Hi I am about to complete the Flair Trial, having completed 6 years on the ibrutinib and rituximab arm in March 2024.
I have decided to follow through with the Static trial where patients will be either off or on ibrutinib.
The purpose of this trail is to see if giving patients a drug holiday prevents or reduces resistance to ibrutinib. If treatment is needed they return to ibrutinib.
Patients on ibrutinib can choose to remain on it and still be part of the trial, or let the computer decide for them through randomisation.
Initially I thought I would choose to stay on the drug as it is working well for me right now. Now I am pondering with randomisation as it may work well for longer if I am allocated a break Do I stay with the devil I know or take a risk?
I feel blessed to have been on the Flair trial and doubly blessed to be offered Static.
I wonder if anyone else is or has been in the same position as me?
If so I wonder if you are willing to share your experiences or views on the subject?
Ann