Lactiplantibacillus (Lactobacillus) plant... - Cure Parkinson's

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Lactiplantibacillus (Lactobacillus) plantarum PS128

delboy381 profile image
213 Replies

Before I share briefly my experience with PS128 I want to emphasize that this probiotic may not have the same effect on everyone, as we know we are all different.

For four years I have been looking for something to help me with my symptoms. Many of the supplements I use have not given any specific relief until the probiotic Lactiplantibacillus (Lactobacillus) Plantarum PS128, which I felt the other day.

It is not a placebo to immediately dismiss this dilemma because I know this matter very well. My brief experience with the PS128 is 7 days. I know it's too early for some conclusions about its effectiveness, but I couldn't bear to share this news with you. I won’t write much about probiotics. I will put the website so that you can read it for yourself.

benedbiomed.com/

ps128.info/clinical-pd

I know this probiotic has already been mentioned here, but I want to share my experience with it.

I consume the powder 1.5 gr before meals. Active ingredient ps128 30 billion live bacteria. This is a revolutionary psychobiotic.

What relief did I notice with the symptoms:

A clearer head 80%

Tremor 70%

Anxiety 80%

Fatigue 80%

Motor skills 70%

At the end of the post, a quote I read on this site:

Parkinson’s attacks the mind, body, and spirit. Hope treats all three.

- Gordon Adai

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delboy381
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213 Replies
John_morris71 profile image
John_morris71

Glad that it is working for you. I gave it to my mother for 7 weeks and it made no difference.

delboy381 profile image
delboy381 in reply toJohn_morris71

I'm sorry to hear that. Like I said we are all different and the way we developed this unhealthiness. How long has mom had Pd? And what are her main symptoms?

John_morris71 profile image
John_morris71 in reply todelboy381

She has PD since 11 years now. Gave it to her( 60 billion dose/day) almost a year and a half back and did not make a difference. It was from Solace Probiotic, same strain - PS128. (see link below).

She has almost all the typical symptoms associated with PD - constipation - now manageable, balance and gait issues, freezing before walking, anxiety, confusion, fatigue and tremors. But she sleeps well, eats well, can walk for a furlong without stopping if and when she is in the mood - (which is rare).

solaceprobiotic.com/product...

Millbrook profile image
Millbrook in reply toJohn_morris71

John, did she take 60 billion a day? That is the dose in the clinical trial and that is what my husband has been taking since June.

Fed1000 profile image
Fed1000 in reply toMillbrook

Hi Millbrook, which kind of product are you using?

Millbrook profile image
Millbrook in reply toFed1000

Basically I emailed Benedbiomed and asked them for their supplier in Asia.

the website is wellbeingsg.com

Product is called ACTIV health multibiotics containing PS128 +K21

My husband takes 2 sachets according to the clinical trial.

The best thing is to email Benedbiomed, and ask them where you can purchase it. You want the same product. They can name it whatever they like. It is a life changer.

Fed1000 profile image
Fed1000 in reply toMillbrook

Perfect. Thank you very much.

OAFC profile image
OAFC in reply toMillbrook

Is this the one Millbrook?? If so it is selling for $10 now in a 1 for 1 deal.Shipping to the UK is $90

Clear
Millbrook profile image
Millbrook in reply toOAFC

Yes this is the one. Wow S$10 is a steal. It works out to £5 a box excluding shipping. Is the expiry Dec 2021?Everyone who wants to try order this now. It’s a giveaway. It wd be good to order the maximum amount that the £40 shipping cost can allow you.

Thank you for posting the image. I did not know how to do it.

OAFC profile image
OAFC in reply toMillbrook

You’re welcome and yes it’s a bargain and worth a try..Not sure how long delivery takes..Thank you for sharing 🙏

Millbrook profile image
Millbrook in reply toOAFC

You are most welcome and I wish everyone gets the same great results.

OAFC profile image
OAFC in reply toMillbrook

Did it help your husband with Tremors and Dystonia as these are the major symptoms I suffer from predominantly all left sided Very painful Dystonia with my toes, fingers and hand cramping and curling in on themselves and severe tremors in my foot and hand 🙏

Millbrook profile image
Millbrook in reply toOAFC

If you refer to delboy381’s post he said it helped with tremors amongst other things.My husband does not have tremors. He had akinesia-slowness of movt- and balance was a really big thing and he was prone to tripping and falling. So with PS128 his balance was normalised, no more akinesia.

Unlike delboy who cd perceive the difference when taking PS 128, my husband cannot give any feedback. As caregiver I see the improvements.

His driving also improved tremendously, anxiety, sleep all improved as did nocturia

OAFC profile image
OAFC in reply toMillbrook

So happy for you and your husband I hope it helps me with my Tremors and Dystonia as they are really awful at the moment 😞😞One can only try and 😯prey and hope for the best 🙏

OAFC profile image
OAFC in reply toMillbrook

👍🙏

Clear
Buckholt profile image
Buckholt in reply toMillbrook

Best before shown as 18 Dec 2021 so only one month in date once received.

JAS9 profile image
JAS9 in reply toMillbrook

Yes, but I'm in the US and when I go to their website to buy it, there's no shipping option for the US. I suppose it has to do with politics, the pandemic, or the broken supply chain, but that's all beyond my control. Maybe I'll have to row my little boat there!

Millbrook profile image
Millbrook in reply toJAS9

You can message them on what’s app with yr queries. ACTIV health singapore

+65 8862 9039

Ponieboy profile image
Ponieboy in reply toJAS9

Solaris? Is a company that ships US. They aren't cheap though. Thats their big turn off.

Juliegrace profile image
Juliegrace in reply toPonieboy

Solace.

Ponieboy profile image
Ponieboy in reply toJuliegrace

Thank you! Hadn't had my coffee yet....

rebtar profile image
rebtar in reply toOAFC

What do you mean 1 for 1 deal?

OAFC profile image
OAFC in reply torebtar

Buy 1 and get another 1 free

Millbrook profile image
Millbrook in reply toOAFC

Hi OAFC. At S$10 a box there is no one for one deal. When it was S$45, I got the one for one deal.

OAFC profile image
OAFC in reply toMillbrook

Hi I ordered one at $10 and received 2 boxes

Millbrook profile image
Millbrook in reply toOAFC

Hi. When I ordered I got the one for one deal too at $10. So when I ordered 11 boxes I got 22. So lovely. 😃

John_morris71 profile image
John_morris71 in reply toMillbrook

60 Billion per day, not million.

KERRINGTON profile image
KERRINGTON

That's incredible ! Once I research this I will try it. Where can this be purchased ? Thanks

delboy381 profile image
delboy381 in reply toKERRINGTON

Since I live in Europe This powder in sachets is produced in Italy for Bened Biomedical LTD. Company named: Farcoderma I will put a link below.

Someone put here that Solar sells in capsules. Try to find it on Amazon.

