Ibrutinib

[Zappymom12]

My husband’s side effects are worse late afternoon early evening. I stay awake until I am sure he is more settled. He has horrible chills. He’s beginning to have head aches as well. He had headaches with FCR. Any advice on how to best comfort him or make life easier during Ibrutinib?

[cllady01 Former Volunteer]

Zappymom, were I you, I would contact the CLL Dr. treating your husband. Chills can mean fever, and fever can mean infection.

Infection can spread fast and become very serious. Sorry, don't mean to scare you, but do want you to know the seriousness of what chills can mean.

[Zappymom12 in reply to cllady01]

We spent all day Friday in the ER and talked to his oncologist twice that day. His lymph nodes are larger after a call from him on Saturday. I do appreciate that input. I had no idea infection could spread quickly. I will continue monitoring him closely.

[cllady01 Former Volunteer]

IMBRUVICA® (ibrutinib) Side Effects | CLL

imbruvica.com/cll/side-effects

IMBRUVICA® (ibrutinib) Side Effects for Chronic Lymphocytic Leukemia ... so important to tell your healthcare team about side effects at any point in your treatment.1 ... Infection is a serious possible side effect of IMBRUVICA®. Notify a healthcare professional immediately if signs of infection (eg, fever, chills, weakness, and ...

EDIT ADDED: If you are still concerned, call the CLL Dr. anytime--if your husband relapsed from one med, he may have an allergy to this one-

[Zappymom12 in reply to cllady01]

He had anaphylactic shock from Nuelasta while on FCR. He only has chills in the late afternoon and evening. I will make the call.

[Cllcanada Top Poster CURE Hero]

Difficult time.. for certain... call the CLL doctor...

Welcome to the group.. please let us know how things are going... 👍🏼

~chris

[Zappymom12 in reply to Cllcanada]

Tonight...first night without chills. Fatigued but so much better. Good news.

[MsLockYourPosts Passed Volunteer]

Different treatment, but I had terrible chills when I was first treated. My doctor did labs stat in the morning and everything tested as in range. No fever. By evening I was in the ER, septic. Still no fever. Please get this checked!

[Zappymom12 in reply to MsLockYourPosts]

He’s not having chills tonight. I’m so glad. I will stay with my decision to have him seen. He was in the ER all day Friday and we saw the Oncologist twice that day because of the chills and low grade fever 100.8 F. The Oncologist called Saturday (the following day) to check on him. Today is the first day without chills.

[kathymac52]

Prayers sent your way....let us know how he is.....

[Zappymom12 in reply to kathymac52]

He made it through the night without drenching night sweats and chills. He was clammy to touch. Fatigued today, lymph nodes aching, and slight headache. Thank you! Praying that I am secure, loving, kind, and courageous for him.

[kathymac52 in reply to Zappymom12]

I have no doubt you will be....remember to take care of yourself as well........

[Zappymom12]

He is having a lot of fatigue. Usually two naps a day.

[Zappymom12]

Today he slept almost the entire day. Please anyone. Did you have this type of fatigue?

[Zappymom12]

It’s been six months since starting Imbrutinib. Finally out of the critical phase! Thank you God!