Vaccine on or off treatment

[Davidcara]

Will ask MD but wondering... If off ibrutinib for a week do to a procedure... how could this affect vaccine response if it happens shortly before, shortly after, or in between 1st and 2nd vaccine.

[cllady01 Former Volunteer]

That is a question I had not thought about. Please let us know what your DR. says. It will most likely be a situation not been dealt with yet, but your Dr. will have some idea of how to handle that or other situations that will not be the normal situations.

[bkoffman CLL CURE Hero]

Might improve response based on the hep B vaccine data and BTKi suggesting they impair response, but that is a big logical jump.

[Mik_ in reply to bkoffman]

Interesting, I learned that BTK blocker increase replication for Hep B and some treatment like vemledy is strictly necessary. Is it true?

[Davidcara]

Spoke to my oncologist, did not have much to say one way or the other. Although, I’m not a big fan of these phone appointments. Prefer office visits for better dialogue communication