The name of the product I use is Second Brain. It looks like this...

farcoderma.com/en/

.
Fed1000 profile image
Fed1000 in reply todelboy381

Hi delboy, how did you by it? From Serbia? Does not seem very simple. The name of the product is Solace or Second Brain? Thanks

delboy381 profile image
delboy381 in reply toFed1000

Yes, through Serbia. I asked a question Millbrook. Which brand to buy and where.

JeanieBeanie profile image
JeanieBeanie in reply todelboy381

I bought Swansons L-Plantera from a Dutch Company. Would be interesting to see if that works for you. Much cheaper. The company is called Body&Fit.

delboy381 profile image
delboy381 in reply toJeanieBeanie

Now for now I will use this brand, time will tell. Thanks for the comment.

Trailing profile image
Trailing in reply toJeanieBeanie

Jeanie, I sure wish the L-Plantarum from Swanson was the same as the PS128 probiotic because I have been having a difficult time finding out where I can purchase it. Evidently it is made somewhere in Asia and not available in the U.S. But there are many strains of L-Plantarum. Here is some info I came across:

Lactobacillus plantarum has been isolated from a variety of hosts such as plants, the human gastrointestinal tract, animals such as poultry and insects, as well as a variety of foods such as meat, fish, vegetables, olives and raw or fermented dairy products (2,4).

Lactobacillus plantarum has been used as a starter culture in the fermentation of many foods such as (5,6):

• Yogurt with live and active cultures

• Raw, unpasteurized sauerkraut

• Pickles brined in water and sea salt

• Raw, aged cheese such as Swiss, provolone, Gouda, Cheddar, Edam, Gruyére, and cottage cheese

• Traditionally baked sourdough bread

• Kefir

• Tempeh, or fermented soybeans

There are a diverse array of lactobacillus plantarum strains the history and evolutionary lineage of which is not clear.

Scientist found the PS128 strain in fermented Chinese Mustard Greens. Evidently this is a common culture condiment in Asia . If anyone knows how we can purchase this probiotic (psychobiotic) in the U.S. please let me know. I would be forever grateful.

JeanieBeanie profile image
JeanieBeanie in reply toTrailing

Hi. My husband has tried it now on two separate occasions with no improvement. In fact it affected him adversely but there could have been other factors. He has had PD 28 years though and had DBS so nothing is straight forward.

Trailing profile image
Trailing in reply toJeanieBeanie

Jeanine if your husband used Swanson's brand it is not the same and therefore cannot have the same affect that has been mentioned here. If it contained PS128 in any significant amount it would specify it on the bottle.

What my reply was trying to explain in that there are a diverse array of lactobacillus plantarum strains and they each do different things in the body. The PS128 strain has been patented and is the strain that has been found to help Parkinson's.

I ordered some today at Solace Probiotics for my husband and will let you know if it works for him. It is expensive but they offer 15% off if you sign up for a subscription which you can change or cancel at any time. They also ship free in the U.S. Hope that helps. Wishing you the best.

JeanieBeanie profile image
JeanieBeanie in reply toTrailing

He has used both the proper trialled powders that is out of stock and the Swansons one.

IEFras11 profile image
IEFras11 in reply toTrailing

it's $99 for shipping to UK so very expensive

KERRINGTON profile image
KERRINGTON in reply todelboy381

I ordered ps 128 from Solace, and it arrived fast. It came packaged with a cold pack. Starting it today.

delboy381 profile image
delboy381 in reply toKERRINGTON

I hope you will have benefits. I wish you all the best. It's all up to us.

KERRINGTON profile image
KERRINGTON in reply todelboy381

👍

Smich profile image
Smich in reply todelboy381

Hi, I can't find anywhere on the link you posted to purchase this, do you have any more info on how to purchase please. 😊

park_bear profile image
park_bear

Search coming up empty. What is the secret to obtaining this?

delboy381 profile image
delboy381 in reply topark_bear

I don't understand the question?

park_bear profile image
park_bear in reply todelboy381

Never mind. Found it. Not cheap. Tempted to give it a try on your recommendation:

solaceprobiotic.com/product...

delboy381 profile image
delboy381 in reply topark_bear

It is a very expensive Solace product.

OAFC profile image
OAFC in reply topark_bear

Found this on Amazon,Not sure if it’s any good but maybe worth a try at the price it is ??

Clear
Fed1000 profile image
Fed1000 in reply toOAFC

This is not delboy's product. This is made in France. I've been using it for a few months with no results.

OAFC profile image
OAFC in reply toFed1000

Yeh I know it’s not the same products as Delboys I just put it on for info and for the price of it…It actually says it’s got the same amount of PS128 in it..Sorry it hasn’t worked for you but like Delboy says everybody’s different and certain things work for one person but not another..Unfortunately that’s the problem with this Godforsaken disease

OAFC profile image
OAFC in reply topark_bear

More info

More info
park_bear profile image
park_bear in reply toOAFC

This product does not seem to be available in the US

OAFC profile image
OAFC in reply topark_bear

See earlier post from “Millbrook” for the one her husband uses with great success and the company she gets it from They’re selling a pack for $10 at the moment due to going out of date soon..I’ve just ordered 2 boxes and they ship all over the world..I’m in the UK

glenandgerry profile image
glenandgerry in reply toOAFC

Any idea how much you'll have to pay for import duty and tax into the UK?

OAFC profile image
OAFC in reply toglenandgerry

The total cost for everything is £54

OAFC profile image
OAFC in reply topark_bear

This is the one “Millbrook” gives to her husband

Clear
OAFC profile image
OAFC in reply topark_bear

👍

Clear
OAFC profile image
OAFC in reply topark_bear

wellbeingsg.com/product/mul... This is the Link 👍

park_bear profile image
park_bear in reply toOAFC

Yes that is a possibility. They do want $50 US to ship from Singapore.

OAFC profile image
OAFC in reply topark_bear

Yeh it’s costing me £40 to get it delivered to the UK…If it helps dramatically though that will be a small price to pay 🙏🙏

Buckholt profile image
Buckholt in reply topark_bear

Best before shown as 18 Dec 2021 so only one month in date once received.

FawnLily profile image
FawnLily in reply topark_bear

$50? They want $70 for shipping to me and I am on west coast 🤔

park_bear profile image
park_bear in reply toFawnLily

That is in Singaporean dollars. They are worth US$.75, which comes to a bit more than $50 US.

Turnipbarrow profile image
Turnipbarrow in reply topark_bear

Was this for one box? I put in two boxes and shipping is $103 US dollars to arizona.

JeanieBeanie profile image
JeanieBeanie in reply toOAFC

Thank you. Just ordered 4 boxes and cost £62 I think with delivery to uk. Will try this and see how it compares to Swansons.

OAFC profile image
OAFC in reply toJeanieBeanie

Good Luck 🙏

Turnipbarrow profile image
Turnipbarrow in reply topark_bear

Solace is very expensive when compared to wellbeingsg.com. I have been wanting to buy it but couldn’t get past the price on solace. I just bought 6 months worth ( 12 boxes) from the wellbeingsg.com for about the same price as 3 boxes from solace. I’m hoping it is worth it!

