate-induced liver injury. This was observed by improving the oxidative damage of the liver through the depletion the serum level of MDA and enhancement of total antioxidant capacity, manifested by elevated serum level of SOD and GSH, reducing the level of intracellular liver enzyme ALT (which was the most prominent enzyme responsible for monitoring liver function). Furthermore, the current study illustrated the more synergistic effect of using a pretreatment combination of omega-3 (100 mg/kg) and vitamin C (100 mg/kg) to improve the oxidative tissue damage and liver functions affected by MTX-induced liver injury.

[gomelgo]

mouse models have repeatedly been show to be inaccurate.

[JayPwP in reply to gomelgo]

True

[JayPwP in reply to gomelgo]

Here's an article for perusal

performancelab.com/blogs/mu...

[CaseyInsights]

Interesting Jay, but shouldn’t these two items (Vit C & Omega 3) be on the permanent supplement list of any one with PD?

At least they are on my spouse schedule and I fret when these supplements run out.

I suggest you put it on your permanent list too.

Regards 🌺👍🏾🌺

[JayPwP in reply to CaseyInsights]

I take 1 softgels Super DHA every night but I have not supplemented Vitamin C because it increases iron absorption.

I think I should start now

[CaseyInsights in reply to JayPwP]

Jay, Vitamin C also increases levodopa absorption.

I will err on the side of taking Vitamin C and use ‘iron chelator’ as Curcumin if worried about excessive Iron uptake. 🌺

[JayPwP in reply to CaseyInsights]

Yes, started Meriva Curcumin 3 weeks ago, 1 capsule 500mg alongwith Ginkgo Biloba 1 capsule 120mg first thing in the morning

[gaga1958 in reply to CaseyInsights]

how much vit c? does it cause diarrhea?

[CaseyInsights in reply to gaga1958]

how much vit c?

500mg to 1,000mg should be fine, spread over two doses.

does it cause diarrhea?

Yes there is something called the ‘vitamin C flush is also known as an ascorbate cleanse’. You have to take extremely high amounts to reach this threshold.

[JayPwP in reply to CaseyInsights]

Vitamin C complex would not cause a flush I think