Non-motor symptom medication: Hello all... - Cure Parkinson's

Cure Parkinson's

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Non-motor symptom medication

MissRita
MissRita

Hello all! Curious to know if any of you out there have any experience with or knowledge of any particular non-motor symptom medication?

After recently having a colonoscopy which came back negative and an endoscope that came back negative with a little bit of reflux, my gastroenterologist has surmised as I do that my tremors are non-motor based obviously in my gut but also from my smooth muscle and other parts of my small and large intestine. The reason why my gastroenterologist and I believe that is it seems as though when my gastric system or Vagus nerve or anything connected to the digestive system is reactive, the tremors get worse. Well I am more calm and less reactive in terms of my nervous system the tremors seemingly go away or subside much more. I have an appointment in March with my Neuro office and they are aware of these findings.

Any feedback would be most appreciated!

20 Replies

google "dr matthew phillips nz parkinson's dietary study" he has had good success alleviating non-motor symptoms in parkinson's patients.

MissRita
MissRita in reply to Thal

Thank you!!

Tremor is a motor symptom. Here is a list of motor and nonmotor symptoms:

apdaparkinson.org/what-is-p...

MissRita
MissRita in reply to park_bear

Right I know that the tremor is a motor symptom but my thought is if it’s coming from the Gastro intestinal track which is a non-motor isn’t there a correlation? I think for me it’s really based more around the enteric nervous system all together.

park_bear
park_bear in reply to MissRita

I understand that the G.I. tract events can trigger or aggravate your tremors, but the nerves that control your muscles and that can cause tremor come from the brain.

In any event this involves muscles moving which by definition is a motor symptom.

MissRita
MissRita in reply to park_bear

Ah ok, thx.

Tremor is motor symptom. Non motor symptoms are anxiety, depression, balance, insomnia, urinary urgency ,REM disorder etc..

I fixed all non motor with HDT.

In 2018 I had a colonoscopy and all my symptoms stopped after cleaning my bowel.

MissRita
MissRita in reply to ion_ion

I realize that but gastrointestinal is under non-motor symptom. So I guess my point is when my gastrointestinal tract is symptomatic or having issues than the tremors get far far worse. To me there is a definite connection because when my Gastro intestinal track is not or is digesting food or having gas or whatever, then the tremors are virtually nonexistent. Mind you when I’m hungry I tremor, when I have anything that disrupts the digestive tract I tremor. It’s a conundrum for sure.

ion_ion
ion_ion in reply to MissRita

My tremor stopped when my digestive system was empty. It started to come back gradually after filling up. It looks backwards then yours.

MissRita
MissRita in reply to ion_ion

Yeah that’s pretty funny that you mention that because I go through the actual same thing. When I empty it I get far more tremors and then they subside for quite some time and then I feel better throughout the day and don’t eat nearly as much if at all. I do know that as soon as I do eat the tremors come back. So we’re sort of the same.

Hikoi
Hikoi in reply to MissRita

Sorry miss rita, but are you serious,? You are not trying to see how gullible we are? Having a laugh?

I have never heard of non motor tremor and neither has Dr google.

In PD your gut mobility affects the absorption of levadopa which in turn affects tremor.

You are asking about medication to treat non motor symptoms. Do you mean one medicine to treat them all!

MissRita
MissRita in reply to Hikoi

Lmaoooo I know I have to laugh too but it just seems so odd that a non-motor issue can affect a motor issue doesn’t? I mean I can’t tell you how frustrating this is because I don’t understand it! Lol

MissRita
MissRita in reply to Hikoi

Well it would be nice if I had something to control the non-motor issues that are affecting my gastric issues. Such a conundrum!

did you try cat's claw yet for tremor?

You could also try Avena Sativa (which I take daily, but may take time to benefit you) & Valerian Root (sometimes for sleep). Valerian works extraordinarily well to calm the nervous system, but will also make you sleepy.

Link: motherearthliving.com/healt...

In the past two weeks I have added two new supplements that should complement my Ambroxol use, and hopefully increase its effectiveness:

N-acetyl-L-cysteine

parkinsonsnewstoday.com/201...

pubmed.ncbi.nlm.nih.gov/225...

Ubiquinol (not Ubiquinone otherwise known as CoQ10, but the reduced form Ubiquinol)

pubmed.ncbi.nlm.nih.gov/260...

MissRita
MissRita in reply to DHPSR

Funny that you ask that. I just bought cats claw, the powdered version. I’m not sure how to take it. Sleep for me has never been an issue. I could sleep my life away. But what I’m finding is either I am taking too much L/C or my body might just be resisting it. I have read that many patients don’t always react to L/C very well. For instance I took two tabs of 25/100 this morning and I took it about 2 1/2 to 3 hours ago and I’m starting to sweat already and the tremor hasn’t fully gone away and it seems to be slowly coming back. Mind you I’ve had this tremor since 2015 and was formally diagnosed in 2017 I get anxious about this because I keep thinking maybe it’s progressing faster then I know. I just recently was able to secure an appointment at Strong Memorial in Rochester New York in May so that should be interesting to see what they have to say. I see a doctor where I live now in Syracuse New York and although they are good they don’t seem to be very well versed in the current knowledge of PD and seem to be stuck in the textbook mindset of what PD is and how to treat it. I will see them next Tuesday and that should be an interesting visit.

DHPSR
DHPSR in reply to MissRita

I take a 1/2 tsp cat's claw powder in the am dry on a teaspoon, seems to help some

2 tabs of 25/100 L/C would be a lot for me to take at 1 time, I would probably react too!

MissRita
MissRita in reply to DHPSR

I have tried NAC and although it started to show some improvement, it consistently did not work.

DHPSR
DHPSR in reply to MissRita

It's the combination of Ambroxol with Acetyl L Carnitine and adding NAC, & Ubiquinol that I'm testing now

MissRita
MissRita in reply to DHPSR

I bought the Ambroxol and I am curious as to how it’s working for you?

DHPSR
DHPSR in reply to MissRita

Just over one year now on Ambroxol and it's still working very well to keep me clear of brain fog, reduce the number & severity of my freezing episodes, as well as some small motor improvements (typing, facial gestures for example), & reduced meds (no more ropinirole for me). Starting now to wonder if some larger motor movements aren't benefiting from it now too, like getting out of our deep couch (have noticed has gotten a lot easier for me). So all in all, very happy with how its working for me.

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