Millbrook profile image
Millbrook in reply toTurnipbarrow

Fingers crossed🙏🏻

I ordered for 1 year and put them in the freezer

in reply todelboy381

can you post where from did you order?

in reply to

I found it in Serbia - it costs 25EUR , 30 packs.

beopanax.com/sr/proizvod/se...

delboy381 profile image
delboy381 in reply to

That's it! They import from Italy. The factory for production in Italy is called Farcoderma.

Robb48 profile image
Robb48 in reply todelboy381

Curious thing re the French product - looking at the website for Bened, the company developing PS128, they have a world map showing location of manufacturing facilities, and also "Bened product markets" - France is not included in either. Hmm. Also I found an article from a couple of years ago with the headline "EU firm Beopanax selected as exclusive psychobiotic product distributor". But maybe this is out of date?!

So, struggling to find out how to get it to the UK now, without going with the French "Neurobiotique". I think I'll send a quick message to Bened asking on both issues.

glenandgerry profile image
glenandgerry in reply toRobb48

Same here, I'm in the UK and also struggling to find the best/cheapest way of getting 'Second Brain'

Robb48 profile image
Robb48 in reply toglenandgerry

I left a message for them on their site re both questions above, and the advisability of international postage given requirement for refrigeration - will post here their response when they get back to me.

glenandgerry profile image
glenandgerry in reply toRobb48

Awesome, thank you so much

Robb48 profile image
Robb48 in reply toglenandgerry

Reply copied from Bened:

"..we provided PS128 to Synergia for their product in the past. Currently, we are supplying the strain in the EU to Neuraxpharm (for product Neuraxbiotic Spectrum, sold in Spain, Portugal, Germany, Poland, Czech Republic, Slovakia, Austria, Hungary, Italy) and Beopanax (for product Second Brain, sold in Serbia, Kosovo, Bosnia, Montenegro, Macedonia, Croatia, Slovenia, and Albania).

Regarding shipping and efficacy, you're right that lack of temperature control can negatively affect a probiotic's potency. The PS128 strain should always be refrigerated when possible. We know that is not always practical during shipping, so each of the products listed above include enough overage (extra PS128 above the amount guaranteed for each dose) for at least that amount left at their expiration date - even considering some shipping time at room temperature. Especially now that outside temperatures are cooler, the CFU count should not be decreased by much before the order reaches you.

Unfortunately, there is not currently a distributor selling a product with PS128 in the UK. In the meantime, I can recommend a few different PS128-containing products:"

- They go on to recommend Solace (US) and Activhealth (Singapore) in addition to the above. I've now bought from the latter, with the special offer, close to use by date sachets. Also asking Bened to check that freezing is unwise (probably) and what the normal shelf life is, so I can see how quickly it degrades.

Robb48 profile image
Robb48 in reply toRobb48

Another reply from Bened:"Under normal refrigeration, PS128's shelf life is at least 2 years. Freezing the product is just fine. Feel free to store them that way if you'd like to keep them even longer."

Nice! So the almost expired products many here are buying can be chucked in the freezer to last for longer.

Love the customer service from these guys too.

Millbrook profile image
Millbrook in reply toRobb48

Thanks! I just ordered a whole years worth and put them in the freezer. At the clearance price it’s a steal.

delboy381 profile image
delboy381 in reply toRobb48

It’s not outdated because the date is good on the boxes. You need to send an email with an inquiry. At least it doesn't cost anything.

glenandgerry profile image
glenandgerry in reply todelboy381

Did you email them? I thought we had to place the order online, no?

JeanieBeanie profile image
JeanieBeanie in reply toRobb48

Check OAFC's link above. Just ordered some.

Robb48 profile image
Robb48 in reply toJeanieBeanie

Looks interesting, and the price is good (had to look hard to see it is 30 sachets!), unfortunately they dont give a breakdown for the number of PS128 cells vs the two other cultures they have in the sachets. Although PS128 is listed first on the ingredients, so I guess the minimum is 1/3rd. Give the low price I guess just take more :).

Buckholt profile image
Buckholt in reply toRobb48

This is widely available in mainland Europe, but waiting to find out if there’s a UK distributor.As I understand it is, Neuraxpharm are the European Licence holder

.
Robb48 profile image
Robb48 in reply toJeanieBeanie

Damn, didnt see they have two products, including MIND rather than ACTIV. The former is only PS128, I just ordered the latter, oops.

Millbrook profile image
Millbrook in reply toRobb48

ACTIVE is the one recommended for PD

JayPwP profile image
JayPwP in reply toMillbrook

It seems the only recommendation for PD is PS128

Millbrook profile image
Millbrook in reply toJayPwP

My husband is taking the ACTIVE formulation which has PS 128 (30 billion) and K21.

JayPwP profile image
JayPwP in reply toMillbrook

Millbrook,

The ACTIV contains PS128 + K21, both combined totalling 30 billion CFU.

MIND contains only PS128 totalling 30 billion CFU.

The research does not emphasize K21 strain, only talks about PS128.

Maybe the combination is better, but nothing is documented in favour of the combination.

Despe profile image
Despe in reply toJayPwP

I was wondering if K21 is same as Bio-Kult's PXN 21.

JayPwP profile image
JayPwP in reply toDespe

Maybe. Here's the response from Bened:Hello Jay,

I'm glad to receive your email. We are currently working with a distributor in India, and the product is nearing the registration stage. However, that process is likely to take several months before the product is available for purchase from India. I will be sure to let you know when that happens.

In the meantime, Activhealth in Singapore (Multibiotics | Activhealth | Healthy Mind, Healthy Body) and Solace in the US (SOLACE – Solace Probiotic) may be able to ship internationally. Please contact them directly for specific product information or to purchase.

Robb48 profile image
Robb48 in reply toMillbrook

Curious why you think the Active is recommended for PD, did you ask one of the companies for advice? I've sent a quick message to see if my order can be amended to some of both, so I can try each on my Mum when they arrive (has MSA)

Millbrook profile image
Millbrook in reply toRobb48

Yes I spoke to them and when I mentioned PD they said ACTIVE was the one I should order. I had initially ordered MIND but changed to ACTIVE after speaking to them.

So my husband has been on it since june. It has been about 4.5 months

I did speak to them about K21 and what it was supposed to do. She mentioned reducing inflammation and lipids. I was too happy that I could get the product, made in Taiwan right here. And since she said her PD clients took ACTIVE I ordered it. They also have other probiotics for autism , depression etc

Robb48 profile image
Robb48 in reply toMillbrook

Oh interesting, thanks for the reply!

JayPwP profile image
JayPwP in reply toMillbrook

The ActiveHealth website recommends the combination PS128 + K21 for Neurological disorders

activhealth.com.sg/multibio...

glenandgerry profile image
glenandgerry in reply to

I emailed them - they replied saying they are unable to supply the UK

Millbrook profile image
Millbrook in reply topark_bear

PB look at OAFC ‘s post on the PS 128 that my husband is taking. It’s on special about £5 a box. You have to pay for shipping but you can order the max amount that yr shipping costs allows. The website is wellbeingsg.com

Despe profile image
Despe in reply toMillbrook

Millbrook,

Last week I received my second order of Solace (3 boxes) which is very expensive. Thanks to you and OAFC, I will start ordering the one you have been using on your husband. I bookmarked the site. Thanks!

