Amy Lindberg brought this to my attention describing it as the mother load on FUS. Indeed. List all the trials and treatment sites.

[MBAnderson]

fusfoundation.org/diseases-...

[jimcaster]

This is great! I am still baffled as to why Pallidothalamic Tractotomy (PTT) is not more widely studied and/or available. It seems to be able to treat a much broader array of symptoms, while the other forms of Focused Ultrasound seem geared toward addressing only one symptom (tremor or dyskinesia), depending upon which type is used.

[Drummer67 in reply to jimcaster]

1000% agreed Jim! the more i read the more I can not understand Why FUS PTT is not being studied in the US as it appears so promising.Why does FUSfoundation.org not "carry the ball" On this???????

[MBAnderson in reply to Drummer67]

I believe that's the purpose of the foundation -- to spread the word.

[lenamm in reply to jimcaster]

It's a safer and better procedure because you only need a 4-5 mm lesion to completely destroy the PTT but when I was there for my last surgery I learned if it is done poorly it is way more dangerous as an important cognitive center is right next door. Sonimodul does two a week but if you start trying to do many a day with inexperienced surgeons you could be in for disaster . Maybe why more surgeons don't want to take it on.

[Despe]

"Focused ultrasound is an early-stage,. . ."

Also, Summary of Workshop "Patient Selectionl Patients with early/mild disease (around 3 years post-diagnosis) without neurodegeneration.

So hurry!! Not good.

[Trixiedee in reply to Despe]

I’ve had Parkinson’s for 20 years and it worked wonderfully for me.

[Despe in reply to Trixiedee]

I know as you have said before that you have had PD for 20 years. Why do they include duration of PD as a criterion?

[lenamm in reply to Despe]

For PTT they do not beyond that you have to have non medication responsive disease for at least a year.

[reedboat2 in reply to lenamm]

What’s the logic behind the medication resistance criterion? Thanks- JG

[lenamm in reply to reedboat2]

The PTT has no normal function when meds don't work anymore is safe to destroy.

[Trixiedee in reply to Despe]

Plenty of people have had FUS who have had Parkinson’s for under 5 years. As Lena says, it’s based on whether the meds work or not.

[chartist]

Thank you for the link, Marc!

Art

[jeeves19]

Can you have FUS if you have had DBS?

[MBAnderson in reply to jeeves19]

Yes, but only if all the hardware has been removed.

[lenamm in reply to MBAnderson]

Which is usually not possible without causing brain damage unless done soon after implantation .

[Trixiedee in reply to jeeves19]

It’s really rare to have DBS hardware removed and the rare occasions I have heard about have caused a stroke.

[jeeves19 in reply to Trixiedee]

😕

[Kia17]

Hi Trixiedee

For how long will the efficacy of FUS last? Is the procedure reversible? Does FUS affect on brain’s executive functions?

Any improvements on non motor symptoms?

[Trixiedee in reply to Kia17]

Nobody knows how long it will last as it hasn’t been practiced for more than about 7 years. However I have a friend who had a thalmalotomy surgically about 30 years ago and the effects are still there. So I believe it’s permanent. It doesn’t improve or worsen executive functioning as far as I know. Not in my case anyway.

[Trixiedee in reply to Kia17]

The main non motor symptom that improved with me was anxiety and vertigo that was caused by Sinemet. I’m still taking Sinemet but with no side effects.

[Kia17 in reply to Trixiedee]

Thank you very much Trixiedee. Wishing you all the best.

[Trixiedee in reply to Kia17]

Also it isn’t reversible but the results for myself and everyone I know are so good that they wouldn’t want it reversed.

[Kia17 in reply to Trixiedee]

Amazing. Thank you