Dramatic weight loss on imbruvica: I am... - CLL Support

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Dramatic weight loss on imbruvica

Cali69 profile image
10 Replies

I am finishing up week 4 on imbruvica. Since starting I have dropped 20 pounds. Is this normal? No other side effects.

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Cali69 profile image
Cali69
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10 Replies
Zia2 profile image
Zia2

Hi I posted something similar earlier today. Can you read it?

Lisa-1959 profile image
Lisa-1959 in reply to Zia2

Agree...I just replied on your post. Had the same issue with weight loss.

Rose-white profile image
Rose-white

I struggled to keep weight on when I started but more because I had upset tummy For the first 6 months. I’ve stopped losing now and am stable.

Some people report weight gain but I haven’t experienced that.

CBeauty profile image
CBeauty

I am on Acalabrutinib (7 weeks) and have noticed weight loss. Holding steady now. I started to lose weight from CLL before treatment and thought when I started treatment the weight would come back. Nope, just holds steady even though I eat more now. However I give some credit to positive lifestyle changes.

BluMts profile image
BluMts

20 pounds is a huge amount to drop in a month. I lost weight when I began IB but not 20 lbs and I had nausea, lost appetite and there is one other thing. I feel tired with normal activities and thought I should not as my blood results were good quickly and lymph nodes became normal quickly. But on shielding I've put on weight. Do think IB takes a lot out of me... But 20 lbs loose is dramatic and worth investigating.

Smith123456 profile image
Smith123456

how are your blood counts

Cali69 profile image
Cali69 in reply to Smith123456

WBC is still high and climbing, RBC went down a smidge, and platelets are starting to come up.

LeoPa profile image
LeoPa

Cali, half of the weight lost is probably water. 20 pounds of fat is what a regular person burns in a month in terms of calories. So it can't be all fat and muscle, can it? You'd have to fast for a month to loose that much. Did you start eating less carbs lately? That could have a side effect of a large water loss, which is nothing to worry about. If there are other problems with water retention then I don't know. Worth investigating.

Cali69 profile image
Cali69 in reply to LeoPa

Really haven’t changed eating habits.

lindalou5 profile image
lindalou5

I lost 80 pounds in four months when I first started IB. I did lose fat and muscle, and friends /family thought I was dying. I have since gained about 25 back. I feel like I was half out of it when this was happening and was a bit concerned, but the doc did not seem that concerned. I did have excess weight to lose.

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