MRD negative

[Racing1961]

After 2 years on Venetoclax, I am now MRD negative. Such fantastic news. The Royal Marsden in London have been absolutely brilliant and can’t thank them enough 😊

[Ghounds]

Wonderful news, wishing you a long and healthy remission.

[Poodle2]

Wonderful news!🎉

[annmcgowan]

Congratulations long may it last.

Ann

[Skyshark]

Not just uMRD but uMRD5! Really very good.

[Steffi50]

Hi Racing 1961 really good to hear this. In fact more than good - wonderful! Just quick question re treatment as I am also at the Marsden, why 2 years on V? I am on 12 mths (6 mths in) V&O. I did not know that you could just take a single drug such as V. What dosage did you take for the 2 years.

[Racing1961 in reply to Steffi50]

Hi Steffi50, is this your first treatment? I had a very bad experience with FCR that nearly killed me back in 2018. I only had one round and it was stopped. I started V+O in 2021 but only had 1 O infusion as I didn’t do well with it. I think that’s why I was kept on V for longer. I took 400mg for all 2 years.

[Steffi50 in reply to Racing1961]

Oh that explains it. Yes, first treatment. Luckily I hung on W&W long enough to avoid FCR. I always said I would never want to take it. I think O is very harsh. I have one to go(but all treatment stopped last week as my neutrophils have tanked or as the Marsden puts it LL) but hopefully will get going again next week. Fab about you though. Gives me hope

[Shefflass in reply to Steffi50]

I am also on 2 years Venetoclax but on the V+Rituxinab protocol. I understand V+O is given as first line treatment but V+R is given if you've had other treatments in the past.

Congratulations Racing1961. What wonderful news!

[Milla15]

Yay! 🎉🎈🎇🥇

[jillybird13]

fantastic news, so pleased for you . It’s a great feeling isn’t it . I got my MRD last week 👍

[spi3]

Totally awesome news and blessed! Congratulations

[LeoPa]

Congrats, must be music to your ears! No evidence of CLL cells 😁🤞

[MistyMountainHop]

Bless you😃

[CycleWonder]

This is the best of the best of the best news you can get! Congratulations!🎉🎉🎉🎉

[skipro]

congratulations!!!!

Were you on Ven alone, or in combination with Obin or Ritux or other?

Also, Were you relapsed beforehand? I hear the protocol is 1 year for Tx naive and 2 years for relapseds/

I am so happy for you and hope this is a lasting response!!!!

[Racing1961 in reply to skipro]

If you look back at my previous posts you will see what an awful time I had with FCR. Managed to avoid more treatment for 2 years. Was supposed to have V+O but reacted badly to the O so ended up having 2 years of just the V at 400mg a day.

[vman82]

AMAZING NEWS !!! wishing you an infinite remission !

[garyherm]

great news

[DinosaurDad]

Congratulations! Welcome to the "I was treated with V and am now MRD negative" club!

[cyclist123]

Congrats to you. Thx for sharing.

[Chi-town_Girl]

Fantastic news!!!! Celebration time for you!

[Fran57]

Amazing! 🎉 🥳

Fran 😉

[PulsedTherapy]

Venetoclax is really an amazing drug. Congratulations. What was your TP53 status?

[Racing1961 in reply to PulsedTherapy]

There is no evidence of TP53 mutation or deletion 😊

[Skyshark in reply to Racing1961]

Was VenR on a trial or did you have to ask for the MRD test or was it Royal Marsden SOP?

[Racing1961 in reply to Skyshark]

No, it wasn’t on a trial and I didn’t have to ask for the test. I was treated at The Royal Marsden.

[Pearlpink]

fantastic news!!🎉🎉🎉🎉