Hello Everyone
My grandson has just had his MMR vaccination, which consist of three live vaccines. Do I need to stay clear of him while the viral components replicate within his little body as he will be shedding live virus. Very difficult to find a specific answer on the drug company's info sheet.
Best wishes
MaudMarie
Hi MaudMarie,
I agree it is very hard to gain a specific answer from the information sheet, information also seems conflicting and although possible is not documented.. Of course we are aware CLL patients are contraindicated from receiving live vaccination. Complications to the immune compromised from vaccine that contains activated particles of viruses or bacteria are well documented. From what i understand this is worse following treatment although CLL patients may be immune compromised to different degrees at all stages of their individual journey not just following treatment.The immunodeficiency of chronic
lymphocytic leukaemia bmb.oxfordjournals.org/cont...
Chicken pox vaccine shedding has been discussed within the community. But I cannot locate a discussion about LIVE MMR vaccine shedding by vacinees and risk to CLL patients in the vicinity. It appears there may be some risk during weeks 2,3 and 4 following vaccination. Your suggestion may be wise for a month. I look forward to the experienced input from the group. I suggest you consult your consultant.
The most recent item within precautions I could find made me curious. It came from a GSK document July 12, 2011 The PRODUCT MONOGRAPH for PRIORIX-TETRA
It suggests transmission of varicella vaccine virus may occur very rarely between healthy individuals and cause a physical reaction. But I cannot find any references to transmission effects to the immune compromised!
gsk.ca/english/docs-pdf/pro...
FROM PRECAUTIONS
"Transmission of measles, mumps and rubella viruses from vaccinees to susceptible contacts has never been documented, although pharyngeal excretion of the rubella virus is known to occur about 7 to 28 days after vaccination with peak excretion around the 11th day. Post-marketing experience suggests that transmission of varicella vaccine virus may occur very rarely between healthy vaccinees who develop a varicella-like rash and susceptible contacts."
Interesting from the Public Health Agency of Canada
phac-aspc.gc.ca/publicat/cc...
FROM PRECAUTIONS
“Transmission of measles, mumps and rubella vaccine viruses from vaccinees to susceptible contacts has not previously been documented even though pharyngeal excretion of the rubella virus may occur from seven to 28 days after vaccination. Transmission of varicella vaccine virus occurs rarely between vaccinees who develop a varicella-like rash and susceptible close contacts.(3)”
Literature from MERCK &CO, INC Issued December 2010 Printed in USA
merck.com/product/usa/pi_ci...
M-M-R® II (MEASLES, MUMPS, and RUBELLA VIRUS VACCINE LIVE)
FROM PRECAUTIONS
“Excretion of small amounts of the live attenuated rubella virus from the nose or throat has occurred in the majority of susceptible individuals 7 to 28 days after vaccination. There is no confirmed evidence to indicate that such virus is transmitted to susceptible persons who are in contact with the vaccinated individuals. Consequently, transmission through close personal contact, while accepted as a theoretical possibility, is not regarded as a significant risk.33"
Thank you Hairbear. I'm taking the cautious route - and it's miserable. One of the biggest long term problems with having CLL is that it disrupts the relationship with you grandchildren who bring such life, joy and innocence to our complicated lives. And it's hard for them too if they're used to having fun with you. I'm sure that everyone affected with CLL feels the same.
Hi as you say grandchildren bring such joy into your life. I have had treatment and one of the reasons I want to keep going is to see my grandchildren grow up. I find it hard when I would like to do more active things with them, as I feel I would if I didn't have CLL, but know I have to pace myself. Best wishes.
Yes miserable, one of the hardest complications of CLL life I think. How many kisses and moments do we miss ?
And yet we answer the door to the delivery man who obviously has at least a bad cold, people cough and splutter all around us in supermarkets and the mall, and who knows what illnesses they wheel around in prams.
I have seen doctors post two and four weeks as times when we might be vulnerable. I don't think anyone really knows the answer. When I was teaching this was a concern, as many of our students were immigrants, which meant that they would be getting these vaccines at a later time than normal, but legally I couldn't ask or be told if one of my students had received them. I am old enough to have had all of the "childhood diseases" before the age of vaccines (I'm really old!), but this was something that was always on my mind when I received a student new to the country. I never had any problems, but in a situation in which I had a choice, I think I would err on the side of caution, hard as it might be. I know for some this simply isn't an option - parents of small children, for example, but have seen families do very inventive things to minimize exposure.
Can I be in the same house as a one year old child who had MMR vaccine about a week ago but not pick her up or hug and kiss her or do I have to avoid even being in the same house together??
We are invited to dinner and she and her parents will be there too
Thanks for taking the time to respond ....
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