Millbrook profile image
Millbrook in reply toDespe

Hi Tina,

I think that the product can still be consumed one or two months after expiry date. It’s essentially powder form and as long as it is stored properly should be fine.

That’s just my opinion.

It’s amazing the delboy381 only takes 1 sachet and has got such good results. The clinical trial used 2 sachets at bedtime.

Wishing you the same miraculous results .

Buckholt profile image
Buckholt in reply toMillbrook

Best before shown as 18 Dec 2021 so only one month in date once received.

chartist profile image
chartist

delboy,

Forum member Millbrook reported very good results in her husband using PS-128 over a relatively short period of time also!

Art

delboy381 profile image
delboy381 in reply tochartist

I glad to hear that. I don’t want to claim anything about this probiotic, but so far for the first time I feel like something from the supplements is helping me. It boosted my self-confidence. My opinion is that the end of this unhealthiness is getting closer. One part of Michael's interview I recently read:

With the Foundation, which has raised over $1 billion to date for Parkinson's research, "we are loading up all the cannons we can and pointing them at the target," Fox told PEOPLE earlier this week. "One of them will fire and it will happen. The disease is a problem that will be there until you solve it. But we're hopeful."

Millbrook profile image
Millbrook

Hi Delboy,

I wrote a post on PS 128 in June 2021. Within 2 weeks there was 180 degree turnaround affecting balance, stiffness, slowness, driving. Everything was normalised. It was a miracle. My husband takes 2 sachets -60 billion- at bedtime.

He took the probiotic at the same time as doing the coronet duo 2x a day so now we are committed to both.

I am so happy for you that PS 128 accomplished as much as it did for us.

My husband has been taking it since June and continues to take it daily and the improvements have been sustained. You can click on my icon and read my post on PS 128. Like you I was so excited and happy about the improvements I could not wait to share with my friends here on HU so that they too could experience the same benefits.

delboy381 profile image
delboy381 in reply toMillbrook

Hi Millbrook.

I'm glad to hear that. Believe me, I felt the effect after the second day. I use one sachet and take it before lunch, mixing it with water for half an hour. Like I told Art, it boosted my confidence. Time will tell. I wish you all the best. Oh, can you put where you buy ps128?

Millbrook profile image
Millbrook in reply todelboy381

I live in Asia and got the contact from Benemed itself. They Mail mainly to NZ, Australia n Asia.

The website is wellbeingsg.com

The brand is ACTIV health multibiotics containing PS 128 and K21.

This contact was given to me by Benedbiomed.

They had a one for one promotion to clear stocks that were expiring Dec 2021. Price is S$45 for box of 30 so you need 2 boxes for a month.

I am very glad that you have experienced the same great results.

Thank you for validating my post.

delboy381 profile image
delboy381 in reply toMillbrook

I suggest members who live in the USA who are interested in this product contact directly at benedbiomed.com/ to see how to order for the USA.

rebtar profile image
rebtar in reply todelboy381

I just ordered from the Singapore website mentioned above. No problem. Including shipping costs $141 to US for four boxes.

delboy381 profile image
delboy381 in reply torebtar

Good. I hope you will have benefits.

rebtar profile image
rebtar in reply todelboy381

I hope shipping from Singapore is done in a way that the product isn't damaged in shipment. Many but not all probiotics are very sensitive to temperature.

delboy381 profile image
delboy381 in reply torebtar

I really don’t know, I have no experience with that kind of order and shipping. It's going to be alright.

Millbrook profile image
Millbrook in reply torebtar

According to the supplier the product is not affected by temperature unless it is very hot but best to store it in cool and dry place once you receive it.

WinnieThePoo profile image
WinnieThePoo in reply toMillbrook

That seems surprising. All lactobacillus are sensitive to temperature and deteriorate quite quickly. You can probably test viability by making a yoghurt from a sachet. Don't worry what it tastes like, as long as it ferments into yoghurt

Millbrook profile image
Millbrook in reply toWinnieThePoo

Personally I store mine in the fridge though I was told it was not necessary as long as it was a cool place. Heat is more of a problem here. I will try making yoghurt with it and let you know.

Millbrook profile image
Millbrook in reply toMillbrook

Yay!!! The yoghurt formed was beautiful and tasty.

If only I could know how many billion in it

Millbrook profile image
Millbrook in reply toWinnieThePoo

Hi WTP,

I made a yoghurt with one sachet of PS128+K21. After some of you mentioned temperature concerns ( nowhere is hotter than being on the equator) I did it to placate my own fears that all the live probiotic were dead.

So happy to report yoghurt taste really nice and pleasant- not sour

and very palatable .

Bythejerseyborder profile image
Bythejerseyborder in reply toMillbrook

How long did your yogurt incubate for? I did 36 hours.

Millbrook profile image
Millbrook in reply toBythejerseyborder

I stopped making the yoghurt cos my husband preferred to take the sachets- 2 before bedtime.

It’s an amazing product doing what it does for him. 🙌

I am so thankful.

lionessroar profile image
lionessroar in reply torebtar

Have you actually received your order? I placed an order from the Singapore site 12 days ago and just received this message "... the parcel has just been rejected by the US customs due to some unforeseen circumstances." 😔

rebtar profile image
rebtar in reply tolionessroar

I received my first order. I placed a second order and have not received it or a message like yours. I messaged them through their website, waiting for a reply.

FotoWorkz profile image
FotoWorkz in reply tolionessroar

I placed an order over a month ago & it was also refused at customs, then returned to Singapore. Because of these refusals they are no longer shipping to the US.

AlBravo profile image
AlBravo in reply toFotoWorkz

Hi, were you able to get it shipped to USA? I ordered the Activhealth – Multibiotics thru wellbeingsg.com from Singapore about 3 weeks back. It's currently showing that the shipping package has arrived in US but held at the Customs.

Does anyone has an idea how to get it released from US Customs?

Thank you for your help!

FotoWorkz profile image
FotoWorkz in reply toAlBravo

Hello-Unfortunately, US Customs returned it back to WellBeing in Singapore. I was given a prompt full refund and WellBeing said they were going to change their site to not allow US buyers to purchase it, because of the many orders being returned by customs.

Sydney75 profile image
Sydney75 in reply toFotoWorkz

bought it from US supplier solace probiotic.

AlBravo profile image
AlBravo in reply toSydney75

Ok, got you. I thought Solace Probiotic has a different strain than what was actually used in the research study.

How has been your experience using the Solace Probiotic. Did you find any benefit with the PD symptoms? Thanks!

AlBravo profile image
AlBravo in reply toFotoWorkz

Oh ok, sorry to hear that. Looks like it's going to be the same experience for me as well and will prolly be returned by the US customs. Fingers crossed though!

Redginger profile image
Redginger in reply toMillbrook

Why should we get the one with K21 added? I dont see that it says anything about buy one get one.

