I watch/ listen to/ and skim DOZENS of health videos weekly ... So I just stumbled on this excellent video (except for his negative comment about functional/ integrative medicine prescribing too many tests...).
Best of all, he did a meta analysis of 26 probiotic studies conducted my the NIH/ PubMed.
BOTTOM LINE: Of the gillions of different strains of probiotics the TWO that STOOD OUT as most effective in HEALING a "leaky gut" were:
Blended strains of Bifidobacterium and Lactobacillus.
So I just did my due diligence and RESEARCHED HEAVILY the best brand on Amazon ...
Don't be fooled by the GIGANTIC COST of other brands... They don't have the following:
1. It must be soil-based probiotics.
2. They must contain strains of Bifidobacterium and Lactobacillus.
3. I could not find "MADE IN USA" so the 2nd best marker to look for is to have the label read:
This Swanson product contains wheat. Personally, as a High School Graduate who graduated in the top two thirds of his class, that PD is autoimmune and all autoimmune folks should go gluten free.
You can get Bifidobacterium and Lactobacillus in:
Dr. Matthew Best Probiotic Supplement with Prebiotic. Lactobacillus Rhamnosus, Lactobacillus Gasseri, Plantarum, Casei & Reuteri. Bifidobacterium longum, infantis & lactis. 15 Strains. 50 Billion CFU amazon.com/gp/product/B06XK...
Dr Matthew Best Prebiotics and Probiotics for Women has the 4 strains of probiotics that were used in this study that showed an improvement in UPRDS scores: Clinical and metabolic response to probiotic administration in people with Parkinson's disease: A randomized, double-blind, placebo-controlled trial 2019 core.ac.uk/download/pdf/196...
The 4 strains used in the trial were Lactobacillus acidophilus, Lactobacillus reuteri, Bifidobacterium bifidum, Lactobacillus fermentum.
Maybe take a look at this post also: Probiotics for Parkinson's disease: Current evidence and future directions 2020 healthunlocked.com/cure-par...
As a HS graduate, the jury may still be out on Palm Oil: Balancing functional and health benefits of food products formulated with palm oil as oil sources ncbi.nlm.nih.gov/pmc/articl...
"Conclusion: PO is rich in saturated fatty acids and has a higher stability than other processed oils, which could extend its shelf life. PO is frequently used because it can be fractionated into POl and PS using fractional crystallization, and the fractionated products have distinct fatty acid and TAG profiles. Hence, this study focuses on the impacts of various fractionation conditions on RPO, POl, and PS, as well as their applicability in the food business. Despite having roughly equal amounts of saturated and unsaturated fatty acids, apparently the unsaturation of PO at the sn-2 position does not raise cholesterol levels, resulting in cardioprotective benefits. At the same time, biochemical compounds like tocopherol and tocotrienol could potentially prevent diseases like cancer and diabetes by providing antidiabetic, anti-inflammatory, and antithrombotic capabilities. However, further in vitro research is needed to determine the influence of PO use on consumer health."
Regardless, as Palm Oil is the second to last ingredient listed, I am thinking it is a tiny tiny tiny amount.
all seed oils are very toxic and poison ... stay away from them! (no matter how "tiny" the amount may seem... it tells you the manufacturer is looking for the CHEAPEST way (not the "best most healthful way") to make his product
According to the Dr. Matthew Best product information: "THEY COLONIZE YOUR WHOLE GUT, NOT JUST A PART OF IT
Our BIO-tract controlled release technology makes our probiotics time released, which means your gut is supplied with beneficial flora continuously throughout the day.
Also, as the controllably disintegrated tablets travel inside your gut, they release the good bacteria exactly where you need them: deeply into your small and large intestine, across your whole gut—not only at the beginning of it as in most other formulations which lack the delay release effect."
Dr. Matthew #1 Probiotic supplement contains only human strain probiotics. That means, all 15 strains are natural, safe residents of the human digestive tract. Other probiotic supplements contain Soil Based Organisms (SBO). These tiny dirt dwellers come from the ground and are not naturally found in your body.
