new book on lithium

[gaga1958]

My friend sent me a link to this new book on PD and lithium.

amazon.com/Promise-Lithium-...

[Discogs_discogs]

Has anyone here taken lithium? If so, was it before PD? If it was after your diagnosis, did lithium help your symptoms or halt them?

[Jebbie12]

I took littium orate 20 mugs for about a year and a half. I did feel it helped a little bit not dramatically though. But I have to say I am 14 year since diagnosis and I’m doing very well. I attribute that mostly to seven days a week of exercise.

[bassofspades]

Lithium is AMAZING! Cleared my chronic brain fog right up. 15mg Lithium Oratate per day for me. Drink some Pelligrino!

[Discogs_discogs in reply to bassofspades]

Bassofspades, was brain fog removal the only difference that you noticed? .... Any others?

[bassofspades in reply to Discogs_discogs]

That's all but for me, it was a miracle! Night and day difference!

[Bolt_Upright]

Here is a podcast with Dr. Guttusso: podcasts.google.com/feed/aH...

[NRyan]

Is the author recommending Lithium Carbonate or Lithium Orotate?

[BeedieBird in reply to NRyan]

I've read the book and he prefers Aspartate over orotate - better absorption. he is a fan of micro dosing - 5mg to start.

[alexask]

If there is a consensus on here it's for low dose lithium Orotate. I take it sporadically - I think it's helpful

[BeedieBird]

I believe today is the last day the ebook is on sale for .99. Def worth the read. He's a fan of low dose lithium. Aspartate over Orotate due to better absorption according to his personal studies. Hard to find Aspartate. Only one company sells it - Solaray.

[JayPwP]

Worth checking serum lithium levels periodically

"The effective dose range for lithium is 0.6-1.0 mM in serum and >1.5 mM may be toxic. Serum lithium levels of 1.5-2.0 mM may have mild and reversible toxic effects on kidney, liver, heart, and glands. Serum levels of >2 mM may be associated with neurological symptoms, including cerebellar dysfunction. Prolonged lithium intoxication >2 mM can cause permanent brain damage."

pubmed.ncbi.nlm.nih.gov/195...

[JayPwP in reply to JayPwP]

No comments???

[CaseyInsights in reply to JayPwP]

Your observations are linked to use of prescription level usage - 450mg to 600mg Lithium Carbonate per day.

Micro does of Lithium Orotate - containing 10 to 20 mg of elemental Lithium - would not warrant such testing. 🌹

[JayPwP in reply to CaseyInsights]

Thanks for the information

[gaga1958 in reply to CaseyInsights]

In his book, The Promise of Lithium by Thomas Guttuso MD, he states that lithium asparate not orotate is the better form to use based on a number of criteria he goes into.

[CaseyInsights in reply to gaga1958]

Thanks! I have read the book and opinions differ.

The form recommended by Dr. Laurie Mischley is Orotate and I will stick with that. 🌹

[JayPwP in reply to CaseyInsights]

In case you are still taking it, please let me know the time and method you consume lithium orotate? Also if you know of any contraindications to note before starting.

[CaseyInsights in reply to JayPwP]

I know of no contraindications. Take it with the night/last supplement stack of the day.

[JayPwP in reply to CaseyInsights]

Thanks. Started with 5mg lithium orotate yesterday night.

[gaga1958 in reply to CaseyInsights]

Do you recall how Dr Mischley views the cancer concern of lithium orotate which is why Dr Guttuso recommended lithium aspartate.

[CaseyInsights in reply to gaga1958]

Do you recall how Dr Mischley views the cancer concern of lithium orotate…No! I am not aware of such. Do inform 🌺

[gaga1958 in reply to CaseyInsights]

If you still possess that book--The Promise of Lithium, on page 118 at the top he says, " I was surprised by what I found upon searching on the safety of orotate use. Several studies in rat cancer models have shown short-term daily oral orotate supplementation to increase liver, breast, kidney, sm intestine, and lung cancer occurrences."

He goes on to elaborate on how he looks at the dose/duration of taking orotate that may cause cancer to increase in people compared to rats.

Then he says. "Because of the remote possibility that long-term daily orotate intake could increase cancer in humans, even at 12% the dose shown to increase cancer in rats, I decided that lithium aspartate would likely be a safer choice for our studies as long as there were no safety concerns with daily aspartate intake. "

[CaseyInsights in reply to gaga1958]

What’s presented here is Dr. Guttoso views, not Dr. Mischley.

So you still have not presented evidence on how Dr. Mischley views the cancer concern of lithium orotate.

And do note (in the extract you presented) Dr. Guttoso speaks of the “remote possibility that long-term daily orotate intake could increase cancer”, and this from very limited research on this molecule.

I remain unperturbed 🌹

[gaga1958 in reply to CaseyInsights]

sure, I just wondered if Mischley addressed it and what her rationale was. I cannot present Mischley's view point as I have not read/heard it.

[JayPwP]

Parkinson’s Disease: Potential Actions of Lithium by Targeting the WNT/β-Catenin Pathway, Oxidative Stress, Inflammation and Glutamatergic Pathway

ncbi.nlm.nih.gov/pmc/articl...

[gaga1958]

I guess I haven’t read enough yet to understand how much an mM is compared to mg to know how much danger this really is

[JayPwP]

What is the best time for taking lithium?

[gaga1958 in reply to JayPwP]

That is a chartist question. he is the expert.

But, in the book, "The Promise of Lithium", by Thomas Guttuso, Jr., MD, I did not notice him mentioning a time of day. But maybe I didn't get into the weeds deep enough to see it. He discusses which type of lithium and amounts but didn't notice a particular time of day. Its a small book on Amazon if you want to purchase, $16.

[gaga1958 in reply to JayPwP]

In his book, The Promise of Lithium by Thomas Guttuso MD, he states that lithium asparate not orotate is the better form to use based on a number of criteria he goes into.

[JayPwP in reply to gaga1958]

Thank you

[jimcaster]

I missed this when you first posted it. Thank you for sharing!