Millbrook profile image
Millbrook in reply toRedginger

Hi Redginger,You can buy which ever one appeals to you. There is no compulsion here.

Redginger profile image
Redginger in reply toMillbrook

Yes, I realize. I just wondered why that one was preferred. I read more this morning and did choose that one. After such connection trouble last night I tried again this morning and finally was able to complete order. There was no 1 for 1 that I could find but I was able to get a good deal, I thought. Just now hoping for survival in the shipment. Thank you for your contributions to this group, Millbrook.

Rccoble profile image
Rccoble in reply toMillbrook

Hi! Was wondering if your husband is still using this and if it continues to have positive effects? I haven't seen any recent posts from you and am considering ordering.

Millbrook profile image
Millbrook in reply toRccoble

Hi. Sorry just saw your message. Yes, he is still taking 2 sachets before bedtime every night. It is something that he will continue taking for life. It seems that 70% of dopamine is produced in the gut . This probiotic is God sent.

Millbrook profile image
Millbrook in reply todelboy381

Wow. It worked for you on only 1 sachet? Awesome🙌

Buckholt profile image
Buckholt

I notice that with the French sourced version, they suggest storage at between 4 and 7 degrees, preferably in the refrigerator. Seems precise and I wonder if this applies to other versions? Would international shipping affect the efficacy, as storage temperature would be out of control?

synergiashop.com/en/neurobi...

Fed1000 profile image
Fed1000 in reply toBuckholt

I used the French version for a while. They use special packaging for sending. it shouldn't deteriorate.

Farooqji profile image
Farooqji in reply toBuckholt

Yes definitely the conditions during shipping Will affect the efficiency. I had contacted the main manufacturer a few months back and his reply was as under"I’m glad to receive your email. Currently, we do not have a distributor that covers your country. PS128 is a delicate probiotic that is best kept refrigerated and shipped via cold chain, and logistically, that is quite difficult in your country. Our Singapore distributor, Multibiotics | Activhealth | Healthy Mind, Healthy Body, may be an option. Please contact them directly and see.

If there is anything else I can help with, please let me know.

Only the best,

Sam Noble

Int'l Dept. Product Manager, Bened Biomedical

mob: +886-9-7831-4917 | tel: +886-2-2511-1122

benedbiomed.com"

Millbrook profile image
Millbrook in reply toFarooqji

The website for ACTIV health is wellbeingsg.com

Robert3 profile image
Robert3

Sorry, I have a different experience. I take PS128 already 2 months - 60 billions daily. There are no improvement of none of my symptoms. My PD was diagnosed two years ago. This is NeuraBiotic Spectrum produced by Bened Biomedical Co.Ltd in Italy.

delboy381 profile image
delboy381 in reply toRobert3

Hi Robert.

I have emphasized that we are not all the same and that it may not have the same effect in another, similar to B1. It is not my intention to give false hope to anyone.

We are in a position to look for what will make our life easier and better. All the best.

Millbrook profile image
Millbrook in reply toRobert3

Sorry to hear that Robert. Perhaps you may want to try the coronet Duo that other members are using as well. My husband used coronet duo and PS128 simultaneously. I was inclined to think that the change was due to PS 128 because red light takes time to be effective.

We are not promoting any product and have nothing to gain from it other than helping others get better.

In the clinical trial that ran for 12 weeks 70% of participants experienced improvements and 20 % of the 70% experienced great improvements.

It is worth trying for everyone. It does not cost an arm and a leg at the clearance price and it could very well change your life.

It was life changing for me. Previously I could not leave my husband alone for fear of falls. Now his balance is normal and he can function independently. He is more alert and functions normally in everything. The slowness is gone. It’s a miracle 😭

ccr69 profile image
ccr69

Where do you get the probiotic from, is it reliable on delivery?

Romulus13 profile image
Romulus13

It could be beneficial.I don't have PD I have Parkinsonisms and I've been taking it for 6 weeks with a lot of other supplements. Had some minor tremor improvements hard to say because of what. But I have stopped now because recently I am experiencing some dizziness (don't know the reason yet) and I'm on regular probiotics.

RBan profile image
RBan

My probiotics say it contains lactobacillus plantarum (LP-115). Can anyone explain the difference? Thx.

Millbrook profile image
Millbrook in reply toRBan

Plantarum has different strains. This is specifically PS 128 in the plantarum family. So all the other strains are different.

RBan profile image
RBan in reply toMillbrook

So this means the other strains aren’t effective?

Millbrook profile image
Millbrook in reply toRBan

Essentially the clinical trials used PS128 to get those results. Taking other strains have no proven track

Also the dose is 60 billion which is 2 sachets daily - 2 boxes a month

However delboy381 only took 1 a day to get results. But Faridaro who took 1 a day had no results

RBan profile image
RBan in reply toMillbrook

Thx Millbrook!

Millbrook profile image
Millbrook in reply toRBan

If you want to try PS 128 now would be a good time as they are clearing stocks that are due to expire Dec 2021. This is the one that my husband is taking. It works out to about £5 for a box of 30 sachets excluding shipping. Best to order maximum amount that the standard shipping allows.

The website is wellbeingsg.com

You would need 2 boxes a month as the clinical trial used 60 billion at bedtime for 12 weeks.

Wishing you all the best

chartist profile image
chartist

I know these were likely posted in previous PS128 threads, but it is relevant and worth posting again :

ncbi.nlm.nih.gov/labs/pmc/a...

ncbi.nlm.nih.gov/labs/pmc/a...

ncbi.nlm.nih.gov/labs/pmc/a...

pubmed.ncbi.nlm.nih.gov/343...

ncbi.nlm.nih.gov/labs/pmc/a...

ncbi.nlm.nih.gov/labs/pmc/a...

ncbi.nlm.nih.gov/labs/pmc/a...

sciencedirect.com/science/a...

And the US does not make this product because.....? Clearly there is a market for it!

Art

Millbrook profile image
Millbrook in reply tochartist

Thank you Art- our trusty resource library

Sydney75 profile image
Sydney75 in reply tochartist

Thanks!

Discogs_discogs profile image
Discogs_discogs

I already take Lactiplantibacillus (Lactobacillus) plantarum as a probiotic supplement by SWANSON:

swansonvitamins.com/swanson...

For all I know, the very inexpensive Swanson L. Plantarum supplement might be partially comprised of the PS 128 strain. In fact, it might even be entirely comprised of PS 128. The label simply does not specify which substrain of L. Plantarum is in the bottle.

WinnieThePoo profile image
WinnieThePoo in reply toDiscogs_discogs

And dog food made from "meat & animal derivatives" might be made from lean fillet steak.

Probably it isn't

If it was made from lean fillet steak pet food labelling laws permit the manufacturer to say so

And guess what?

Bolt_Upright profile image
Bolt_Upright

This is not an endorsement but I was just clued in to this one: Thryve Inside Mood Enhance Probiotic

amazon.com/dp/B089MBWQRS/re...

