A friend recommended dragon fruit to help with the slight anemia caused by the Imbruvica. I don’t remember this being on the of no no fruits such as grapefruit or Seville oranges, but I wanted to check with the members of this forum.
Aside from the unproven claims of benefit to the blood, I enjoy the fruit and would not mind including it in my diet.
A number of tropical fruits were tested for CYP3A inhibition. Dragon Fruit was included but the only one reported to have an effect in the abstract was Star fruit.
researchgate.net/publicatio...
Dragon Fruit has the least activity.
Star Fruit is the worst of all those tested. Pomegranate and common Pawpaw also have greater CYP3A inhibition than White Grapefruit. Pomegranate by quite a large margin.
Black mulberry may be in the frame as well.
pubmed.ncbi.nlm.nih.gov/164...
But in vitro testing fails to take account of bioavailability, if the active component fails to pass though the gut wall it's actual inhibition of CYP3A will be much reduced.
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