Covid Pfizer vaccine acalabrutinib efficacy one case

[Mik_]

One case description:

1. dose one: none antibodies was developed, antibodies test was done 21 days after vaccination. Patient under acalabrutinib over 12 months

2. Dose two: done in 30 days dose one, last acalabrutinib taken 36 hours before second vaccination and patient back to acalabrutinib in 5 days after second vaccinationant. Antibodies test is done 21 days after vaccination. POSiTiVE.

[Direstraits12]

That’s great news! I’m also on acalabrutnib and have had both Pfizer jabs. Very little solid research on the efficacy of the vaccine for cll patients. There is a large study being done by the university of Birmingham which I’ve volunteered for. But the results won’t come out for a while yet.Again great news.

[bulldozer4264]

And also the study being done by the LLS. My wife was in the same situation as Mik, with the same results. Still trying to figure out what level of immunity was measured and reported in the LLS blood analysis result.

[Mik_ in reply to bulldozer4264]

Actually, it could be an estimation based on number of antibodies. However, to the best of my knowledge such test has been set in US ( at least in my University). The main issue, however, is BKT (acalabritinib).

[BallyB]

Thanks for the update, I am on acalabrutinib and I am assuming it is effective.

[Mik_]

Sorry, there is typo error: the test has not been set up. Regarding acalabrutinib you may need for sure both doses and if your oncologist allows you to stop acalabrutinib for a week it may increase a chance to develop antibodies, but it has to be your oncologist decision.