Ingredients

"Probiotic Strains : Proprietary Probiotic Blend 500mg Lactobacillus plantarum PS128™ +5 billion, 5 billion Lactobacillus paracasei PS23™, Mix7 (St. thermophilus Z57, Lb. delbrueckii ssp. Bulgaricus LB2, Lb. acidophilus LA1, Lb. plantarum 14D, Lb. paracasei 101/37, Bf. breve Bbr8, Bf. breve BL10, Bf. animalis ssp. lactis Bi1) "

Millbrook profile image
Millbrook in reply toBolt_Upright

Hi Bolt. The PS 128 is30 billion in one sachet

Bolt_Upright profile image
Bolt_Upright in reply toMillbrook

Yes. This one you get 5 billion but it only costs $30 for 30 capsules.

JAS9 profile image
JAS9 in reply toBolt_Upright

Yes, I saw this too. So, you'd take 12 capsules a day?

Cost is about $12/day or about $360/mo!

What if I bought one month's supply of Solace then used some of that to ferment my own PS128? (Instructions on how to make your own probiotics are easily found on the internet.) According to Solace's website, they use fermented mustard greens. The only problem is dosing, but is that really a problem? After all, we're talking about swallowing fermented food (that is quite safe; fermented foods have been around a long time and are generally health-promoting). These fermented foods already have, by definition, bacteria that caused the fermentation. If I'm careful and introduce PS128 into the process I should be able to consume at least a small amount of the fermented mustard greens without any problems. If I get too much of it, my gut might make even more dopamine than somebody getting "just" 60bln CFUs. That wouldn't be terrible. Am I wrong?

WinnieThePoo profile image
WinnieThePoo

It will be interesting to see a longer term report. "Next day" improvements are usually placebo effect, but not always.

"The trials" are far from conclusive (human PD trials - not immodium induced mouse constipation trials)

NCT04722211 - a proper trial, listed Jan 21, 120 participant placebo controlled , still recruiting, due to report end next year

PMC8277995 - open label, 25 participant 12 week duration 2021. Interesting, but needs a trial like NCT04722211 to corroborate

NCT04389762 open label 120 participant 12 week duration COMPLETED June 2020 - no results posted. No results posted 15 months later usually = "didn't work"

NCT03566589 2018 trial - no results posted

The trials are all of PS128 - not the cocktail with K21. So 60 billion cfu of a reputable sourced PS128 - like Synergia Neurobiotique, if kept cool in transit and storage, should be equivalent to the trial.

Forum feedback on this thread seems to be pretty evenly split between "didn't work for me" and "great results"

As I said at the start, it will be interesting to see the results 6 months out

JayPwP profile image
JayPwP

Cant find any availability in India. Have written to wellbeingsg and bened as well. Let's see

Millbrook profile image
Millbrook in reply toJayPwP

You can order it on wellbeingsg.com or WhatsApp them on +65 88629039 with your questions

Product is made in Taiwan

JayPwP profile image
JayPwP in reply toMillbrook

Thanks

JayPwP profile image
JayPwP in reply toMillbrook

And they say they don't deliver to India. Also they are out of stock due to the December expiry.

Buckholt profile image
Buckholt

I understand that a licence has been granted in Europe to Neuraxpharm, to distribute PS128 . The Neurorax Biotic Spectrum product looks widely available in continental Europe, but not UK. I have emailed the company to see if there is a UK supplier.

.
Sapeye2020 profile image
Sapeye2020

I used to make wines with a group of friends and we started by using prepacked yeast variety's . being slow learners it took about 15 years to smarten up and use a yeast that mother nature developed rather than just any old 'YEAST' and we started to have superbly flavour and body, etc.

Think of that statement about bunch of grapes down in the far corner of the Vinyard that is harvested yearly and has superb flavour and body. far better than the rest of the variety adjacent.

Now, what is one of the factors that is missing from this discussion of a very finely (?rare) refined yeast? (PS218)

If you give up here is the answer: There has been NO discussion of the foods or style of meals/foods ie Vegan, Meat-a-terian, etc.

The inclusion of that information would help others reading "It worked for me" if there is a reasonable chance of success.

Just saying....

Sydney75 profile image
Sydney75

What's best time of day to try prebiotic? Don't want stomach upset, with or without food?

delboy381 profile image
delboy381 in reply toSydney75

Hi, I use one sachet half an hour before lunch. Honestly I have stomach pain sometimes and I guess that’s normal because there’s a little war going on in the gut flora. A member Millbrook her husband used in the way described in the study, at bed time. I said time will tell how effective this probiotic is.

Millbrook profile image
Millbrook

I just made a batch of yoghurt from 1 sachet of PS128 +K21. So they are alive! Maybe you may want to try. Only thing is you will not know how many billion in it and how much to consume to get 60 billion dose

Rhyothemis profile image
Rhyothemis

I purchased some from Solace in the summer. The first shipment arrived hot (literally hot to touch) and I asked for a replacement. The next batch was a bit warm, but not as bad.

Customer Service said -

"In regards to your concern about Solace being exposed to heat, there was a study conducted examining this very question. When tested at 77 degrees Fahrenheit (5 degrees above room temperature) for 30 days, 75% of the probiotics survived. When tested at 99 degrees Fahrenheit, for 15 days 50% of the probiotics survived."

I tried one and got a definite effect a few hours later - a flare up of lower back and urogenital pain. Same as what happens if I take Lion's Mane.

So it isn't for me, but FWIW my experience was that even after getting hot it did appear to be active and it did something. I can't speak to PD symptoms since I don't have PD.

BDNF is implicated in chronic pain: nature.com/articles/s41598-...

Rhyothemis profile image
Rhyothemis in reply toRhyothemis

I should add that I eat tons and tons of fiber, so plenty for little beasties to feed on and do their thing.

JayPwP profile image
JayPwP

Just in case one wonders where to buy:

The strain was isolated and patented by Professor Tsai Ying-Chieh[13] (National Yang-Ming University) and sold as a supplement ingredient by the company he founded, Bened Biomedical.[14]

In Europe, CNS pharmaceutical company Neuraxpharm, markets a product for autism containing PS128.[15] Synergia sells in the probiotic in France.

Solace and Thryve are brands containing PS128 in North America.

In Malaysia, Nuvanta sells a PS128 product.[16]

In 2020, Blackmores, an Australian health supplements company, announced plans to develop a PS128 product for the Australia/New Zealand market.[17]

OAFC profile image
OAFC

How many sachets is the 1.5 grams and did you take that before every meal?

Millbrook profile image
Millbrook in reply toOAFC

Each sachet has 30 billion. According to the clinical trial 60 billion -2 sachets- is consumed at bedtime.

rebtar profile image
rebtar in reply toMillbrook

In water or dry?

Despe profile image
Despe in reply torebtar

I received my order yesterday. Instructions are on the outside of the box.

Millbrook profile image
Millbrook in reply torebtar

Either is fine but my husband just pours sachet into his mouth and eats it like that.

enjoy2013 profile image
enjoy2013

I wondered if anybody taking PS128 here for PD could give an update?

