+* Day 51 of taking TTFD: (B1) :-)

[Gcf51]

*** I ended up with High Blood Pressure taking TTFD. I no longer take TTFD. Based on my experience, I would not recommend TTFD. ***

+* Day 51 (7/7/22) of taking TTFD: In the last 12days: 5days of no TTFD, followed by 4 days of 1/4cap and now on 3rd day of no TTFD. (I stopped taking because my BP was high.) My GP increased my Felodipine from 5 to 10mg on 7/1 (My BP is now lower than when I started TTFD). C/L: 2-1/2tabs twice a day. Mania: under control, Mood: Good, Tremor: tremor starts within 8 sec of holding a cup out, Neck Pain: 3 (1-10 highest being unbearable), Coordination/Balance: still seems good, Sleep: I have been averaging above my normal 7hr.

Today, I got my B1 Blood test from sample taken 6/30: 52** nmo1/L (High, normal range 8–30, I had not taken any TTFD for 4 days and not the morning of, Without a doubt with TTFD excess does not get flushed out). Has anyone had their B1 levels tested?

** I have no idea what lab the VA used. This one has same range testdirectory.questdiagnost...

[Gcf51]

Sulbutiamine, TTFD and other B1’s

Role of the Synthetic B1 Vitamin Sulbutiamine on Health ncbi.nlm.nih.gov/pmc/articl...

I went back and looked at some previous posts on HU and found “Can Too Much B1 HCL (Thiamine HCL) Cause Hypertension or Other Side Effects?” healthunlocked.com/cure-par...

and in a reply JAS9 posted this video.

“Managing Side Effects of Thiamine Supplementation: The Paradoxical Reaction” healthunlocked.com/cure-par...

The video was excellent. I took some of the things mentioned and feel great.

[Smittybear7]

I had mine tested and it came in a normal range that's without supplementing

[Gcf51 in reply to Smittybear7]

High side or low side, Wonder where PD usually falls.

[Smittybear7]

Mine was close to the low side

[Gcf51 in reply to Smittybear7]

Do you take B1, Maybe you should.

What is the research on thiamine and Parkinson's?

A few studies have found an association between low thiamine levels and Parkinson's disease, though studies had limitations. One hypothesis is that thiamine deficiency could increase brain cell stress, damage and loss. Two small, open-label clinical trials of a high-dose injectable thiamine showed improvement on patients' movement and certain non-movement symptoms. But the trials did not include a placebo group, so it is impossible to determine how much of the potential benefit may be from placebo effect. michaeljfox.org/news/thiami....

As it stands I wouldn't recommend TTFD.

[Smittybear7 in reply to Gcf51]

I just tried 500 mg for 3 days and I've had a horrible reaction. So I'm taking a break until they give me an established Carbidopa levodopa and Baclofen. Very frustrating. Just diagnosed with osteoporosa and high cholesterol. So of course I want to put me on drugs for each. Hope what you're doing keeps working for you. Thanks for your help

[TiagoH]

thiamine promotes the movement of potassium to the intracellular space. Maybe that explains the high blood pressure: less extracellular potassium, a higher sodium:potassium ratio

[Gcf51 in reply to TiagoH]

maybe, but everything I just checked says b1deficiency....

[TiagoH in reply to Gcf51]

if I understood correctly, you mention that ttfd raised your blood pressure? So you had ttfd excess and low b1 symptoms?

[Gcf51]

I don't believe I had any low B1 symptoms.