Fasting and intermittent fasting are the keys to recycling the garbage in your cells and turning it into the raw materials to build new healthy cells. You can take the amyloid plaques that are killing your dopaminergic cells and causing your disease and turn them into amino acids that are then used to repair yourself. The research on this won the 2016 Nobel prize in medicine. In the video, Dr Berg spells it out in very easy to understand terms.
Discuss!
The problem is to get what is toxic out of the body: urine, sweat or faeces?
I dont see the problem. These processes dont stop during autophagy.
They go out with the activity of the lysosome, they go back into circulation, and if they are not expelled in quantity, they are there. The problem of Cell Life is to live and operate with what it finds and if, for example, it does not find vitamin C in the necessary quantity, it chemically solves the deficiency using something similar but sometimes toxic. She has this ability.
My opinion is that it is better not to have deficiencies of useful substances in order not to give this choice to the cells.
But I don't know, I'm not a biologist, ask them.
Biologists have already figured this out. You could watch Yoshinori Ohsumi explain his research here. I guarantee it will cure one thing just by watching it - insomnia!
Love you Gio! 😎
Extra LOL !
Gio, as per Dr Berg, the lysosome recycles the toxins and turn them into good fatty or amino acids for the cells reconstruction.therefore the body won’t be exposed to the toxins after they entered to the lysosome.
Exactly Kia! There are various ways to activate the function of the lysosomes, but my imagination leads me to believe that it would be better not to do in deficiency, but on the contrary. This way the body will replace toxic products with good substances. But it's just imagination, so it's better to hear biologists. (As Bassofspades published above). I only know that substances such as DDT remain in the bodies for a long time and sometimes come back into the circulation again giving their symptoms. I've used some sort of pesticide stuff, and at that time at the agrarian school they told me to drink the fat milk that would help me. True, but fats remain with toxic substances and accumulate over the years. this is the real problem today.
PS. Fasting or intermittent fasting does not necessarily mean a lack of something, the body has its reserves, just as feeding badly can lead to shortcomings.
Kia, in my imagination of how fasting and autophagy works I thought that the unused residues of tertiary lysosomes would be better expelled before they settle in fat. For this I would soon follow a bit of physical activity, drinking a lot of water so as to sweat and urinate a lot in the short. the high activity of the lysosomes always requires a good integration of all the vitamins and minerals given the high number of enzymes and coenzymes that are activated. Pure personal fantasy as always.
For those who love these things:
Although I do not fast, it feels a lot healthier to let myself get hungry before eating. If it is mealtime and I am not hungry it feels much better to wait. Starting at about minute 20 in the video below discusses the importance of alternating between the fed state and the fasted state:
Agreed autophagy is important – if we people with Parkinson's could get that to work right it would clean up the troublesome alpha-synuclein.
One correction to the video – the amyloid of Alzheimer's is a response to infection. Hundreds of millions of dollars have been wasted in a fruitless pursuit of reducing amyloid instead attacking the underlying cause. For information on this see here:
statnews.com/2018/10/29/alz...
Fascinating!
That’s very interesting. Thanks!
I bought some Rapamycin a couple of years ago and took a small dose for a year. Hard to say if it did any good and it was a bit pricey, but you can get it depending on where you live. It's supposed to control MTOR which can start autophagy going. Might have side effects, although many believe they appear only at very high doses.
You can also supposedly trigger autophagy by restricting the intake of the protein called Leucine, which I'm trying to do now.
Most interesting info. to analyze and apply, if one feels it might help them. Since I have been doing fasting occasionally, the last couple years, and have cut way down on portion control, and lost weight, and exercise daily, I have noticed a remarkable improvement in primarily, the motor symptoms that have been plaguing me with PD. Autonomic system symptoms and peripheral neuropathy symptoms, that I have, have not, however, gotten any better.
Great video Bass. Really well explained and taught me some new aspects of the whole autophagy dynamic. Trouble is I hate fasting although I do do it!
Dont think of it as fasting. Think of it as skipping late night snacks and skipping breakfast, the least important meal of the day! Hold off till lunchtime. Stop eating after dinner. Coffee and tea are ok. Take it easy on the carbs and it gets easier and easier over a few weeks.
Been watching fasting discussion last few days. Makes sense. Garbage disposal spits out hammer, nails and paint. Giving blood like changing oil in car.
Got on here to ask you all, about the "rules" of fasting.
Thanks bass for giving us some general guidelines we can adapt to ourselves.
I'll take it from here
I think fasting is OK as long as a person doesn't have any health condition which might make it unsafe to go without food for short periods of time. The Senemet I take kills my appetite and I have to eat when I am not nauseated from this medicine. Thanks for sharing information.
All that is pretty straight forward - intermittent fasting - who is getting best results in slowing down progression and with what intermittent fasting regime ?
Cheers
Here's my regimen, I guess you can call it intermittent fasting.
Eat organic,keto, paleo the best i can.
Skip breakfast.
No snacks.
Nothing to eat after dinner.
Of course, nobody is perfect but I try to stick to that the best I can. And the more I stick to it the better and sharper i feel. If i do eat before lunch I go for whey protein or eggs.
Ok great that’s pretty well mine except I do sneak gluten free bread and banana and coconut milk thick shakes many thanks
Mast cell activation syndrome is there a link? 
Dr. Yoshinori Ohsumi, a Japanese cell biologist, got the 2016 Nobel Prize for figuring out autophagy. Fasting. I recently have gone to OMAD.
Intermittent Fasting 16/8 DOESN'T WORK For Humans
Parkinson's disease is an autoimmune disease: An emerging viewpoint