Millbrook profile image
Millbrook in reply toenjoy2013

My husband is still taking 2 sachets a day at bedtime and will continue to do so. The improvements remain. He does not have issues with slowness, driving, balance he previously had.

enjoy2013 profile image
enjoy2013 in reply toMillbrook

Thank you, that's really great news. Could he decrease the dosage of his levodopa treatment?

Millbrook profile image
Millbrook in reply toenjoy2013

He is not on any medication for PD other than vitamin B1, PS128 , coronet duo and ubiquinol.

KERRINGTON profile image
KERRINGTON in reply toMillbrook

How long has he had PD ?

Millbrook profile image
Millbrook in reply toKERRINGTON

He has not been diagnosed. He lost his sense of smell about 8-10 years ago together with gut problems , active dreams which were even earlier. He also had nocturia waking 6-8 times a night. Three years ago, started having frozen facial muscles, choking on saliva, Poor lane discipline when driving and slowness. Started vitamin B1 and it improved. Balance was worse this year and we started coronet duo and PS 128 and it has been very good especially his balance and driving. Everything is normal.A visit to neurologist last year for vertigo confirmed that he was slower on one side. His advice was PD has slow progression and not to worry about it and there are meds to help. He said he could not definitively say he had PD or he did not have PD.

Essentially saying we will deal with it as it goes.

enjoy2013 profile image
enjoy2013 in reply toMillbrook

I am impressed with the results you got, thanks for sharing

KERRINGTON profile image
KERRINGTON in reply toenjoy2013

I've been on it a month and have not noticed any improvement. I'll try for 5 more months.

Millbrook profile image
Millbrook in reply toKERRINGTON

Hi.

Could you link your other comment that after 3 months you got some results

Following_closely profile image
Following_closely in reply toMillbrook

Time for another PS128 update? I'm not sure why this showed up in my feed because I can't see any recent entries. However, it sounds like a few people may have began taking this about 6 months ago. Does anyone have anything to report, good or bad?

Thanks!

Since this stuff is so expensive in the USA, has anyone tried to make yogurt with it? Dr William Davis's book Super Gut has instructions. With yogurt making you would only need 1 box for $99 and then use a couple of Tbs of made yogurt, to make a new batch.

faridaro profile image
faridaro in reply toBythejerseyborder

I believe someone on this forum had the same idea but then there was a question - how do you get a specific dose of this probiotic if it's in yogurt?

Edit: just realized that Millbrook (see thread below) made yogurt, so may be you get some details about that experiment.

Bythejerseyborder profile image
Bythejerseyborder in reply tofaridaro

Dr Davis recommends a 1/2 cup per day of homemade yogurt for other probiotic made yogurts. Sometimes 1 cup

JackAubrey profile image
JackAubrey

Hi All, as you know by now, Bened LIfe bought Solace and has a US patent on lactobacillus plantarum ps128 which they call Neuralli. They are now charging $164 a bottle or $115.50 a bottle if you buy three months worth.

If you're looking to save money and you look elsewhere out of the US, either the product is out of stock or shipping costs make it even more expensive than Neuralli. I have emails out to a pharmacy in Spain where I can't even do a Euros to $ conversion because of the crazy way they've stated the price, but this aside, I can't find any less expensive source. As if we didn't all deal with high enough costs already between supplements and drugs, right?

Does anyone know of a reasonably priced source for lactobacillus plantarum ps128 where shipping to the US doesn't break the bank...or does such a source not exist and we're stuck with the cost of Neuralli here in the US?

TL500 profile image
TL500 in reply toJackAubrey

I find the same as you. I wanted to buy from Neuralli but not only it's too expensive, the shipping cost to Australia is $99usd or something.

TL500 profile image
TL500

Hi, do you or does anyone know if I can take this probiotic PS128 while taking Azilect or Rasagiline? Thanks

JackAubrey profile image
JackAubrey in reply toTL500

This pilot study says you can take it with any PD drugs. The Add-On Effect of Lactobacillus plantarum PS128 in Patients With Parkinson's Disease: A Pilot Study frontiersin.org/articles/10...

TL500 profile image
TL500 in reply toJackAubrey

Thanks Jack

JackAubrey profile image
JackAubrey

Ok, so the person I care for who has PD bought a 3 mo. supply of Neuralli because they want to emulate the pilot study on Lactobacillus plantarum PS128 which went for 3mo. So I'll be back on this thread sometime after the first of the year to let you all know our results.

JayPwP profile image
JayPwP

Quick question:

Any recommendations on what to eat in order for the PS128 in the gut to generate dopamine?

JayPwP profile image
JayPwP in reply toJayPwP

No takers?

delboy381 profile image
delboy381 in reply toJayPwP

Hi, honestly, I take a sachet after breakfast and I don't have a strict diet. I took a break from PS 128, now I'm using it again.

JayPwP profile image
JayPwP in reply todelboy381

Thanks. The label says take on empty stomach or 1 hour after a meal

delboy381 profile image
delboy381 in reply toJayPwP

I don't take the sachet right after breakfast maybe 30 or 45 min later.

WinnieThePoo profile image
WinnieThePoo in reply toJayPwP

Why would you want PS128 to generate dopamine in the gut?

JayPwP profile image
JayPwP in reply toWinnieThePoo

Because some believe Dopamine is generated in the gut and transported to the brain via vagus

WinnieThePoo profile image
WinnieThePoo in reply toJayPwP

I think the scientific orthodoxy is that dopamine made in the gut can't cross the blood brain barrier, and that would include can't dodge it via the vagus nerve, and that it is a cause of side-effects . Drugs like Carbidopa are used to stop dopamine being metabolised outside the brain.

Is there any good evidence for this belief of some people?

JayPwP profile image
JayPwP in reply toWinnieThePoo

There were some comments on this forum itself. Will try to search.

JayPwP profile image
JayPwP in reply toWinnieThePoo

healthunlocked.com/cure-par...

WinnieThePoo profile image
WinnieThePoo in reply toJayPwP

Hmm. Thanks for the link, but I don't think that amounts to a great deal

JackAubrey profile image
JackAubrey

My wife recently finished her 6th bottle (6th month) of Neuralli.  I was going to come back after three months and post about our experience, but wanted to extend our trial period to provide more thorough feedback.  So now it’s been 6 months and, as promised, I’m back to share our results.

A few details about my wife and I first:

1. My wife was diagnosed with PD 12years ago.  I am her husband and caretaker.

2. Her symptoms from the beginning have been her right side is weaker than her left and she sometimes catches her right foot while walking as a result.  She very occasionally has shaking in her right leg, but typically this only happens when her medication wears off.  She really has no dyskinesia or dystonia to speak of so we’ve been lucky in this regard.  A few years ago she was diagnosed with SIBO and was given two courses of a powerful antibiotic called Xifaxan which got rid of the SIBO, but she still suffered from IBS symptoms like constipation, gas and bloating afterwards.

