Hi all, new to posting, so hope to be concise as possible. Currently on ibrutinib now for 14 months with a wonderful response other than the multitude of irritating side effects. My question is do I continue to be satisfied with where I am in treatment or should I be more aggressive in seeking a complete cure while it is beaten back? I always wonder am I doing enough. I was diagnosed in 2012 with CLL at age 41. Due to rapid doubling time and symptoms it was decided I needed treatment. Took 6 months of FCR ending in July 2013 with a CR. I relapsed with a very aggressive vengeance in December 2014. This time it returned with 17p deletion, ZAP-70 & CD38 positive with complex karyotype, about every bad prognosticator you can get. Should I be seeking out more aggressive therapy, what happens/options if ibrutinib stops working? I'm "only" 45 with two young children and I want to be around to see graduation, weddings and grandchildren!
Any info is greatly appreciated.