Why is this a problem? SBO are not a part of the symbiotic relationship that keeps our immune systems strong. Therefore they are foreign microbes that can become pathogenic especially in people with a compromised immune system. Yet, many probiotic supplements include SBO (i.e Bacilli genera). This is because SBO form spores which have naturally an amazing shelf life as they are resistant to heat, gastric acids, and even antibiotics, giving probiotic sellers a strong marketing proposition! But this spore-forming ability of SBOs is exactly what makes SBO infections so incredibly difficult to treat!
Don’t fall for the marketing pitch. Make sure you buy only human strain probiotics.
Who to trust? Sticking to Dr. Matthew Best for now.
I don't trust ANY of the vitamin manufacturers ... They're crooks!
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But I'm still taking 30 - 40 supplements day hoping that at least '1' is helping and I 'am' feeling MUCH BETTER the last 2-3 weeks! The visible tremors in my hands are ... gone!
Who knows why I'm doing better ... so I just keep doing what I'm doing ....
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As for vitamins, I look for this 'GMP' on the label of any vitamin. And if possible... I always buy... MADE IN THE USA
I used to have a, very rare occasional, tremor in my left hand. It has been gone for at least 3 months. And it used to be when it did not tremor, it still felt like it could. Like it was not solid (if that makes sense), but now the hand feels solid and in control.
also, one of the most important things i learned on that video is that you only need about 5 billion CFUs daily ... and for only 2 - 3 months! ... No other source told me that before ... I'm thinking that probiotics has to be a "permanent" part of my stack ... Not anymore!
READ the "fine print" on the labels and you can see what CROOKS they are!
the "fine print" says... "domestic AND imported ingredients"
so it could contain 1% sourced in the USA and (probably) 99% sourced in China or India where they have practically NON-EXISTENT health inspections/ regulations!
I found the WINNER (after 3 hours!) And I just created a new post, but for your benefit here it is:
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First, I don't believe in "vitamins" but I still take about 30+ supplements daily.
But since I'm "holding back" bad PD symptoms (I'm not officially DX'd) ... with a variety of stuff (vigorous exercise ... today is day $523 of O.M.A.D. ... I've given up just about everything: gluten, dairy, starch, sugar, ultra-processed foods, etc.) ....
What the hell... I just spent at least 3 HOURS on Amazon going through each of their more than 200 probiotic products and only '1' ... meets these 4 criteria:
1. MADE IN THE USA
2. CERTIFIED ORGANIC
3. SOIL-BASED ORGANISMS (on the label it reads: SBO PROBIOTIC = soil-based organisms)
4. Manufactured in a "GMP" facility in the USA.
The price is damn reasonable, too!
Especially because you only need to take '1' (don't take the recommended '2' capsules) to get 25 billion CFUs ... which is still 5X more per day than recommended in video posted below.
Good looking brand. I see they also have Amen Leaky Gut Supplements - Advanced Formula with Bioavailable L Glutamine, Zinc, Turmeric, Licorice Root - Bowel and Stomach Probiotics & Fermented Prebiotics.
Thanks. I noticed he said "Bifidobacterium and Lactobacillus" AND "Soil Based". This tells me the "Bifidobacterium and Lactobacillus" was probably not soil based so I need two probiotics. One with "Bifidobacterium and Lactobacillus" and another that is "Soil Based". I will keep digging. Thanks for raising this topic!
Careful about which bacterial strains and species you supplement with.I read that the average person with Parkinson's has a gut microbiome already in dysbiosis with too much Bifidobacterium and Lactobacillus.
By supplementing these two you might be making things worse.
I can't remember where I originally came across that (an article or research paper about a year ago?), but a quick search for a PD microbiome meta-analysis pulls up this article where a chart shows the relative abundance of various bacteria in PwP vs. controls.
"Our results indicate a higher abundance of the genera Lactobacillus, Akkermansia, Hungatella, and Bifidobacterium in PD gut microbiome. Interestingly, Lactobacillus and Bifidobacterium have been reported to be enriched in the gut of CD patients, and this increase coincided with a decreased abundance of Faecalibacterium sp41, similarly to what we have observed in PD. These taxa are commonly considered to be beneficial bacteria, and whether they are influencing PD or are simply well adapted to thrive in a pro-inflammatory gut environment remains to be elucidated. "
I know I posted his video (which was great) -- but that was BEFORE I learned he's also selling his own line of vitamins.
1. You, I, or a trained monkey could be an Amazon seller of vitamins -- tomorrow!
All you have to do is buy the ingredients from any of tens of thousands of labs worldwide... Then hire a designer to create a nice label.