3. Her main problem now is her response to the levadopa/carbidopa medication.  She has slowly required more pills more often during the day. She was taking about eight 25/100 pills between 7:00AM and 10:00PM and 2 Sinemet CRs at night before bed. A year ago we added amantadine 100mg (1/2 pill, 2x daily)

4. Her symptoms present as fatigue, slowness, stiffness, etc. if her medication dosage is too low and as agitation, overstimulation and unstable walking if it’s too high.  This is referred to typically as LID (Levadopa Induced Dyskinesia), but my wife doesn’t really have much noticeable dyskinesia.

5. Other than levodopa/carbidopa 25/100, amantadine 100mg, and a few basic supplements, my wife doesn’t take anything else for her PD, with one notable exception which I’ll discuss next.

L. plantarum PS128:

“Lactobacillus plantarum PS128 (PS128) is a specific probiotic, known as a psychobiotic, which has been demonstrated to alleviate motor deficits and inhibit neurodegenerative processes in Parkinson's disease (PD)-model mice. We hypothesize that it may also be beneficial to patients with PD based on the possible mechanism via the microbiome-gut-brain axis.”

The Add-On Effect of Lactobacillus plantarum PS128 in Patients With Parkinson's Disease: A Pilot Study

frontiersin.org/articles/10...

L. plantarum PS128 - published peer-reviewed research - Clinical Studies

benedlife.com/pages/publish...

One last thing I want to clear up for folks in the United States before I share our results.  BenedLife has a patent on L. plantarum PS128 in the US under the brand name Neuralli.  If you’re in the US, you can get L. plantarum PS128 from other countries under other brand names, but by the time you add shipping, the cost will far exceed what you will pay for Neuralli in my experience.  Also, L. plantarum PS128 should ship refrigerated.  That’s not going to happen if shipped internationally. I had to do a lot of research to arrive at this conclusion, but feel free to prove me wrong.  So here’s your source for L. plantarum PS128 in the US: benedlife.com.  Sure wish I’d known this before scouring the internet for hours looking for cheaper foreign sources.

Now to the purpose of this post, our experience with Neuralli aka. L. plantarum PS128:

There is no doubt in our minds that Neuralli is helping my wife in multiple ways.  Btw we have been very strict in our testing by not introducing any new variables or changing her existing protocol in any way.  We apply a scientific rigor and skepticism when we try a new drug, protocol, or supplement.  We chart her progress as we go.  We cannot explain the positive results we are seeing other than the introduction of Neuralli.

Clarity of thought and focus

- The first result we observed after about a month was an improvement in clarity of thought.  My wife takes Neuralli at 7:00AM and 7:00PM every day.  We have definitely seen an improvement in clarity of thought in the mornings, specifically verbal communication and cognition.  We talk about important issues in the morning now and she has a complete understanding, focus and easy communication that used to take much later in the day to achieve.

Calmness

Along with clarity of thought she has experienced a sort of calmness we have not seen in years.  A more stable, peaceful demeanor has developed.  Delboy381 said it about his experience and we agree.  She simply feels more “normal”, as unscientific a statement as this may be.  All I can tell you is.  She’s herself again; best way I can describe it.  

IBS Symptoms

The most dramatic effect – and only after month 2 - is that her IBS and constipation symptoms dramatically improved.  She used to take Miralax every night before bed to be able to go to the bathroom the next day.  Now she rarely takes it at all.  Every morning she goes to the bathroom once or twice.  The diarrhea, constipation, gas and bloating have all but disappeared.  None of the dietary changes or drugs she took for SIBO or her IBS previously have worked as well as Neuralli.  And again, we know it’s Neuralli because she hasn’t introduced anything else or made any other changes.

Improvement in overall PD symptoms and medication requirements

There’s has been an overall improvement in her PD symptoms.  I think this comes from the fact that when your gut, and consequently your immune system, starts to heal, you feel better in general.  She now has more energy to exercise due to the healing of her IBS symptoms.  Her motor symptoms – dragging her right foot while walking and occasional stumbling - have improved. This took about 3 months.

The other thing that’s happening is her need for medication has been decreasing.  At first, we didn’t see a pattern in her daily medication requirements, but now we see in the morning, when she used to immediately require Sinemet upon waking at 5:30AM, she can now sleep until about 7:00 without any medication until she takes her first Neuralli with Sinemet at 7:00AM.  This alone is remarkable.

Also, she takes Sinemet about every 2 hours during the day, but now we’ve been able to cut her pills in halves and quarters and give her less medication as a result.  We’ve seen a change of .25 of a pill here, another .50 of a pill there at various times throughout the day, and yet she has the same or more energy. We’re down to about 6 25/100 pills on average a day now. These findings are very promising considering her trajectory was more pills, not less.

Conclusion

This is where we are after Month 6 and counting.  We are so used to disappointment that we hardly ever use the word improvement anymore, but factually documented improvement unaffected by any other variable other than Neuralli is taking place.  I have no idea what you will experience, but if you ask me if Neuralli is worth a try, I would say yes for sure, especially compared to all the other nasty drug alternatives out there.  Hope this review was helpful.  Any questions, please let me know.

delboy381 profile image
delboy381 in reply toJackAubrey

Thanks Jack for the testimony. I'm glad the symptoms have improved at your wife's. Do you plan to continue consumption or?

Farooqji profile image
Farooqji in reply toJackAubrey

Thanks for the candid feedback. Please keep updated in future as well

JackAubrey profile image
JackAubrey in reply toFarooqji

Thank you! I wish you the best and will continue to post updates.

Margot59 profile image
Margot59 in reply toJackAubrey

Hi,

you state that your wife drank probiotic ps128 at 7:00 a.m. and 7:00 p.m. Did she drink it in the morning together with Sinemet? Did she make sure to take it half an hour before the meal? Are there any side effects when drinking with L-dopa? Did you have a protocol? Thank you and best regards.

JackAubrey profile image
JackAubrey

Hey delboy, for sure we are continuing. We're on a 3 bottle subscription plan every 3 months and recently started month 7. We'll probably never stop taking it, unless the effectiveness decreases or we experience side effects. Not likely with a probiotic though.

Rccoble profile image
Rccoble

Wondering if you're still taking the PS128 and if you continued to have positive results. I don't see any recent update but am considering ordering it.

clarksdocs profile image
clarksdocs

Where can I buy / what is cost / thanks clark I have read recent posts they claim 3 drifferent strains help parkinson's / you'll taking only one strain

Smich profile image
Smich in reply toclarksdocs

Found this recommendation in the thread.... beopanax.com/sr/proizvod/se...

I am just ordering 3 boxes for now. Cost RSD 8,940.00 (Serbia) works out to around £65 for 3 boxes of 30 caps. Its a Serbian website so had to do Google translate.

Smich profile image
Smich in reply toclarksdocs

Just got an email from them, turns out they do NOT deliver outside Serbia 🤷‍♀️

Margot59 profile image
Margot59

Hello, has anyone had constipation as a side effect of taking ps128? How did you solve it? Thank you and best regards, Margot59.

Margot59 profile image
Margot59 in reply toMargot59

If anyone is following this thread, I want to say that I solved my constipation problem by taking 2 tablespoons of ground flax seeds and mixing them with yogurt every day. Best regards, Margot59.

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