Best diet for brain hypometabolism?

[Mau1997]

I see a discussion on how to improve brain metabolism, but I don't know which one is true? Should a low carb o ketogenic diet be used to reverse insulin resistance and improve cognitive function?

[JayPwP]

WRT brain fuel, there are only 2 options: Glucose and Ketones.

Insulin resistance means impaired glucose uptake into cells. That leaves Ketones as the only option for feeding insulin resistant cells.

[Michel0220]

Hi Mau. The following presentation might be of interest. youtu.be/iBNNIIDBIYU(Not working as expected?)

[Peter-Jan]

Are there people here who have experience with metformin for their PD? Do neurons respond to metformin to improve brain hypometabolism?

[Peter-Jan]

From my experience I would advise a ketogenic lifestyle. Here's what I do myself: ketogenic diet, regular fasting for several days, never eating breakfast and OMAD. Supplemented with MCT oil (C8) 3 to 4 times a day. The goal is to get ketone levels up. You can also measure this with a glucose/ketone meter. My guideline is above 1 mmol/l ketones. I don't (yet) do exogenous ketones

[JayPwP in reply to Peter-Jan]

Isn't MCT oil exogenous ketone?

[Peter-Jan in reply to JayPwP]

As far as I know MCT oil is an oil that it is quickly metabolized into energy by the liver. By exogenous ketones I meant ketose esters and ketone salts.

[JayPwP in reply to Peter-Jan]

I understand that MCT oil is converted into ketones by the liver. But I get the point

[Peter-Jan]

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