Melatonin for PD

[Victor1975]

Is anybody using Melatonin for PD?Dosage?

Any brand recomended ?

Results?

[alexask]

I think many are. Myself 20 mg per night. I just use Piping Rock as by far the cheapest. Seems to help me.

[Juliegrace]

if you search it in the Cure Parkinson’s Community you will find numerous posts.

[Michel0220]

Hi Victor

I recommend PharmaNord sublingual melatonin. Sublingual acts faster and smaller doses are required. I take one pill just before going to bed and another one if/when I wake up in the middle of the night.

[jeffmayer]

I thought melatonin was a sleep aid

[alexask in reply to jeffmayer]

Oh it's so much more than that. See my previous posts

[whitdemo in reply to alexask]

Its a sleep aid and an antioxidant

[JCRO]

chartist posts often and knowledgeably on the subject. I take 15mg of life extension 3 mg pills every night. It helps me sleep but other benefits may accrue. chartist ’s body of work will inform. Good luck.

[WhyRBD]

I have used diet alone to eliminate RBD events and deliver an amazing night of sleep. I am in prodromal PD, but just might work for everyone

[Ghmac in reply to WhyRBD]

Can you share your diet?

[jimcaster]

JCRO is correct. chartist has written several informative posts regarding melatonin being much more than a sleep aid, particularly in high doses. I take 120 mg per night. In addition to helping me sleep, I believe it has enabled me to delay my first dose of carbidopa levodopa by two hours each morning.

This is from Chartist's Melatonin for Parkinson's Disease (part 2) post:

"Dr. Neel, Dr. Reiter and Dr. Shallenberger (74 years old) all use melatonin at 100 mg /day or higher for extended periods of time. Dr. Neel uses it in his Covid-19 patients very successfully at 1 mg per kilogram! Dr. Russell J. Reiter is a world renowned melatonin researcher who has been involved in over 600 studies and uses it in his animal studies and himself @ 100 mg+/night for 25 years as a preventative and he is in his 80's. Dr. Shallenberger uses it in all of his patients and himself @ 180 mg / night and up to 360 mg/ day in some of his stage 4 cancer patients. Some researchers are considering over 500 mg/day of melatonin for Covid-19."

[Schofield81]

where can you buy such high strength melatonin to take it in such high doses ?

[jimcaster in reply to Schofield81]

I order this through Amazon. I take two capsules nightly.

Photo of Melatonin Max bottle.

[Schofield81 in reply to jimcaster]

I’m in uk. Struggling to find anyone that ships it

[LAJ12345 in reply to Schofield81]

evitamins.com/max-strength-...

Will these people ship it to you?

[Schofield81 in reply to LAJ12345]

no unfortunately they won’t ship to uk. Strongest I can find in uk are 5mg

[Esperanto]

Usually, researchers do not mention the type of melatonin. Sometimes, however, prolonged-released is used, as in the study below. Apart from the difficulty of availability, can anyone tell me more about the difference in effect and application of Melatonin PR?

ncbi.nlm.nih.gov/pmc/articl...

“Effects of melatonin prolonged-release on both sleep and motor symptoms in Parkinson's disease: a preliminary evidence”

[Hidden]

I’ve been taking melatonin for almost a week now at night and I’ve had nothing but negative results, horrible dreams and talking in my sleep and I even fell out of the bed after dreaming someone was chasing me. Not taking it anymore!

[chartist in reply to Hidden]

Not everyone is able to tolerate supplemented melatonin, especially at high dosing levels. If you use natural ways to boost your melatonin levels, you can avoid the unwanted side effects that you are reporting. I wrote about how to boost melatonin levels naturally here :

healthunlocked.com/cure-par...

Art

[Hidden in reply to chartist]

I only took 10 mg. Never again

[chartist]

Here are a few very good reasons why people with PD might consider melatonin as part of their supplement regimen :

healthunlocked.com/cure-par...

I have been at 132+ mg of melatonin for months now.

Art

[rhyspeace12]

My husband started sundowning and ended up in the emergency room with hypothermia after heading out in the middle of the night and ending up face down in the dirt in a field on our property. I stopped his sundowning immediately by giving him 10 mg of Melatonin at 4pm and another 10 mg at 9 or 10pm. The only time he ha a problem again was when my son didn't give him the first dose until 6pm. All the brands I used worked.