I was diagnosed in January, 2014 and now take Sinemet 3x a day. My neuro added Selegiline 5 mg twice a day. I have been on this schedule for 5 weeks but have not seen any changes to my condition. Has anyone else experienced this. I would be most grateful to hear your thoughts on this medicine one way or the other. I think I will give it one more month and then decide what to do. Thank you very much.
Barbara
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barbarapal
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well barb i would not take sinemet if i got them for free. i threw them away i was taking madopar 200/50 3 times a day, i thought ill try the sinemet i ended up in hospital for 4 days,i also take azilect 1 per day 1 mg i will stick to that now.talk to your doctor about it.hope this helps.
I read Azelect is better than is better than Selegiline in slowing the progression of the disease, plus you don't have to avoid wine while you are on it.. I switched last year
Barbara, this disease is so variable, often times what works for me, doesn't come close to helping you. It could take a year, maybe longer, to find the right recipe for you. That said, I have been on Selegiline for over 3 years. I'm 66, and was diagnosed Aug 30, 2010. Selegiline is a MaOB inhibitor. MaOB loves to gobble up levodopa. Selegiline helps to put the brakes (hence inhibits) on MaOB. This allows more levodopa availability in the brain.
While having other problems, I was taken off Selegiline. Within 2 days I realized the need to get back on it. Funny that such a small pill could have such a major impact!
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