Anyone try large dose of Sinement

[nlaung]

Anyone taking Sinemet more than 200mg(example 300mg) in a single dose?

Thank you.

[koshca]

Yes, easy.

[nlaung in reply to koshca]

Thank you.

I only have 2hr on time for 1 tab of 200mg (C\L). I am going to try 1 and 1/2 tab.

[Nivrac77--]

My neurologist just upped my sinemet from 100mg to 250mg. So far (after 3 months), no side effects and it keeps working better and longer than 100 mg. I am satisfied with the new dose. Blessings to you - hope it works for you.

[nlaung in reply to Nivrac77--]

Thank you for your reply.

[condor39]

I have slowly worked up to Madopar (Actually, Prolopa, the Canadian version) 25/100 and I take three, every three hours, 6,9,12,3,6,9, he two on going to bed, and two in the night when I wake. So that is 2,200 mg a day. I weigh 230 lbs which is relevant. No side effects.

[nlaung in reply to condor39]

Thank you for sharing about your dosing.

I will try taking that way.

[laglag]

Talk to your neurologist first. I took too much for a couple of months & it gave me a lot of dyskensia & shaking all over for several months & I almost didn't make it.

[nlaung in reply to laglag]

Thank you.

I will talk to Nero.

[Sapeye2020]

have been on Sinamet and a Canadian Generic of same strength for

~ 3 years, I dose 5 times in 24 hrs *am, 12:30 pm, 5 pm, and 9:30 pm and when (IF) I wake from my sleep. I take each dose with water except the 8 am it is coffee. 2 pills = 75/300 from 1-25/100 and 1-50/200. the 2 brands are similar but not exact version, the generic is less 'even dispersal' of active component, IMHO......

'HTH