Bingo! You're in the vitamin selling business!
2. I just posted this below in reply to another member regarding her recommendation of a probiotic website:
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I just checked that website and it FAILED MISERABLY to list the '4 criteria' needed for me (or anyone here) to buy this product:
1. This product is NOT .... "MADE IN THE USA"
2. This probiotic does NOT have ... soil based organisms (per the video recommendation above)
3. This product was not manufactured in a certified "GMP" (Good Manufacturing Process) facility. Very very very few vitamin products go to that safety and health protocol to ensure the BEST product that we have to SWALLOW!
4. This product FAILED to show the label on the bottle so we can determine "source" and "strength" etc of the ingredients.
p.s. pretty website design! but as the famous P.T. Barnum used to say:
"A sucker is born every minute... And two to take him!"
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Nowhere on Dr. Ruscio's website did I see his products were: "MADE IN THE USA."
(that does NOT guarantee legitimacy but it HELPS!)
Please look above at the image of one of his products. It shows a list of this vitamins "qualities/ features."
Can you 'READ' it?
I can't, either.
VERY SUSPICIOUS when a "website" whose purpose is to SELL its products FAILS to fully and clearly disclose those features.
I investigated pro and prebiotics a couple of years ago. My HWP took biokult mind and when nothing changed I looked into and researched many of the ingredients in the pills. Inulin, a fibre produced from chicory roots was in many of them. Many of the other pro biotics as mentioned above were also in Kefir, Kimchi and other foods.
I bought organic powdered inulin, also found a good Kefir and added to my and my husbands diet. At least no more pills! Seems to suit my husband, not so many gut issues like constipation.
Great share, thank you! And apologies for short post - I’ve used MegasporeBiotics for several years as a good Soil Based. One of the doctors I follow then a few years back swapped to Seed, that I haven’t tried nor looked into properly, I just wanted to share if it might be of help to anyone.
2. Nowhere does it say: "GMP" on the label or advertising - "Good Manufacturing Process" (this is a certified industry standard that very, very few vitamin manufacturers offer)
I hear you thank you! From looking at leaky gut for many years it is the soil based product I’ve seen recommended most often by various doctors and supported by user forums. Alas they too over the years have suffered from re-formulations etc. at times. For me it’s still my top one.
I am reading the book: "Fire In The Belly: The Surprising Cause of Most Diseases, States Of Mind and Aging Processes" by Dr Keith Scott-Mumby. Loads of info.
A bit expensive and not available as an e-book but I bought a used one from Alibris.com. I highly recommend it.
Hi PD Warrior, you ARE a warrior with Information! Thank you! I'd like to throw in something else, this company, Biotiquest at biotiquest.com. The founder's husband has PD and she researched all she could and created an exceptional product called Sugar Shift for all of us. She was kind enough to speak with me on the phone after I made an inquiry regarding how this product compered to the Bened product PS 128. I realize you are on a quest for leaky gut, and they do make other probiotics, but wanted to share this product to you and anyone else who may be interested. Thanks for all your incredibly hard work, keep on warrioring!
I just checked that website and it FAILED MISERABLY to list the '4 criteria' needed for me (or anyone here) to buy this product:
1. This product is NOT .... "MADE IN THE USA"
2. This probiotic does NOT have ... soil based organisms (per the video recommendation above)
3. This product was not manufactured in a certified "GMP" (Good Manufacturing Process) facility. Very very very few vitamin products go to that safety and health protocol to ensure the BEST product that we have to SWALLOW!
4. This product FAILED to show the label on the bottle so we can determine "source" and "strength" etc of the ingredients.
p.s. pretty website design! but as the famous P.T. Barnum used to say:
"A sucker is born every minute... And two to take him!"
2. I verify that by contacting the company and asking this:
"What percentage of your ingredients are sourced entirely within the USA?"
If they even reply to that... the answer is almost always: "We have to check and we'll get back to you."
And. They. Never. Do
3. Make sure the bottle is labeled: "GMP" (special designation of manufacturing that very few companies do because it is expensive: "Good Manufacturing Practice"
Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them.
Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked.
Dr. Jonathan Sackner-Bernstein & Dopamine 
DO YOU REALLY HAVE PD?
