Intermittent Fasting 16/8 DOESN'T WORK For Humans

[Bolt_Upright]

(Edit: I want to add that 16/8 DOES work for losing weight (mostly because you eat less), and I think it helps focus your attention on what you are eating and gets your digestion into a "cycle" instead of always piling more food into the system. I think the point of the video is that it does not cause autophagy)

So those little rodents they based 16/8 intermittent fasting on have metabolisms 16 times faster than ours. Watch the video, I think it said we have to fast a week to get the same effect as a rodent fasting 16 hours. But he does mention eating according to the circadian rhythm (eat when the sun is out). youtu.be/zC9_g01disc(Not working as expected?)

[Hidden]

Have you heard of Valter Longo? 30 years of research. Or are you asserting this based off of one video

[Bolt_Upright in reply to Hidden]

Well... I have been intermittent fasting for about 2 years now. I know it does work for losing weight, but I think it works like he explains. If I eat in an 8 hour window, I eat less.

I also think the 8/16 diet helps with ketosis. I seem to stay in ketosis (last time I checked).

But it is odd, I had just heard the other day how 8/16 does not get you the autophagy. And then today I saw this video and decided to share it.

I plan on trying a 24 hour fast next weekend and see how that goes. Maybe with some meditation! youtu.be/9h4GiblYrPk(Not working as expected?)

[Bolt_Upright in reply to Hidden]

Yes, I Googled Valter Longo. I have seen him before. Mimicking fasting. I have heard of that. Interesting.

[Bolt_Upright in reply to Hidden]

Here is a great article on Valter Longo. It is fairly positive although it does mention there is a cost to this diet. But lots and lots of good information (and photos of mice): statnews.com/2017/06/13/fas...

[jeeves19 in reply to Bolt_Upright]

Bolt. You appear to have the right habits, determination and will to be the guy the rest of us could count on as regards fasting. Why not give the 72 a go? I did a 10 days once but seem to lack the self control that I used to have.

[Hidden]

Dr. Ana Maria CuervoI’ve mentioned her many times

72 hour fast to clear away toxic proteins

[Bolt_Upright in reply to Hidden]

Yes! 72 hours sounds about right!

[Hidden in reply to Bolt_Upright]

She says a minimum of 72 which my logic agrees with.Eating according to sleep wake cycle makes sense. I have been eating typically from 9-2 daily. I have been watching my family eat dinner for over a year.

It is the pits!

[carrow_road]

I am taking part in this study: clinicaltrials.gov/ct2/show... Earlier this month I was fasting for a week (Buchinger type). I lost about 4 kgs in weight, my blood pressure was maintained with 50% of normal meds and my tremor significantly reduced . UPDRS score improved by 4 points after fasting. compared to before. After fasting they put us on intermittent fasting for a year (prefeably 16/8 , but they said that 14/10 would be ok as well) for at least 5 days a week, also plant based diet. I dont feel a large effect the intermittent fasting except for maintaining the weight. I had to slowly return to my normal blood pressure medication. During the real fasting i felt more mentally balanced.Also during fasting week no supplements were permitted, now slowly starting B1 again.

[Mimilemew in reply to carrow_road]

Hi! Can you please elaborate more on how your week long fasting was? What did you eat, between what times, etc? The results sound great but my PD husband is already skinny and I don't want him to be underweight. Is there a way to reap the benefits without the weight loss?

[carrow_road in reply to Mimilemew]

The first 2 days were a bit tough, then I got into some sort of "fasting high" where I felt quite well, actually . I had no desrire to eat , even when baking bread for the family. I took around 350 cals/day , but recall that the slimmer folk in my group were advised to have around 500 cals/day , all from from juices and broth. It is an interesting experience to eat 1 /2 pint of beetroot juice slowly with a spoon. After a week most of the group were so much into it that they asked to carry on for a few more days. The study design did not allow though. Typcially the weigh loss during fasting is not of a concern, as its added again quicky, when returning to a normal eating pattern. medisana.com/healthblog/buc... hope this helps.

[dadcor]

Only fasting alone in whatever form, may have some positive effect on PD, but not that significant. It should be combined with a diet (for example low carb or even no sugar..) and also with a serious exercise program. This s the way...

[jeeves19 in reply to dadcor]

How do you know?

[jeeves19]

Very interesting 🤔

[NellieH]

Disclaimer first: I am not a PWP; I'm here because someone I love is.Response: wish it worked for PD, but it can be otherwise helpful, too. After about 5 months of IF 16/8, my a1c dropped from 5.8 mmol/l, approaching pre-diabetes, where it had been for a few years, to 5.5.

[Hidden]

BRAIN HEALTH, FASTING WORKs in some important ways. What the video states makes a lot of sense but a key point he fails to address is the effect frequent insulin elevation or spikes has on the brain. The less frequently your insulin is spiked, the better for your brain. This is a way that fasting is beneficial. And what about the gut lining? That was not addressed either? Although a meta analysis, it is not the whole picture and therefore asserting “intermittent fasting doesn’t work” especially to a population who can benefit from it is not good Bolt.

I’m very wary of people following the lead of anyone else based on what really is very little research.

Bolt, I respect and appreciate you but this sort of thing concerns me.

[psyche100]

I practise IF, eating between about 2 pm and 8 pm. The point about rodents' faster metabolic rate is interesting, and I may try out longer fasts.

I'm less convinced by the evidence (the studies by McHill and Jamshed) about eating in the morning rather than the evening. McHill did find that food intake later in the day was associated with higher weight. However, the finding is only correlational - i.e. people with higher body fat might be more prone to late night snacking (which may not be the cause of their higher weight). Also, the high body fat participants consumed most of their calories only 1.1 hours closer to melatonin onset than the low body fat group.

Jamshed found benefits of early TRF (eating between 8 am and 2 pm) including on evening BDNF levels (particularly interesting for me as I have PD). However, the control group were not doing TRF as they ate between 8 am and 8 pm. Dr Stanfield rather glosses over the lack of a proper control (TRF according to my schedule) by saying ‘compared to a more unrestricted strategy’.