I am from Mumbai, India. I have Parkinsons and liver disease as well.
I am on various facebook groups. There people recommend using Allithiamine TTFD.Its a disulfide derivative of Thiamine...
Thiamine Hcl i have tried but it doesn't penetrate the brain.. No effect.
Now about Allithiamine its that when the disulfide bond is broken to metabolize it, the body uses Glutathione. So glutathione is depleted. Now Glutathione is very essential for the liver for detoxification. Again to replenish the Glutathione, the body uses vitamin B2 riboflavin. The downside with TTFD is it depletes glutathione and Vitamin B2.
So there was a famous biochemist Andy Cutler of the Chelation protocol fame. He said TTFDs are hepatotoxic because of the free sulphur thiol it creates. He was against TTFD use calling it severely hepatotoxic.
On onibasu. com, there are his transcripts where he says TTFD is hepatotoxic.
Does anybody know if TTFD Allithiamine could be used low dose say 25/50 mg in Liver disease?