Negative spike test: Just tested negative for... - CLL Support

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Negative spike test

Barclays profile image
19 Replies

Just tested negative for spike test for Covid with low blood CLL readings after 1st Oxford jab hope second one produces some immunity

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Barclays profile image
Barclays
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19 Replies
Pacificview profile image
Pacificview

When did you get your first shot?

Barclays profile image
Barclays in reply to Pacificview

Six weeks ago

Pacificview profile image
Pacificview in reply to Barclays

A phase two study on 560 participants in India ( half were over 70) found this. After 1st shot it provoked a tcell response within 14days. An antibody response within 28 days of booster shot. Article made no mention of any participants being CLL patients.

Barclays profile image
Barclays in reply to Pacificview

Let’s hope that’s right

Pacificview profile image
Pacificview in reply to Barclays

I seem to recall another article that we talked about here within recent days.Its the second shot thats important for the immune compromised get at proper timing.

Pacificview profile image
Pacificview in reply to Barclays

You are early watch and wait. With a slightly immune compromised system. You will probobly end up with some good protection after the second shot as described in the article. You still have a lot of healthy Bcells and we dont have a tcell disease. My understanding is that the tcell response to these vaccines are the most durable.Personally, I doubt very much that a treatment naive watch and wait patient with almost normal numbers. After having been fully vacinated will be taken out by covid.

Barclays profile image
Barclays in reply to Pacificview

Many thanks you’ve certainly put my mind at rest

Susanbarratt profile image
Susanbarratt in reply to Pacificview

Thankyou I only joined today and you've been encouraging. My husband was diagnosed 18 months ago after a routine cholesterol test and is on watch and wait. The results published so far for the vaccination are disappointing. The lifting of lockdown is worrying.

Alobs profile image
Alobs

Sorry to hear that. But you may still have developed some immune response, e.g. your memory T cells

Barclays profile image
Barclays in reply to Alobs

Hope so but don’t really understand it all

Alobs profile image
Alobs in reply to Barclays

Nor do I...but I think the T cells may have memorised the immune response after the jab, so the immune system can respond to any C19 infection by producing the neutralising antibody B cells.

Trish67 profile image
Trish67

Hi Barclays, I did the same! My consultant said that they are finding CLL patients need their second jab to see any real immunity. Roll on that second jab !

Barclays profile image
Barclays in reply to Trish67

Thanks my second jab is due end of April

Pacificview profile image
Pacificview in reply to Barclays

Get all the vaccinations you can while you still have a fairly healthy immune system.

stevesmith1964 profile image
stevesmith1964

Hi, I had the vaccine 8 weeks ago, Covid19 6 weeks ago.... test my Spike protein Neutralising antibodies weekly..... still non detected. I am resigned to not having any and thus not travelling abroad once immunity passports are introduced for travel.

Poodle2 profile image
Poodle2 in reply to stevesmith1964

This is very disappointing to hear...I had covid 2.5 months ago and it was truly awful and I had the jab a week ago. To think that I might get it again...it's depressing really. I hope it's not just the B cells that play the important role in generating immunity.

SeymourB profile image
SeymourB

Barclays -

Which spike test did you get? Was it the Qualitative test, the Semi-Quantitative, or the Quantitative, or something else?

=seymour=

Barclays profile image
Barclays in reply to SeymourB

Not sure it was the kit from test for all after a vaccine jab test

SeymourB profile image
SeymourB in reply to Barclays

Was it this one?

gov.uk/register-coronavirus...

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