Glutamate is an amino acid that is produced in the body and also occurs naturally in many foods. Monosodium glutamate (MSG) is the sodium salt of glutamic acid and is a common food additive. MSG is made from fermented starch or sugar and is used to enhance the flavor of savory sauces, salad dressings, and soups.
I understand but we have no choice except to be very selective in choosing our foods.
Gluten is not the same as glutamate but they are closely related. Before we worry about mushrooms and vegetables, it is prudent to avoid MSG and gluten. There may be better videos to explain this but I quickly pulled this one up.
Glutamate is my cryptonite. One of the first things Mayo neurology told me is that my ALS was caused by glutamate excitotoxicity. A low glutamate diet wasn't recommended.
About 30% of gluten is glutamate. I've been tested several times and don't have gluten antibodies, but I am intolerant of gluten.
MSG occurs naturally in Parmesan cheese, I can't eat it at all. Same for Asian restaurants, too much MSG - most restaurants really. It's not worth the consequences to eat out.
We're 99.9% organic in our house. I'm chemically sensitive and have a lot of triggers. Clean to me means no fragrance. Staying at a hotel is torture, chlorinated/fluoridated water ☠️ People just don't get it.
The active ingredient in Roundup is Glyphosate (the principal product of my poisoning). Our food supply is contaminated with it and I know when I have inadvertently come into contact with glyphosate contaminated food.
Glyphosate is a synthetic amino acid that substitutes itself as glycine in our body - it can't tell the difference.
•Glutamate neuroexcitotoxicity appears to be a significant factor in autism, as well as in other neurological diseases and mood disorders.
•Glutamate neuroexcitotoxicity leads to excessive oxidative stress in the brain, causing hyperactivity, seizures and neuronal damage, particularly in the hippocampus—the seat of learning and memory.
•Monosodium glutamate (MSG), which is a common ingredient in processed foods, can cause seizures in mice if it is injected into their bodies.
•Glyphosate works synergistically with glutamate to cause harm.
•In different types of studies with rats, glyphosate has been shown to cause neuroexcitotoxicity in the hippocampus. This is associated with excess extracellular glutamate and overstimulation of glutamate receptors, called NMDA receptors. (See links)
•A certified organic whole foods diet is a simple step you can take that will provide protection from glutamate excitotoxicity, while also reducing your family’s exposure to glyphosate. westonaprice.org/health-top...
So if ALS (and other NDDs) is caused by glutamate excitotoxicity why don't doctors treat it? I believe that to treat an illness it requires the doctor to acknowledge the cause.
Memantine is an old drug with a good safety profile. It's approved to treat Alzheimer's. Memantine is a selective NMDA receptor antagonist, it blocks some but not all of the glutamate cell receptors, and has less side effects than other drugs in it's class. Ketamine is my first choice.
ALS is also caused by functional loss of acetylcholinesterase (AChE) the enzyme that breaks down acetylcholine (ACh) another neurotransmitter that accumulates and blocks signals between the nerve cells.
I detest the fact that the article I linked below is in the context of COVID. Stay with me - it's relevant to our topic. Ivermectin (IVM) was on my radar but I didn't know how it worked. There is a patent for IVM treatment for ALS. The Westin A Price article told me why IVM treats ALS - it acts like AChE , it breaks down the excess acetylcholine in the synaptic cleft that causes neurotoxicity.
•All symptoms seen in Covid patients can be explained as neurological impairment of the autonomic nervous system.
•Studies have shown that drugs that inhibit the sympathetic nervous system are associated with a higher mortality rate in Covid patients.
•These drugs, all commonly prescribed to the elderly, include antipsychotics and anticholinergic drugs, benzodiazepines, opioids, barbiturates, proton pump inhibitors, ACE inhibitors and other drugs to lower blood pressure.
•Acetylcholine (ACh) is a key neurotransmitter; after it is released into the synaptic space, it must be removed by acetylcholinesterase. If acetylcholinesterase is lacking, the ACh will remain in the synaptic space and the transmission will not continue.
•Microwaves and 5G affect the structure of acetylcholinesterase. When ACh is not removed for re-uptake by the neurons, the body makes more receptors for the neurotransmitters so that the sympathetic nervous system can work. Ordinarily, this can help us adjust to new electromagnetic influences, but if a person is taking the inhibitory medications mentioned above, the drugs will become toxic since the new receptors will greatly magnify their effects.
•Covid-19 patients need a reactivation of the sympathetic nervous system, which can explain why vitamin C and vitamin D, but also zinc, selenium and hydroxychloroquine seem to be beneficial.
•Ivermectin seems to mimic the action of acetylcholinesterase, thereby alleviating the damaging build-up of ACh.
It's not just IVM either, there are other anthelmintics with similar function; like Wormwood (Artemisia absinthium) and PanacurC (fenbendazole).
It's important to understand that there are universal biological processes across all forms of life; humans and plants for example both use adenosine triphosphate (ATP)it is the universal energy carrier across all kingdoms of life. We can survive minutes without oxygen, but only seconds without ATP.
Cancer, viruses (still a theory), bacteria and neurodegeneration all result from the process of oxidative stress and production of reactive oxygen species (ROS). This is why repurposed drugs show promise in treatment of other diseases.
This went way deeper than I expected 😂 I am trying to recover from my poisoning and cure my ALS....... and altruistically help those with PD to recover and cure themselves. I watched my mom suffer for years with PD without knowing how to help her. Now I have the mother of all NDDs, no one is going to rescue me - or you. Push the dogma about IVM aside and let's get to work solving the puzzle.
Silent Echoes is a tribute to Silent Spring. My avatar, the canary, signals that I am the canary in the coal mine.
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Do you really have to avoid fresh homemade bread and saurerkraut on Selegiline?
The naturally occurring molecule N-acetylcysteine (NAC) shows benefit in a clinical trial for Parkinson's Disease.
Parkin, glutamate, NAC, mitophagy
