The PBM was administered transcranially with a VieLight Neuro Gamma device (4 LEDs, 240 joules), intranasally with a VieLight Gamma nasal device (1 LED, 15 joules), transdermally to the C1/C2 region of the neck and to the abdomen with an Irradia MID 2.5 laser device (4 laser diodes, 39.6 joules) or a MIDCARE laser device (2 diodes 39.6 joules).
Methods
Twelve participants with idiopathic PD were recruited. Six were randomly chosen to begin 12 weeks of transcranial, intranasal, neck and abdominal PBM. The remaining 6 were waitlisted for 14 weeks before commencing the same treatment. After the 12-week treatment period, all participants were supplied with PBM devices to continue home treatment. Participants were assessed for mobility, fine motor skills, balance and cognition before treatment began, after 4 weeks of treatment, after 12 weeks of treatment and the end of the home treatment period. A Wilcoxon Signed Ranks test was used to assess treatment effectiveness at a significance level of 5%.
Results
Measures of mobility, cognition, dynamic balance and fine motor skill were significantly improved (p < 0.05) with PBM treatment for 12 weeks and up to one year. Many individual improvements were above the minimal clinically important difference, the threshold judged to be meaningful for participants. Individual improvements varied but many continued for up to one year with sustained home treatment. There was a demonstrable Hawthorne Effect that was below the treatment effect. No side effects of the treatment were observed.
Conclusions
PBM was shown to be a safe and potentially effective treatment for a range of clinical signs and symptoms of PD. Improvements were maintained for as long as treatment continued, for up to one year in a neurodegenerative disease where decline is typically expected. Home treatment of PD by the person themselves or with the help of a carer might be an effective therapy option. The results of this study indicate that a large RCT is warranted.
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PDWarrior1900
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Thank you very much for this post PDW. I have been using the Coronet since December last year, two sessions of 24 minutes per day. It is hard to attribute a specific improvement of my symptoms to this only, but I have a strong feeling that it is stimulating my brain which can only be a good thing!Did you not also post a video that was showing that it's not supposed to work as the light doesn't reach to the brain? Sorry if I'm wrong.
sorry, 'i' don't believe in the coronet... but i'm very glad to see that it is helping you... I also did not believe in the coronet until i read this legit scientific study... BUT... it required '3' devices on the PDP to see results...2 different vielights (one on the brain and the second one intra-nasal and the third was place on the stomach using a device manufactured by another company)... although I've done research on the coronet... i've yet to see even 'one' credible study on it...
*i meant to say that i did not believe in the 'vielight'... until i read this legit science study (but it also had only a small handful of participants... but it was still a credible study)
There was a study on the coronet and Therapad done in Australia last year.Discussed it with our neurologist, who said the team and the team leader are highly thought of and it can be assumed that the results were legitimate. Some of his patients are using it independent of him. Some with very good results.
My husband uses both the coronet and the Therapad. His jerking legs at night have calmed down, thank goodness 👍
if you read my other posts and watched the investigative video from two top medical researchers.... you'll know why i am convinced that the coronet (and all the other cheap red light devices) are a crock of B.S. .... they are too weak to penetrate the skull. Period.
Thank you very much for this clarification PDW. I had the pleasure of interviewing the creators of both the Vielight and the Coronet devices. You can see recordings of those interviews on our YouTube channel: youtube.com/channel/UCN2A0v...
that's very good thanks... but i think you'll agree that there is a BIG difference between a $300 "toy" that is less than 1 watt in power vs. the vielight and other devices that cost THOUSANDS
Hi PDW, great info, thanks. I'm not sure what device you are referring to as a "$300 toy that is less than 1 watt in power", but it sure does not sound like the Well Red coronet, which costs quite a bit more, and whose spec sheet quotes an average whole head irradiance of 6.9W for the 670nm cycle and 2.67W for the 810nm cycle.
Doesn't the Vielight irradiate only small sections of the skull? Do they quote the average whole head irradiance? Anyway, the results of the study you quote are indeed encouraging, which is excellent news, thank you.
Thanks for posting the above studies. We have also watched the interviews with Catherine Hamilton on the red light hat. I have also posted a lot about the red light hat and my husband if you click on my avatar.
My husband as well as quite a few others here use the coronet. My husbands started with the mens shed one then earlier this year bought the coronet. We also have the abdominal therapad but not used that on a regular basis.
He uses the coronet twice a day for 24 minutes a day.
It’s hard to attribute what differences to PD it makes but some symptoms are lessening like hallucinations at night, not had those for a while. Meds not changed for 2 plus years in fact less pills taken.
Neuro says you must have a milder case of PD, we think it’s all the additional things he does.
I don't want to go on about this, PDW, but I don't know where you saw the less than 1 Watt on the Coronet Duo spec sheet. We have both looked at the same sheet, and you have quoted the same figures I have. The key section is on page 2, and on the fourth line of the table the descriptor is "Average whole head irradiance (W)" The (W) means that the units are in Watts, and the numbers on that line are 6.9 Watts for 670 nm and 2.67 Watts for 810 nm.
also, i posted a video from 2 researchers, one of whom is an M.D. -- look for that post...it clearly shows that these low wattage devices do NOT penetrate the skull
1. If you really mean to make your point clear, how can you ask someone to start searching for your post where you posted something? Its your post, why can't you just include the link in this current post? If you don't have the time to get your post why should someone else have the time?
2. Also Winnie asked a simple question, which is what I also had in mind... Is the output of one LED the same as 45 LEDs? This required a simple one line answer but you failed to answer it
3. So the Coronet definitely cost more than twice $300 or £300, its several LEDs combined is way greater than 1 watt and many of us long term users, including me, have mentioned to you that its helped us one way or another... So what I don't understand is why you are bent on breaking your back to describe the Coronet as a $300 toy producing less than 1 watt?
first, i'm not trying to be disagreeable with anyone... we all suffer from PD and we all want relief... reversal... a cure... That said, whatever you guys think works for you... great! I've done a lot of research on my own on just about every aspect of PD and all the various therapies, etc (and i'll bet you guys have done the same thing, right?) ...
To answer your question (and i am not a scientist or math guy, etc... just some schmo with PD).... If a 'single LED' is too weak (under '1' watt) to penetrate the skull... what difference would it make if the therapy gadget had a 100 or 1000 or even a MILLION of those 'same' LEDs? ... NONE of them is penetrating the skull, as far as i'm concerned--------------------------------------------------------------
Common sense tells me that there must be a BIG medical difference between the $5,000.00 Vielight... the $10,000 Cognitolite (not sure if that's the exact name) ... and the .... '3' hundred dollar coronet toy...
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If the coronet really worked... where is the extensive, double-blind controlled study to support its positive therapeutic effects?
Not that i agree that its been established that naked eye visible light needs to 'penetrate' the skull, but its baffling that you cant comprehend the impact of aggregating multiple LEDs. Next time you drive past, or better yet attend, a stadium at which 4k tv broadcasts originate, take a look at one of the light arrays. It aint one giant bulb.
To everyone here... this is my LAST comment in this thread.... I don't have time to keep repeating myself... I have recently had several posts on PM (photobiomodulation) with LINKS for clinical trials and RESEARCH videos....
I sincerely hope all of you have improving health whatever modalities you use...
but i'm no longer replying to anything else in this thread... Time to move on guys!
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the coronet is a worthless toy ....
it does NOT penetrate the skull ... let alone reach 3 inches into the brain to affect the substantia nigra ...
I've read your anecdotal comments that it is helping some of you sleep better -- GREAT!
I've never read (and I've researched this thorough here and on StuffThatWorks.com and Google, etc.) AND... I've exchanged several emails with CATHERINE HAMILTON on the coronet...
There is NO HARD CLINICAL EVIDENCE that the coronet works (ditto for just about every other PMB toy out there.... EXCEPT... the clinical study using '2' Vielights and a 3rd PMB device (at the same time!!!) on PDP that does show significant improvement in symptoms)
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i've posted this video multiple times... WATCH these two researchers from the "Neuro Laser Foundation" DE-BUNK low-level red light therapy... one is an M.D. and the other is a DC
I use the 'sun' 3 to 5 times a week for my PMB treatments.
The 'sun' DOES penetrate into the skull far enough to stimulate the mitochondria of our brain. The 'sun' (in moderation) does other amazing things for our health
If you're so busy that you don't have the time to reply then don't keep posting rubbish baseless stuff
Go and read up on how analogue radio tuning works. Light is also EMW so it works the same way. I'm not an electrical engineer but I read up on these things
You are mistaken. On several counts. Just because the first clinical study used a particular device doesn't mean only that device works. It means that device was chosen in the first trial that took place
It always rains when the pavements are wet
A while back exanatide was the only glp1 receptor agonist to have been in a clinical trial for PD. By your logic, it's the only one that works. ???
The vielight doesn't cut through like a laser. The measure that matters is light per cm2 or total light on the skull. The answer to my question is that the coronet would trip a 500ma fuse. It's total power consumption exceeds the vielight. And it is deliberately de-tuned to stop it getting too hot. Light intensity is cumulative. Led torches and car headlamps rely on that.
This is from a research project on the subject
Results are presented as absolute values in milliwatts/cm2, as well as in percentages. Relative penetration percentage values were calculated using the following formula:
Transmission of Near Infrared and Red Light through Cadaver Skulls
The results of the transmission of light through cadaver skulls in coronal section are presented in Table 1 in absolute values and in Figure 2 in relative penetration percentages. With the light source and light meter placed 5 mm away from each other (the approximate thickness of skull bone), 35.1 mW/cm2 of near infrared light and 72.6 mW/cm2 of red light reached the light sensor. These values served as baseline for the percent penetrance calculated.
A couple of quotes from the trial you are so excited about may help you better understand why your assumption about the coronet being a toy due to poor penetration could be invalid
Because PBM acts at a cellular and mitochondrial level, the therapy has been shown to have a multitude of beneficial effects in the body
In addition to the local effect of PBM on target cells, PBM also has a systemic effect [14,15,16,17,18] and a delayed effect due to activation of DNA transcription factors [8, 9]. One of the primary downstream effects of PBM is on immune cells, producing an anti-inflammatory effect, which has profound consequences for many body processes
Also, on the theme of it always rains when the pavement is wet, the trial you quote used nose, head, neck, and abdomen administration. Since that is the only trial published by your logic only that combination works and individually the vielight devices are toys
Moreover , the limit of penetration into the brain is a couple of centimetres. That won't reach the substantia nigra of a human (it will reach the SN of a mouse) so it is exceptionally unlikely that photobiomodulation as a PD therapy is a direct action on the dopamine neurons
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